DNA Methylation: Basic Mechanisms - Part 10 pot

... islands of non-meth y lated, CpG-rich DNA. C ell 40: 9 1– 99 Bir d AP, Taggart MH, Nic h o ll s RD, Higgs DR (1987) Non-met h y l ate d CpG-ric h is- l an d satt h e h uman a l p h a-g l o b u l in l ocus: ... 79, 92 , 101 A RBP 35 a rc h egoniates 9 9 A RGONAUTE prote i n8 5 A TRX- h omo l ogy d omain 187, 19 2–1 94 a ut i sm 36 au xin 75 5-aza- 2  deox y c y tidine 18 7 5-aza-d C 18 7...

Ngày tải lên: 13/08/2014, 07:20

... non-5  -CG -3  C-residues were never meth y lated. Around exon 1 of the S NRPN g ene, more t h an 96% o f t h e23 5  - CG - 3  - d inuc l eoti d es were met h y l ate d on t h emater - na l c h romosome, ... Gene s Th e5  - CG - 3  -rich promoter re g ion of the DNA- dependent RNA pol y merase I (rDNA) g enes was ana ly ze df or t h e presence o f 5-mC nuc l...

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... BF, Belozersk y AN, Kokurina NA, Kadirova DX (1968) 5-Meth y lc y tosine an d 6-met h y l amino-purine in b acteria l DNA. Nature 218 :106 6 106 7 W aa l wij k C, F l ave ll RA (1978) MspI, an isosc h izomer ... aci d o f t h etu b erc l e b aci ll us . Su b sequent ly , 5-mC h a d a b ioc h emica lf uture as 5- hyd rox y met hyl -C ( 5- h m-C) in the DNA of the T-even bacterio pha g...

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... approximatel y 100 -amino-acid-containin g tran- scriptiona l repression d omain (TRD) in t h emi ddl eo f t h e protein h as b een shown to be critical for transcriptio nal silencin g (Nan et al. 1997). Apart ... interacting d omain; C XX C ,Cys-ric hd omain ; ( E ) 1 2 , G l u repea t; ( GR ) 11 , G l y-Arg repeat; MBD , met h y l -CpG- b in d ing d omain ; Hh H-GPD,DN A N-Gl y cos y lase...

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... ompose d o f small g ene-rich re g ions intermixed with 5- to 200-kb blocks of repetitiv e DNA. The repetitive DNA blocks are usuall y meth y lated at 5  - CG -3  a n d5  - C NG-3  c ytosines in ... 2003). The DNA meth y lase inhibitors 5-azaC y t and 5-aza- 2  -deox y c y tidine inhib - ite d a d ventitious s h oot in d uction in Petun i a l ea f cu l tures. C y...

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... meth y ltransferases in RNA-directed DNA meth y la- tion. C urr Biol 13:2212–221 7 Casti lh oA,NevesN,Ru fi ni-Castig l ione M, Viegas W, Hes l op-Harrison JS (1999) 5- Met h y l cytosine d istri b ution ... DX (1968) 5-Met h y l cytosine and 6-meth y laminopurine in bacterial DNA. Nature 218 :106 6 106 7 V an y us h in BF, T k ac h eva SG, Be l ozers ky AN (1970) Rare b ases in anima l...

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... Heteroc h romatin f ormatio n SUMO-1 N-termina l Sma ll u b iquitin-re l ate d protein Ubc9 N-terminal SUMO-1 E2 con j u g atin g enz y me PIAS1 N-terminal SUMO-1 E3 li g ase PIA S x α N-termina l SUMO-1 E3 l igase Dnmt3L ... RA R β . PML-RAR-induced re p ression of RAR β t ranscription was partia ll yre l ease db y 5-aza- d C, in d icating t h at DNA met h y - lation contributes to the...

Ngày tải lên: 13/08/2014, 07:20

... of DNA- (C y tos i ne-C5)-MTase s A ll DNA MTases use t h e coenz y m e S- a d enos yl- l - met h ionine ( A d oMet ) as t he s ource f or t h e met h y l group b eing trans f erre d to t h eDNA b ases. ... Je l tsc h 2002 ) . 2 .1 Reaction Mechanism of DNA- (Cytosine-C5)-MTase s The reaction mechanism of c y tosine-C5 meth y lation was uncovered for th e prokar y otic DNA- (c y tosi...

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... t h at reco g- nised hemi-meth y lated DNA at the replication fork and meth y lated the new s tran d .T h is enz y me wou ld not reco g nise non-met hyl ate d DN A. We a l so pro - posed, followin g Scarano ... (2004) SIRPH anal y sis: SNuPE with IP-RP-HPLCfor quantitativemeasure- ments of DNA meth y lation at specific CpG sites. Methods Mol Biol 287:195–20 5 El -Maarri O, Her b iniaux...

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... repair b y d ip l oi d h uman fibroblasts on the kinds and locations of mutation s induced b y (± )-7 b,8a - d ih y drox y -9 a,10a-epox y -7 ,8,9 ,1 0- tetrah y drobenzo[a]p y rene in the codin g re g ion of t h e HPRT gene. ... is DNA repair. Th e p resence o f 5-met h y l cytosine may a ff ect t h e sequence- d epen d ent repair of DNA adducts. A 5-meth y lc y tosine base at...

Ngày tải lên: 13/08/2014, 07:20