USMLE ROAD MAP BIOCHEMISTRY – PART 6 pot

... impairs metabolism of medium- chain (C6–C12) fatty acids. – The C6–C12 fatty acids and their esters accumulate in tissues to cause toxicity. – Spillover of C6–C10 acylcarnitine species into the ... possible problems: – Hepatic dysfunction leading to decreased bile acid synthesis. – Severe ileal disease leading to malabsorption of bile salts. – Obstruction of the biliary tr...

Ngày tải lên: 13/08/2014, 07:20

... portion of fructose to be excreted in the urine. 86 USMLE Road Map: Biochemistry N CLINICAL CORRELATION CLINICAL CORRELATION 102 USMLE Road Map: Biochemistry N 5. The answer is A. This patient ... agents. 98 USMLE Road Map: Biochemistry N Table 7–1 . Stoichiometry of ATP generation from one glucose molecule. a NADH FADH 2 ATP Cytoplasm Glucose → glucose 6- phosphate...

Ngày tải lên: 13/08/2014, 07:20

... approxi- mately 100 to 1, what would be the pH in the muscle cells? A. 1. 86 B. 2. 86 C. 3. 86 D. 4. 86 E. 5. 86 6 USMLE Road Map: Biochemistry N CLINICAL CORRELATION Copyright © 2007 by The McGraw-Hill ... otherwise. DOI: 10.10 36/ 0071442057 USING THE USMLE ROAD MAP SERIES FOR SUCCESSFUL REVIEW What is the Road Map Series? Short of having your own personal tutor, the...

Ngày tải lên: 13/08/2014, 07:20

... frequently lethal soon after birth. 14 USMLE Road Map: Biochemistry N CLINICAL CORRELATION CLINICAL CORRELATION CLINICAL CORRELATION 34 USMLE Road Map: Biochemistry N V max V i 1 2 V max 0 0 [S] Positive ... inhibit the enzyme acetylcholinesterase. – This hydrolase normally breaks down the neurotransmitter acetylcholine within nerve synapses. 28 USMLE Road Map: Bioche...

Ngày tải lên: 13/08/2014, 07:20

... composition. 40 USMLE Road Map: Biochemistry N Steroid nucleus CH 3 HO AB CD CH 3 CH 3 CH 2 CH 2 CH 2 CH 3 CH 3 CH CH 2322 24 27 26 25 21 2 1 3 4 5 6 7 8 14 15 16 20 17 11 19 10 9 12 18 13 Figure 4–3 . Structure ... high relative to the extracellular fluid (Figure 4–7 ). 46 USMLE Road Map: Biochemistry N OUT IN Transport Glucose Binding RecoveryRelease Figure 4 6 . M...

Ngày tải lên: 13/08/2014, 07:20

... to ribose 5-phosphate (Figure 6 3 ). a. Ribose 5-phosphate provides the ribose and deoxyribose sugars found in nucleotides. 76 USMLE Road Map: Biochemistry N Table 6 1 . Energy yield in anaerobic ... body. 78 USMLE Road Map: Biochemistry N Table 6 2 . Regulators of enzyme activity in glucose metabolism. Enzyme Activators Inhibitors Hexokinase Glucose 6- phosphate Phosphofruct...

Ngày tải lên: 13/08/2014, 07:20

... is most likely defective? A. Base excision repair B. Mismatch repair 164 USMLE Road Map: Biochemistry N 2. The tRNAs are 6 5–1 10 nucleotides long and their backbones fold back to allow for intramolecular ... anticodon is frequently inosine (I) to provide this flexibility in hydrogen bonding. 166 USMLE Road Map: Biochemistry N A. FMR1 (Fragile X) B. XP-A (Xeroderma pigment...

Ngày tải lên: 13/08/2014, 07:20

... representing affected persons in this pedigree indicate age of diagnosis. 1 96 USMLE Road Map: Biochemistry N I II III 67 61 37 51 57 54 44 43 38 4. What type of molecular phenomenon is most likely ... with Tay-Sachs disease exhibit hypotonia (poor muscle tone) and progressive neurologic symptoms, including blindness and mental retardation. 1 86 USMLE Road Map: Biochemistry...

Ngày tải lên: 13/08/2014, 07:20

... problems/solutions, 6 6 6 9 diet and nutritional needs, 5 2–5 4 glucose homeostasis, 5 6 5 8, 57f metabolism (fasting state), 6 1 6 3, 62 f metabolism (fed state), 5 8 6 1, 59f, 60 f metabolism (starvation), 6 3 6 4, 64 f regulation ... (splicing), 16 3–1 64 , 163 f structure, 16 0–1 61 transcription, 16 1–1 62 , 162 f example of anticipation, 193 Tumor necrosis fact...

Ngày tải lên: 13/08/2014, 07:20

... form (Figure 3 9 6 A to 3 9 6 C). The product of the cro gene, the 66 -amino-acid, 9kDa Cro protein, has a single domain but also binds the operator DNA more tightly as a dimer (Figure 3 9 6 D). The Cro ... to ch39.qxd 3/ 16/ 04 11:04 AM Page 380 REGULATION OF GENE EXPRESSION /381 Amino acids 132 – 2 36 COOH ABCD Cro O R 1O R 3 COOH NH 2 NH 2 COOH COOH NH 2 NH 2 Amino acids 1 – 92 C...

Ngày tải lên: 13/08/2014, 07:20