... frequently lethal soon after birth.
14 USMLE Road Map: Biochemistry
N
CLINICAL
CORRELATION
CLINICAL
CORRELATION
CLINICAL
CORRELATION
34 USMLE Road Map: Biochemistry
N
V
max
V
i
1
2
V
max
0
0
[S]
Positive
... K
m
(Point A in Figure 3 3 ), then [S] + K
m
≅ K
m
, con-
ditions where v is directly proportional to [S] and is low relative to V
max
.
3. When [S] = K
m
(Point B in Fig...
... otherwise.
DOI: 10.1 036 /0071442057
USING THE
USMLE ROAD MAP SERIES
FOR SUCCESSFUL REVIEW
What is the Road Map Series?
Short of having your own personal tutor, the USMLE Road Map Series is the ...
N
LANGE
USMLE
ROAD MAP
BIOCHEMISTRY
RICHARD G. MACDONALD
Department of Biochemistry and Molecular Biology
University of Nebraska Medical Center
Omaha, Nebraska
WILLIAM...
... to ribose
5-phosphate (Figure 6 3 ).
a. Ribose 5-phosphate provides the ribose and deoxyribose sugars found in
nucleotides.
76 USMLE Road Map: Biochemistry
N
Table 6–1 . Energy yield in anaerobic ... to oxaloacetate occurs in the mitochondria (Fig-
ure 6–7 ).
82 USMLE Road Map: Biochemistry
N
F. Conversion of 1 ,3- bisphosphoglycerate to 3- phosphoglycerate represents an
ox...
... portion of fructose to be excreted in the urine.
86 USMLE Road Map: Biochemistry
N
CLINICAL
CORRELATION
CLINICAL
CORRELATION
102 USMLE Road Map: Biochemistry
N
5. The answer is A. This patient exhibits ... double bonds that is the pre-
cursor for several other omega -3 ( -3) fatty acids.
Chapter 8: Lipid Metabolism 105
N
88 USMLE Road Map: Biochemistry
N
4. Which of the...
... possible
problems:
– Hepatic dysfunction leading to decreased bile acid synthesis.
– Severe ileal disease leading to malabsorption of bile salts.
– Obstruction of the biliary tract.
116 USMLE Road Map: Biochemistry
N
No ... the endoplasmic reticulum.
108 USMLE Road Map: Biochemistry
N
CO
2
Malonyl CoA
CoA
FAS
O
S
CCH
3
O
S
C COOCH
2
O
S
C CH
2
CH
3
O
C
FAS
SH
Fou...
... 12).
162 USMLE Road Map: Biochemistry
N
RNA Pol II
Holoenzyme
Non-template
DNA strand
Template
DNA strand Topoisomerase
Nascent hnRNA
5'
3& apos;
Synthesis
Topoisomerase
Figure 1 1 3 . The prokaryotic ... the A site.
172 USMLE Road Map: Biochemistry
N
Release of
empty tRNA
Translocation
Peptidyl
transfer
(n+1)
(n)
EF + GDP + P
i
Aminoacyl-tRNA
binding
Ternary
complex
EF
Fi...
... retardation.
186 USMLE Road Map: Biochemistry
N
Male
Female
Affected
Unaffected
Deceased
Obligate carrier
Marriage or mating
Consanguinity
Proband
1 234
1 234 5
12 3
1 23
4567
I
II
III
IV
,
,
,
,
Figure 1 3 1 . ... or 3. 9%
q =
A
1
2500
= 20.0004 = 0.02, and: p = 1- q = 1- 0.02 = 0.98
194 USMLE Road Map: Biochemistry
N
Males
A
(p)
A
(p)
a
(q)
a
(q)
AA
(p
2
)
Aa
(pq)
A
(pq)...