Báo cáo y học: "Nitric oxide, leukocytes and microvascular permeability: causality or bystanders" pdf

... whereas wild-type controls and mice lacking endothelial NO synthase (eNOS –/– ) presented with similar less pronounced Commentary Nitric oxide, leukocytes and microvascular permeability: causality or bystanders? Balázs ... sepsis-related microcirculatory failure, and in this context leukocytes are thought to assume major importance. However, the role of nitric oxide (NO) i...

Ngày tải lên: 13/08/2014, 08:21

... increased activity of NOS may represent predominantly of nNOS isoform. In reper- fusion group the activity may be attributed to iNOS and nNOS and increased activity may be mainly by iNOS due to ... conditions and were given normal diet for 5 days and decapitated and the different brain regions (CC, CB and BS) were used for study. It was reported by Ananth et al (23) that 5 da...

Ngày tải lên: 26/10/2012, 09:07

... pulmonary artery showing no immunocytochemical positivity for nNOS. (F) Control patient small pulmonary artery showing no positivity by immunocytochemistry for nNOS. × 400. Respiratory Research ... Pathology, Glasgow Royal Infirmary, Glasgow, UK and 4 Department of Physiology and Pharmacology, University of Strathclyde, Glasgow, UK Email: Thomas Hoehn* - thomas.hoehn@uni-duesseldorf.de...

Ngày tải lên: 12/08/2014, 14:20

... mM of NOR-1 for 30 min, 1, 3, 5 and 24 h or PKC inhibitors for 30 min. MUC5AC promoter activity was determined by measuring luciferase activity after the lysing the transfected cells and normalizing ... markedly increased the MUC5AC promoter activity and mRNA expression, mucin synthesis and ERK1/2 phosphorylation. The PKC inhibitors also inhibited the NOR-1 induced MUC5AC mRNA and...

Ngày tải lên: 12/08/2014, 15:20

... additional inflammatory cytokines such as IL-1β and TNF-α are derived primarily from macrophages (not Th1 or Th2-derived) and also play Respiratory Research 2009, 10:3 http://respiratory-research.com/content/10/1/3 Page ... inflammation describes an imbalance in the Th1 and Th2 lymphocyte and cytokine profile. The former produce primarily IL-2 and IFN-γ, and are generally respon...

Ngày tải lên: 12/08/2014, 14:20

... pro-inflammatory actions by other mechanisms. For instance, NO • can promote the expression of pro-inflammatory cytokines or cyclo-oxyge- nase (responsible for the formation of inflammatory prostanoids) ... mediated by various actions, either by NO • itself or by secondary RNS, and the overall biochemistry of NO • is deceptively complex. Moreover, the metabolism and chemistry of NO •...

Ngày tải lên: 12/08/2014, 18:20

... medication (typical vs atypical antipsychotic drugs). For the total schizophrenic sample, PAS and SAS total scores were significantly and positively correlated with negative symptoms (SANS total score ... the 'core' def- icits of schizophrenia. Today, it is still commonly included by many authors [8-15] in the negative symp- tomatology of schizophrenic disorders. For example, An...

Ngày tải lên: 08/08/2014, 23:21

... admission and discharge may vary by country. Controlling for symptoms and function scores, this analysis indicated that patients in the US are more likely to be admitted faster and also more likely to ... Symptomatology <75 Medium Symptomatology > 75 and <95 Highest Symptomatology > 95 Reference groups were lowest symptomatology for PANSS scores, high functioning for PSP s...

Ngày tải lên: 08/08/2014, 23:21

... 1 Glycolytic chain intermediary metabolism, glycerol and glycerophospholipid formation and the citric acid cycle. Simplified diagram of the intermediary metabolism of the glycolytic chain and ... to hypoglycemia, reproduction, modulation of tau phosphorylation, metabolism of amyloid precursor protein and β-amyloid clearance, neuronal survival, and memory [9]. Since the observation b...

Ngày tải lên: 13/08/2014, 10:20

... lung injury (ventilator-induced lung injury (VILI)) characterized by an inflammatory response morphologically and histologically indistinguishable from that caused by bacterial lipopolysac- charide ... Jackson Laboratories (Bar Harbor, ME, USA) and the National Laboratory Animal Center (Taipei, Taiwan). Heterozygotes (+/-) are used because homozygotes exhibit lower fertility and female...

Ngày tải lên: 13/08/2014, 08:20