Harper’s Illustrated Biochemistry - Part 5 pptx
... 297 HN 2 H 7 5 Formylglycinamidin e ribosyl -5 - phosphate R- 5- P (VI) 3 6 ATP, Mg H 2 O H 2 O H 2 O 2 + Ring closure 7 R- 5- P Aminoimidazole ribosyl -5 - phosphate (VII) N 2 H 8 OOC CO 2 C CH R- 5- P 2 H N N Aminoimidazole carboxylate ... ribosyl -5 - phosphate (IX) O 6 5 3 4 1 OOC – C 2 HC OOC – C N C C N H H 10 H 4 folate C CH N N Aminoimidazole carboxamide ribosyl -5 - phos...
Ngày tải lên: 13/08/2014, 07:20
... hemolymph. 1 O- - D -Glucopyranosyl-(1 → 1 )- - D -glucopyranoside. HO H HOCH 2 H OH H H OH O H O- - D-Glucopyranosyl-(1 → 4 )- -D-glucopyranose O- - D-Glucopyranosyl-(1 → 2 )- -D-fructofuranoside 3 5 6 4 H HOCH 2 H OH H H OH O OH H 5 6 4 O Maltose ** 11 232 HO H HOCH 2 H OH H H OH O H 3 5 6 4 O Sucrose 1 2 * HOCH 2 1 O OH ... + ⋅ + Substrate A-H A-OH P 450 -A-H Fe 3...
Ngày tải lên: 13/08/2014, 07:20
... (6-phospho- fructo-2-kinase/fructose-2,6-bisphosphatase). (PFK-1, phosphofructokinase-1 [6-phosphofructo-1-kinase]; F-1,6-Pase, fructose-1,6-bisphosphatase. Arrows with wavy shafts indicate allosteric effects.) fructose-1,6-bisphosphatase. ... 6-phosphate H 2 O P i GLUCONEOGENESIS GLYCOLYSIS Glycogen Glucose Pyruvate Citrate F-1,6-Pase PROTEIN PHOSPHATASE-2 Inactive F-2,6-Pase Active PFK-2 A...
Ngày tải lên: 13/08/2014, 07:20
Harper’s Illustrated Biochemistry - Part 6 potx
... properties. ch37.qxd 3/16/04 11:02 AM Page 355 386 / CHAPTER 39 HMGI-Y ATF-2 cJun NF-κB IRF(IRF3/7) HMG PRDIV PRDII NRDI HMG HMG HMG PRDI-III IRF3 HMGI HMGI HMGI HMGI ATF-2 cJun IRF7 NF-κB Figure 39–9. Formation ... the in- creased number of subunits, eukaryotic pol II differs from its prokaryotic counterpart in that it has a series of heptad repeats with consensus sequence Tyr-Ser-Pro- Thr-...
Ngày tải lên: 13/08/2014, 07:20
Harper’s Illustrated Biochemistry - Part 7 ppsx
... ENZYME ANGIOTENSINASES Asp-Arg-Val-Tyr- I le-His-Pro-Phe-His-Leu-Leu (~400 more amino acids) Asp-Arg-Val-Tyr- I le-His-Pro-Phe-His-Leu Asp-Arg-Val-Tyr- I le-His-Pro-Phe Arg-Val-Tyr- I le-His-Pro-Phe Figure ... α-Hydroxylase24-Hydroxylase HO HO 27 25 24 26 HO CH 2 CH 2 OH OH 7-Dehydrocholesterol 1, 25( OH) 2 -D 3 24, 25( OH) 2 -D 3 1,24, 25( OH) 3 -D 3 2 5- Hydroxycholecalciferol ( 25[ OH]-...
Ngày tải lên: 13/08/2014, 07:20
Harper’s Illustrated Biochemistry - Part 9 pps
... polysaccharides with a component desig- nated C3b. ch50.qxd 2/14/2003 11:47 AM Page 59 6 MUSCLE & THE CYTOSKELETON / 55 9 G-actin F-actin Troponin TpC 35. 5 nm 38 .5 nm 6–7 nm The assembled thin filament TpI TpT Tropomyosin Figure ... filament called F-actin (Figure 49–3). The F-actin fiber is 6–7 nm thick and has a pitch or repeat- ing structure every 35. 5 nm. ch49.qxd 2/14/2003 10...
Ngày tải lên: 13/08/2014, 07:20
Harper’s Illustrated Biochemistry Twenty-Eighth Edition_2 docx
... hydrolases, including α-neuraminidase, β-galactosidase, β-hexosaminidase, - and β-mannosidases, α-N-acetylgalactosaminidase, α-fucosidase, endo- β-N-acetyl- glucosaminidase, and aspartylglucosaminidase. ... using Dol-P-Man as the donor. Dol-P-Man is formed by the following reaction: Dol-P + GDP-Man → Dol-P-Man + GDP 4. Finally, the three peripheral glucose residues are donated by Dol-...
Ngày tải lên: 22/03/2014, 21:20
Harper’s Illustrated Biochemistry Twenty-Eighth Edition_1 ppt
... well-ordered crystals. To establish appropriate Forkhead transcription factor DNA-bindingNLS Pr-Pr 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Reg RegCatalysis Pr-Pr RegCatalysis Pr-Pr Pr-Pr Catalysis Catalysis Phenylalanine ... hydrolyze pep- tide bonds and generate peptides with as few as two or three amino acids. Each peptide was reacted with 1- uoro-2,4-dini- IEF SDS PAGE 01=...
Ngày tải lên: 22/03/2014, 21:20
harper's illustrated biochemistry - robert k. murray, darryl k. granner, peter a. mayes, victor w. rodwell
... / CHAPTER 5 N 280 3 45 30 55 50 330 350 90 230 2 45 260 258 300 310 320 220 110 170 1 25 120 2 05 1 45 150 1 85 C 377 70 15 80 Figure 5 6. Examples of tertiary structure of pro- teins. Top: The enzyme ... Cleaved CNBr Met-X Trypsin Lys-X and Arg-X Chymotrypsin Hydrophobic amino acid-X Endoproteinase Lys-C Lys-X Endoproteinase Arg-C Arg-X Endoproteinase Asp-N X-Asp V8 protea...
Ngày tải lên: 08/04/2014, 12:42
CLINICIAN’S POCKET REFERENCE - PART 5 pptx
... (Vioxx) PO 2–3 h 24 h 12 .5 mg 50 mg OPIOID Codeine IM 0. 25 0 .5 h 4–6 h 15 mg 60 mg PO 0. 25 1 h 3–4 h 15 mg 60 mg Fentanyl IV 1.7–2.3 h 1 h 1–1 .5 µg/kg 150 TD 1.7–2.3 h 1 h 25 mg/h 100 µg/h Meperidine ... µg/h Meperidine (Demorol) PO 0 .5 1 h 2–3 h 1–1 .5 mg/kg 50 –100 mg IM 0.12–0 .5 h 2–4 h 1–1 .5 mg/kg 50 –100 mg Methadone (Dolophine) PO 0 .5 1 h 4–8 h 2 .5 10 mg 160...
Ngày tải lên: 19/06/2014, 15:20