Báo cáo y học: "Prostaglandin I2 enhances cough reflex sensitivity to capsaicin in the asthmatic airway" pps

... [20,21]. Although cysteinyl leukotrienes (cLTs) play an important role in bronchomotor tone of the asthmatic airway, their role in cough reflex sensitivity is controversial [19,22]. These findings indicate ... with the clearance of the tracheobronchial mucus, may occur via increased cough reflex sensitivity. Inflam- matory mediators such as prostaglandins may adjust th...

Ngày tải lên: 13/08/2014, 08:20

... given the option to continue their study medications under the care of one of the study physicians or another psychiatrist at POSA. Those wishing to discontinue the study medica- tions at the end ... if the anxiolytic effect of risperidone is secondary to a concomitant reduction in symptoms of depression. We attempted to examine the effect of baseline depressive sympto...

Ngày tải lên: 11/08/2014, 17:20

... IU/mL) led to a small but significant increase in cytokine production (Figure 1d). Combination of glucose and insulin on cytokine release To determine whether the hyperglycemic effect on cytokine release ... only viable cells are able to produce and release cytokines. Cytokines are not stored in intracellular compart- ments but rather are newly synthesized and released in respon...

Ngày tải lên: 13/08/2014, 11:22

... noted in sonography. During laparoscopy, uterine rupture with massive bleeding was detected; therefore, total abdominal hysterectomy was performed. The patient was discharged without any complications. ... appropriate treatment. The first laparoscopic surgery during pregnancy was cholecystectomy, performed in 1991 [14]. Thereafter, laparoscopy has been widely used in pregnant...

Ngày tải lên: 25/10/2012, 10:56

... arthritis or other types of pain) or is unwilling to stop taking other medications for the treatment of OA Any other condition that, in the opinion of the investigator, would adversely affect the subject's ... intensity and to record therapies in the study diary Subject agrees not to start any new therapies for OA during the course of the study Able to give...

Ngày tải lên: 26/10/2012, 09:48

... genes of the A201A biosyn- thetic pathway, may be related to their counterparts of the puromycin and hygromycin A biosynthetic pathways, respectively. The puromycin biosynthetic gene cluster (pur)from S. ... type III PKSs, which lack this domain, is scant. This domain promotes the binding of the acyl-CoA initiation unit to the ketosynthetase domain of the PKSs for polyketide...

Ngày tải lên: 21/02/2014, 01:21

... level only after 60 min (Fig. 1). Pyp1p and Pyp2p phosphatases appear to play a key role in the dephosphorylation of the osmotic stress-activated Sty1p [20]. Interestingly, however, the Sty1p activation ... induced a strong activation of Sty1p kinase. In this context, we tried to estimate the levels of Sty1p phosphorylation in strain TS-2 (wak1 – , Sty1p-Ha6H) to determine...

Ngày tải lên: 08/03/2014, 09:20

... ability t o rescue dystrobrevin (dyb-1) mutations in C. elegans. The deletions affecting the second helix of the D yb-1 coiled-coil domain abolished the binding of dystrobrevin to dystrophin both in ... dystrophin and dystrobrevin are able t o bind to each other in vitro [18] in the same way as their mammalian counterparts [12], and they also bind to syntrophin [18]. dy...

Ngày tải lên: 08/03/2014, 23:20

... probably increases the affinity for Ca 21 of EF-A to result in the second Ca 21 -binding to EF-A. It remained uncertain whether the binding of Ca 21 to EF-B contributes to this increase in the Ca 21 -affinity ... of the change in the a helix content was attained by binding of two Ca 21 . Interestingly, in the mutants which have only three Ca 21 -binding sites, the...

Ngày tải lên: 24/03/2014, 04:21

... that 2-deoxygalactose is toxic to wild-type yeast strains that constitutively express galactokinase, due to the accumula- tion of 2-deoxygalactose-1-phosphate [40]. Growth of a wild-type strain bearing the CYC1::GAL1 ... Spring Harbor Laboratory, Cold Spring Harbor. New York. 40. Platt, T. (1984) Toxicity of 2-deoxygalactose to Saccharomyces cerevisiae cells constitutively synthesis...

Ngày tải lên: 31/03/2014, 08:20