Báo cáo y học: "Recently published papers: More about EGDT, experimental therapies and some inconvenient truths" potx

... of breathing a hydrogen oxygen atmosphere and half to nitrogen oxygen. The anti-inflammatory effects of the hydrogen were very striking. The impracticality of repeating this study in any clinical ... in mortality at 7, 14, 28 and 90 days, or indeed, serial sequential organ failure assessment (SOFA) score or a variety of haemo- dynamic end points. The study was prompted by limited evidence...

Ngày tải lên: 13/08/2014, 08:20

... mortality and transfusion. Vincent and colleagues used a propensity scoring system to identify two distinct groups and control for confounders, and found an odds ratio of 1.37 for mortality in transfusion ... surgery, trauma and sepsis patients. Their findings confirmed further that when therapy is aimed at improving oxygen delivery (especially in the severely ill, in whom control g...

Ngày tải lên: 12/08/2014, 19:21

... phenomenon. Obesity Against the background of the global epidemic of obesity, the impact of body mass index on the short-term outcomes of critical illness has been investigated by Tremblay and Bandi [5]. ... illness polyneuropathy Valuable long-term follow-up data from survivors of critical illness who had spent more than 28 days in intensive care were presented by Fletcher and colleagu...

Ngày tải lên: 12/08/2014, 19:22

... almost entirely based on the DECREASE series [10] by Poldermans and colleagues, which were “mainly observational, done primarily only on vascular surgery patients and in only one country in the world”. ... 7 days and 3.1% at 28 days after admission. Adjuvant corticosteroid therapy was not associated with reduced mortality in any age group. The hazard ratio (HR) for children younger than...

Ngày tải lên: 13/08/2014, 11:22

... diaphragmatic injury caused by mandatory ventilatory modes coupled with the sedation and sometimes neuromuscular blockade required to achieve them may well have been underestimated, to say nothing of ... patient, however, BNP is merely a marker of cardiac strain and is universally elevated in hyperdynamic and shocked patients, regardless of the aetiology. In this study, 41 patients who...

Ngày tải lên: 13/08/2014, 11:22

... a more recent paper on the effects of methylprednisolone in unresolving acute respiratory distress syndrome [10], and may account for a therapeutic modality by which high-dose steroid therapy ... Jr, Landry DW, Townsend RN: Low-dose vasopressin in the treatment of vasodilatory septic shock. J Trauma 1999, 47:699-703. 6. Tsuneyoshi I, Yamada H, Kakihana Y, Nakamura M, Nakano Y, Boyle WA...

Ngày tải lên: 12/08/2014, 18:21

... recovery of gastrointestinal motility may be effective salt and water balance. In a study by Lobo and colleagues [4], prompted by Commentary Recently published papers: We are what we eat? LG Forni Consultant, ... recent study reported by Yap and coworkers [7]. They retrospectively studied more than 1000 patients over an 18-month period, their hypothesis being that serum hypoalbumi...

Ngày tải lên: 12/08/2014, 18:21

... reported by Weber and colleagues [22]. Sadly, adoption of this technique, in the UK at least, awaits the deliberation of the government and judiciary. Finally, if you have been seduced by the attractive ... 2002, 166:1-2. 3. Brealey D, Brand M, Hargreaves I, Heales S, Land J, Smolenski R, Davies NA, Cooper CE, Singer M: Association between mito- chondrial dysfunction and severity and...

Ngày tải lên: 12/08/2014, 19:21

... particularly by doctors. Which agent(s) should be used, and how much and how often? These are important questions but they are not easily answered. Anxiolysis, analgesia, amnesia and sedation ... measures were employed, including costing, quality of sedation, haemodynamic stability and time to extubation, among others. Unsurprisingly, the studies showed wide clinical heterogeneity an...

Ngày tải lên: 12/08/2014, 19:22

... cancer. Perhaps the study that will attract most attention is that by Sandham and coworkers [4]. This is an impressive randomized trial that compared goal-directed therapy guided by pulmonary artery catheter ... of severe injury. What the study does highlight is the fact that our knowledge of critical illness polyneuropathy and myopathy is scant. The challenge now is to try to identify ri...

Ngày tải lên: 12/08/2014, 19:22