Báo cáo y học: "Novel biomarkers in critical care: utility or futility" pot

... understanding) of many of these novel biomarkers has been reinforced by predictable changes in their levels upon specific, clinically relevant and successful interventions [9,10]. Again, this is a major challenge ... medicine and the dangers of extrapolating population- centred, relatively uncomplicated, limited, single-organ patho- physiology to the critically ill patient. However, defin...

Ngày tải lên: 13/08/2014, 08:20

... particularly in technology- oriented areas such as critical care. Electronic patient records require a major commitment by the institution, in hardware, software, training, and support. In many places, bedside ... Stewart Mount Sinai Hospital, University of Toronto, Toronto, Canada. Correspondence: Stephen E Lapinsky, stephen.lapinsky@utoronto.ca The rapid development of computing tec...

Ngày tải lên: 12/08/2014, 18:21

... stimulant descending inhibitory neural pathways sensory neurones 5-HT, 5-hydroxytryptamine. Table 2 Summary of studies of gastrointestinal promotility drugs Number Population Study design of studies ... of an intrinsic cholinergic pathway smooth muscle Cisapride Activates 5-HT 4 Motility Initiates peristaltic reflex by simultaneously activating ascending excitatory and receptors on intrinsic...

Ngày tải lên: 12/08/2014, 19:21

... efficiency of healthcare systems according to changes in disease incidence or outcome, and for planning research studies according to the characteristics of the disease. Large-scale longitudinal ... populations and different risk factors for disease. More broadly, when epidemiology studies are conducted they longitudinally create the ability to examine healthcare quality and effectiveness...

Ngày tải lên: 12/08/2014, 23:23

Ngày tải lên: 13/08/2014, 20:22

... infections are rare in fully industrial- ized countries with more or less intact health care systems but are frequent in countries with emerging mar- kets or in the developing world. In the view of ... HOPE-Project. Author Details 1 Institute for Virology, Helmholtz Zentrum Munich, Munich, Germany, 2 Institute for Virology, University Hospital Essen, Essen, Germany, 3 Institute...

Ngày tải lên: 12/08/2014, 04:20

... signals being influenced by therapeutic meas- ures as much as being markers of underlying disease. This is an important consideration in evaluating TDI as a prognostic indicator in the critically ill. ... ICU admission. It is likely that the results would be influenced by timing of echocardiography relative to initiation and progress of therapy. This study incorporated a secondary aim of...

Ngày tải lên: 13/08/2014, 08:20

Ngày tải lên: 13/08/2014, 10:20

... overlapping nature of the presenting illnesses are amongst the inherent difficulties. Influential studies in this population therefore increasingly involve multicentre, collaborative efforts using rigorously ... of conducting high-quality clinical studies in the critically ill population is widely recognised. Heterogeneity in patient populations and clinical practice, diagnostic uncerta...

Ngày tải lên: 13/08/2014, 11:22

... suggesting that bacteria were not pathogenic [8,9]. The bacterial allergy theory presents an interesting irony in the history of immuno- therapy when viewed in light of the hygiene hypothesis. The ... reaction; RSV: respiratory syncy- tial virus; TLR: toll like receptor; TNF: tumor necrosis fac- tor; IL: interleukin; SNP: single nucleotide polymorphism; VDR: vitamin D receptor; IFN: inter...

Ngày tải lên: 13/08/2014, 13:22