Báo cáo y học: "Improvements in the outcome of children with meningococcal disease" pptx

... addressed. Changes in PICU practice may lead to an increase in these ‘hidden’ MCD deaths. In a highly centralised PICU system Commentary Improvements in the outcome of children with meningococcal disease Fauzia ... position of having collected their data prospectively. The authors found that survival of children presenting to their unit with MCD correlated with...

Ngày tải lên: 13/08/2014, 08:20

... baseline (before the start of the inter- vention) and at final follow up ( directly after the end of the intervention period). The intervention period consisted of one or more appointments with the ... pain (including RA-rela ted pain) a reduction of one point in NRS pain represented a MIC [36]. The NRS change score in our study may therefore be interpreted as a cl...

Ngày tải lên: 10/08/2014, 21:24

... procollagen prolyl hydroxylases (P4HA1 and P4HA2), lysyl oxidase (LOX) and lysyl hydroxylases (procollagen lysyl hydroxylase and procollagen lysyl hydroxylase 2). Similar links between hypoxia and ... However, the role played by other members of the HIF family in the pathogenesis of SSc has not yet been investigated in detail. Insufficient response to hypoxia: dysregulation of...

Ngày tải lên: 09/08/2014, 01:22

... Further evaluation of the effect of genetic variation in MMP3 on the level of joint damage in RA is therefore required. The increasing comprehension of the role of genetics in disease outcome in ... Additionally, erosions often initially present in the small joints of the feet, and appear in the small joints of the hands at a later point in the...

Ngày tải lên: 09/08/2014, 10:23

... contributors to the pathogenesis of RA. MCs may be considered the immunological sentinel of the syn- ovium, acting immediately in the event of joint trauma by liber- ating an array of proinflammatory mediators. ... to perpetuate the chronic process by their marked increased accumulation in the synovial lining of the inflamed joint and their ability to produce numer...

Ngày tải lên: 09/08/2014, 14:22

... Research & Therapy, in which they describe cytokine patterns of inflamed joints from patients with Behçet’s disease (BD). The authors show that neutrophils and T lymphocytes are involved in a Th1-skewed inflammatory ... terminated while TNF blockage was continued. Cytokines were evaluated in the resected colon by analyzing mRNA expression levels of cytokine genes as previo...

Ngày tải lên: 09/08/2014, 14:22

... injury in the remaining 9 (30%) patients. The mechanism of injury was gunshot in 16 patients, stabbing in 4, falling in 1 (extraluminal injury), and foreign body in 9 (endoluminal injuries). The ... perforation [11,12]. The goal of treatment must be to prevent further soilage from the perforation, to eliminate infection pro- duced by soilage, to restore the integrit...

Ngày tải lên: 10/08/2014, 09:22

... for localizing the site of pathology and determining the severity of the condition, it does have limitations. Electrodiagnostic studies are uninformative about structures surrounding the nerve ... history of degenerative disc disease and the nature of the injury, but an MRI and CT myelogram of the cervical spine showed no changes compared to his previous cervical spine...

Ngày tải lên: 10/08/2014, 10:20

... demyelinating plaque. The presence of alternating rings of myelin preservation or remyelination and myelin loss, consistent with demyelination, corre- sponds to the concentric type of demyelination, ... rapidly progressive course, sometimes fatal. Histologically, it is characterized by a large lesion consisting of rings of demyelination alternating with rings of intact mye...

Ngày tải lên: 10/08/2014, 23:21

... pretreated with two lines of platinum-containing chemotherapy with no evidence of response; a response was only observed upon treatment with cisplatin along with cetuximab. We do not know whether the ... interests The authors declare that they have no competing interests. Authors' contributions SG was involved in the conceptual design of this study, in the clini...

Ngày tải lên: 11/08/2014, 21:22