Báo cáo y học: "Factor VII and the brain: time to get this research done" potx

... reduce the potential for secondary injury. To CommentaryFactor VII and the brain: time to get this research done!Richard P DuttonUniversity of Maryland School of Medicine, R Adams Cowley Shock ... prevent secondary injury from hypoxia, hypotension,hyperglycemia, hyperthermia, electrolyte imbalances, orprogressive cerebral edema. This task is especially complexin the polytraumatized patient, ... end-points.Although none of these are significant in themselves, they arecollectively significant in that they all vary in the same way,favoring FVIIa.Traumatic brain injury (TBI) is the most common cause...

Báo cáo y học: "Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report" potx

... pulmonary and hepatic toxicity secondary to nitrofurantoin: a case reportAdrian F Peall* and Aidan HodgesAddress: Respiratory Department, Hawke's Bay Hospital, Hastings, New ZealandEmail: ... breathlessness continued to worsen after this initial course of therapy and she was admitted for fur-ther investigation and treatment.A review of her history in the months prior to this acutedeterioration ... evidence to sup-port their use in addition to withdrawal of nitrofurantoin[5]. Interestingly this woman's symptoms did notimprove in response to the short course of prednisoneprescribed by...

Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"

... with the need to explain to their clients that it is not necessary, for example, to give away one’s cat during pregnancy and that if they follow a few very simple “rules”, liv-ing with their ... represent any risk for infection with Toxoplasma gondii. Cats are the definitive host of T. gondii; they are the only animals that pass oocysts in their feces. They become infected by eating ... rodents, birds, or other small animals. Once oocysts are shed, they re-quire 1 to 5 days to sporulate and become infective. Cats pass oocysts for only 2 to 3 weeks following primary infection. Mature...

Báo cáo y học: "Epidemiology, costs, and the economic burden of fibromyalgia" pptx

... ImpactQuestionnaire, the Brief Pain Inventory, and the EuropeanQuality of Life five-item questionnaire.For many years there has been agreement about the preva-lence of FM being approximately 2 to 3%. The most ... estimates for populations in othercountries. The alarming results highlight the urgent need both formore research (including pathophysiology and epidemiology) and for the acceptance of emerging ... ankylosingspondylitis – the latter amount was calculated prior to the approval of biologicals for the treatment of ankylosingspondylitis [8]. The study from Sicras-Mainar and colleagues is the firstcalculation...

Báo cáo y học: " Evolution, ecology and the engineered organism: lessons for synthetic biology" ppt

... intractable systems: the complete genome of Mycoplasma mycoides was transferred into yeast, altered using yeast genetic tools, and then transplanted back into a Mycoplasma cell to yield a new M. mycoides ... ecologies. This cycle creates a diverse array of functions that can be used in synthetic designs. Individual functions may be combined and evolved in the laboratory to create new synthetic systems ... evolutionary and ecological concepts into synthetic biology research and practice (Figure 1).Lesson 1: Evolution is a source of functional diversity and modularityOne of the central goals of synthetic...

Báo cáo y học: "DNA transposons and the role of recombination in mutation accumulation in Daphnia pulex" pdf

... accumulation to detect. This analysis represents the first multi-element comparisonin a cyclic al parthenogen and crustacean and suggestsTE dynamics in this species vary based on family size and may be ... and stored in tissue culture plateswith 5 to 10 ml H20 per well at 4°C. This occurred typi-cally 4 to 5 days after asexually produced young hadbeen born and transferred to a new beaker to ... location on the trace file in multiple lineagesare presumed to be ancestral (that is, they were presentin the single individual ancestor to the experimentallines, and may only be lost over time, ...

Báo cáo y học: " Dosage compensation and the global re-balancing of aneuploid genomes" ppt

... denomi-nators. First, they all adapt factors and mechanisms, which are already involved in other regulatory processes, for the compensation task by harnessing them in a new molecular context. Furthermore, ... can no longer trigger the apoptotic pathway, yet its role in the cell-cycle checkpoint is not impaired. Evidently, the substrate speciﬁcity of human MOF and the physiological processes in ... KAT8, lysine acetyltransferase 8), a histone acetyltransferase with speciﬁcity for lysine 16 in the amino-terminal tail of histone 4 (H4K16ac). Acetylation of this residue is known to reduce...

Báo cáo y học: "Mechanical ventilation and the total artificial heart: optimal ventilator trigger to avoid post-operative autocycling - a case series and literature review" pdf

... pressure at the expense of altered flow, ultimately leading to autocyclingin the case of a flow trigger. Given the frequency of auto-cycling in the ICU, this information may be applicable to other ... pressuremaintenance at the expense of a change in flow, whichmay then trigger an autocycled breath if timed correctly.ConclusionIn summary, autocycling of the mechanical ventilatoroccurred in 50% ... any autocycling noted, and another patient waskept on a pressure trigger of 2 cm H2O until extubationwithout any autocycling recorded.Five of the 10 patients developed autocycling of the ventilator,...

Báo cáo y học: " Cancer, inflammation and the AT1 and AT2 receptor" ppt

... director of Perses BiosystemsLtd. The goals of the company are to drive laboratory and clinical research into the role of angiotensin receptors inSystems view of the AT receptor roleFigure 4Systems ... pro-inflammatory effect, promoting the expression of many pro-inflamma-tory mediators, such as cytokines, chemokines and adhesion molecules through the activation of signalling pathways. The influx, ... hypoxic pul-monary hypertension [41]. Hypoxia has been shown to strongly induce the expression of AT1b but not AT1a. The expression of AT2 is believed to protect the cell fromapoptosis and this...

Báo cáo y học: "Complex systems and the technology of variability analysis" ppsx

... circadian rhythm, VLF is affected bytemperature regulation and humoral systems, LF is sensitive to cardiac sympathetic and parasympathetic nerve activity, and HF is synchronized to respiratory rhythms, ... factor in the assumptions inherent to this calculation,namely stationarity and periodicity. Note that the square of the contribution of each frequency is the power of that frequency to the total ... pleiotropy and redundancy. Complex sys-tems have properties that cannot wholly be understood byunderstanding the parts of the system [1]. The properties of the system are distinct from the properties...

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