BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 6 potx
BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 6 potx
... increased androgen and oestradiol synthes is by these cells. IGF-1 also promotes increased expression of FSH and LH receptors in ovarian tissue. 284 BIOPHARMACEUTICALS IGF biochemistry IGF-1 and -2 ... family. They include NGF, as well as brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin 4/5 (NT-4/5) and neurotrophin -6 (NT -6 ) . All are small, bas...
Ngày tải lên: 13/08/2014, 07:20
BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 1 potx
... therapeutic 8 BIOPHARMACEUTICALS Interleukin-1 (IL-1) 232 The biological activities of IL-1 233 IL-1 biotechnology 234 Interleukin-3: biochemistry and biotechnology 235 Interleukin-4 2 36 Interleukin -6 238 Interleukin-11 ... 2 36 Interleukin -6 238 Interleukin-11 240 Interleukin-5 241 Interleukin-12 244 Tumour necrosis factors (TNFs) 2 46 TNF biochemistry 2 46 Biological ac...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 2 potx
... broad-spectrum antibiotic to be discovered, and was found effective against Gram- negative and Gram-positive bacteria, rickettsias and chlamydias. It retains activity when administered orally and ... Chemistry, manufacturing and control section 4 Sampling, methods of validation, package and labelling 5 Non-clinical pharmacology and toxicology data 6 Human pharmacokinetics and...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 3 potx
... Sciences, Ireland The media constituents, several of which are heat-labile, are generally dissolved in WFI and filter-sterilized into the pre-sterile animal cell reactor. Reactor design (and operation) ... Follicle-stimulating hormone (FSH) CHO Insulin E. coli Interferon-b CHO Erythropoietin CHO Interferon-a E. coli Glucocerebrosidase CHO Interferon-g E. coli Factor VIIa BHK Interleukin-2 (...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 9 potx
... consists of single-stranded RNA (ssRNA) of approximately 5–8 kb. Upon entry into sensitive cells, the viral RNA is reverse-transcribed and eventually yields double-stranded DNA. This subse- quently integrates ... pertussis Lipopolysaccharide Oil-based emulsions Freund’s complete/incomplete adjuvants (FCA/FIA) Starch oil Saponins Quil A Liposomes Immunostimulatory complexes (ISCOMs) Some cyt...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 4 pps
... Protein Molecular mass (kDa) IFN-a 20–27 TNF-a 52* EGF 6 IFN-b 20 GM-CSF 22 NGF 26 IFN-g 20–25 G-CSF 21 Insulin 5.7 IL-2 15–20 EPO 36 hGH 22 IL-1 17.5 TPO 60 FSH 34 IL-12 30–35 IGF-1 7 .6 LH 28.5 *Biologically ... (e.g. receptors for IL-8, IL-9 and IL-10). Many contain two polypeptide components (including IL-3, IL-4 and IL-5 receptors), while a few contain three or mo re polypeptid...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 5 doc
... factors (CSFs) and platelet-derived growth factor (PDGF) Cell type Interleukins produced Macrophages IL-1, IL -6 , IL-10, IL-12 Eosinophils IL-3, IL-5 Vascular endothelial cells IL-1, IL -6 , IL-8 Fibroblasts ... cytokines (including IL-2, -4 , -5 , -6 , -7 , -1 1, -1 5 and CSFs) also play important co- stimulatory roles in the maturation of the range of blood cells. Its...
Ngày tải lên: 13/08/2014, 07:20
BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 7 ppt
... levels of PMSG and secrete it into the blood, where it is detectable between days 40 and 130 of gestation. 3 36 BIOPHARMACEUTICALS Box 8 .6. The androgens and oestrogens The androgens and oestrogens ... Ogihara, T. (19 96) . Genetics of insulin-dependent diabetes mellitus. Endocr. J. 43 (6) , 60 5 61 3. Johnson, I. (1983). Human insulin from recombinant DNA technology. Science 219...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 8 ppsx
... practice. Appl. Microbiol. Biotechnol. 57(5 6) , 60 6 61 3. Tencate, H. et al. (19 96) . Developments in anti-thrombolic therapy—state of the art, anno 19 96. Pharmacy World Sci. 18 (6) , 195–203. Walker, C & Royston, ... fibrin strands, thus dissolving the clot. tPA and plasminogen both bind to the surface of fibrin strands (b), thus ensuring rapid and efficient activation of the throm...
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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 10 ppsx
... factors 257–8 IL-1 232–5 IL-1a 232–3 IL-1Ra 234 IL-1b 232–3 IL-2 224, 225–32 IL-3 235 6, 257–8 IL-4 224, 2 36 8 IL-5 241–3 IL -6 238–40 IL-10 224 IL-11 240–1 IL-12 244 6 IL-13 224 IL-18 224 International ... effects 203–7 biotechnology 207–10 IFN-a 122, 1 96, 197–8, 210–13, 520 6 IFN-b 122, 1 96, 197, 198, 213–14 IFN-g 1 96, 197, 198, 214– 16, 278 IFN-g 1B 2 16 IFN-o 219 IFN-t 219 JAK–ST...
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