DNA Methylation: Basic Mechanisms - Part 3 pptx
DNA Methylation: Basic Mechanisms - Part 3 pptx
... ompose d o f small g ene-rich re g ions intermixed with 5- to 200-kb blocks of repetitiv e DNA. The repetitive DNA blocks are usuall y meth y lated at 5 - CG -3 a n d5 - C NG -3 c ytosines in ... 83 2.6 RNA-Directed DNA Meth y lation 86 2.7 Biolo g ical Role of C y tosine DNA Meth y lation 9 0 3 Adenine DNA Meth y latio n 9 7 3. 1 N 6 -Met h y l a d eni...
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DNA Methylation: Basic Mechanisms - Part 1 pptx
... the ecolo gy of in - tra g enomic parasites. Trends Genet 13: 335 34 0 The Almost-For g otten Fifth Nucleotide in DNA: An Introductio n 1 1 A conventiona l review artic l e on DNA met h y l ationorononeo f its ... w h ic h c l eaves b ot h unmet h y l ate d an d met h y l ate d HpaII sites. Nuc l eic Aci d s Res 5 :32 31 32 36 W i ll is DB, Grano ff A (1980) Frog virus 3 DNA is h e...
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DNA Methylation: Basic Mechanisms - Part 2 ppsx
... Mo l Bio l 297:2 93 30 0 Martinowic h K, Hattori D, Wu H, Fouse S, He F, Hu Y, Fan G, Sun YE (20 03) DNA meth y lation-related chromatin remodelin g in activit y -dependent BDNF g ene re g - ulation. S cience 30 2:8 9 0–8 9 3 Matarazzo ... Deri j ck AA, Braunschwei g U, Perez-Bur g os L, Kubicek S, Chen T, Li E, Jenuwein T, Peters AH (20 03) Suv39h-mediated histone H3 l y sine 9 met...
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DNA Methylation: Basic Mechanisms - Part 4 ppsx
... 128: 133 – 138 Lawrence RJ, Pikaard CS (20 03) Trans g ene-induced RNA interference: a strate gy fo r overcomin gg ene redundanc y in pol y ploids to g enerate loss-of-function muta - tions. Plant J 36 :114–12 1 Lawrence ... Unmeth y latedCellularDNA 134 2.2 .3 Suppression of the Frequenc y of 5 -CG - 3 D inuc l eoti d es i nt h e Genomes o f t h eSma ll Eu k aryoticViruses...
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DNA Methylation: Basic Mechanisms - Part 5 pot
... non-5 -CG -3 C-residues were never meth y lated. Around exon 1 of the S NRPN g ene, more t h an 96% o f t h e 23 5 - CG - 3 - d inuc l eoti d es were met h y l ate d on t h emater - na l c h romosome, ... The C-residue meth y la - t ion o f two A l uI sites (5 -AGC T - 3 ) d ownstream f rom t h eTATA b ox h a d no effect on promoter activit y . How...
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DNA Methylation: Basic Mechanisms - Part 6 pps
... Droso p hila a n d m amma l ian d eve l o p ment(Kunert et a l . 20 03; M. O k ano an d E. Li, un p u bl is h e d results ). 2 .3 D nmt 3 The Dnmt3 family has three members: Dnmt3a, Dnmt3b, and Dnmt3L (Dnmt3-like). Dnmt3L, which shows sequence ... silencin g Dnmt3a C-terminal DNA meth y ltransferas e Dnmt3b C-terminal DNA meth y ltransferase D nmt3a an d Dnmt3 b are very simi l ar in...
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DNA Methylation: Basic Mechanisms - Part 7 docx
... (20 03) T h e eu- k aryotic DNMT2 genes enco d e a new c l ass o f cytosine-5 DNA met h y l trans f erases. JBio l C h em 278 :33 6 13 33 61 6 Tatematsu KI, Yamazaki T, Ishika wa F (2000) MBD2-MBD3 ... Mammalian DNA MTase s 21 0 3 .1 Specificit y of Dnmt1 for Hemimeth y latedDNA 210 3 .2 CG and Non-CG Meth y lation b y Dnmt3AandDnmt3B 211 3 .3 Flankin g SequencePreferenceofMammali...
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DNA Methylation: Basic Mechanisms - Part 8 pdf
... O b stet Gyneco l 149 :38 2 38 3 P ate k E, Jo h nson P (1978) Recurrent h y d ati d i f orm mo l e. Report o f a case wit hfi ve recurrences. Acta Obstet G y necol Scand 57 :38 1 38 3 S ensi A, Gua l an d i ... Wilms’ tumor. Nat G enet 7: 433 – 43 9 T amaru H,Se lk er EU (2001) A h istone H3 met h y l trans f erase contro l sDNAmet h y l ation i n Neurospora crassa. Nature 414:277–28 3 T...
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DNA Methylation: Basic Mechanisms - Part 9 pps
... ulcerative colitis: a cancer- p rone chronic inflamma- tor y disease. Cancer Res 60 :33 33 33 3 7 Jackson AL, Loeb LA (2001) The contribution of endo g enous sources of DNA dama ge to t h emu l tip l e ... of E. coli K-12 is a stran d -an d sequence-speci fi c DNA mismatc h en d onuc l ease. Natur e 3 53: 77 6 –778 Hernan d ez-Boussar d TM, Hainaut P (1998) A speci fi c spectrum o f p 53...
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DNA Methylation: Basic Mechanisms - Part 10 pot
... 9 6 imprinte d genes – C DNK1 C 235 – H 1 9 233 , 234 , 23 6 – K CNQ1O T 1 233 – L I T1 233 – P E G 1 233 , 23 6 – P E G 3 233 , 23 4 – S NRP N 2 33 –2 36 imprintin g 229– 231 , 236 , 237 intracisternal A-t y pe particle ... review) . Sub j ect Inde x 31 9 heterochromatin 22 , 26 , 30 , 34 , 35 , 7 2 , 73 , 81 , 84 , 85 , 2 13 hi g her plants 99, 100, 1 03, 1...
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