BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 3 potx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 3 potx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 3 potx

... Sciences, Ireland The media constituents, several of which are heat-labile, are generally dissolved in WFI and filter-sterilized into the pre-sterile animal cell reactor. Reactor design (and operation) ... Follicle-stimulating hormone (FSH) CHO Insulin E. coli Interferon-b CHO Erythropoietin CHO Interferon-a E. coli Glucocerebrosidase CHO Interferon-g E. coli Factor VIIa BHK Interleukin-2 (...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 1 potx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 1 potx

... therapeutic 8 BIOPHARMACEUTICALS Interleukin-1 (IL-1) 232 The biological activities of IL-1 233 IL-1 biotechnology 234 Interleukin -3 : biochemistry and biotechnology 235 Interleukin-4 236 Interleukin-6 238 Interleukin-11 ... Blood products and therapeutic enzymes 35 1 Disease transmission 35 1 Whole blood 35 3 Platelets and red blood cells 35 3 Blood substitutes 35 3...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 2 potx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 2 potx

... 57(5–6), 5 93 605. Walsh, C. (2002). Combinatorial biosynthesis of antibiotics, challenges and opportunities. Chembiochem. 3( 2 3) , 125– 134 . PHARMACEUTICALS, BIOLOGICS AND BIOPHARMACEUTICALS 41 Peptide and ... Pharm. 54(12), 1420–1 433 . Marston, A. et al. (19 93) . Search for antifungal, molluscicidal and larvicidal compounds from African medicinal plants. J. Ethnopharmacol. 3...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 6 potx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 6 potx

... 4 13 430 . Claesson-Welsh, L. (1994). Platelet-derived growth factor receptor signals. J. Biol. Chem. 269(51), 32 0 23 32 026. Downward, J. et al. (1984). Close similarity of EGF receptor and V-erb-B ... family. They include NGF, as well as brain-derived neurotrophic factor (BDNF), neurotrophin -3 (NT -3 ) , neurotrophin 4/5 (NT-4/5) and neurotrophin-6 (NT-6). All are small, basic prot...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 9 potx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 9 potx

... in the twenty-first century. Hybridoma Hybridom. 21(2), 135 –145. Poland, G. et al. (2002). Science, medicine and the future — new vaccine development. Br. Med. J. 32 4( 734 9), 131 5– 131 9. Russo, S. ... consists of single-stranded RNA (ssRNA) of approximately 5–8 kb. Upon entry into sensitive cells, the viral RNA is reverse-transcribed and eventually yields double-stranded DNA. This su...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 4 pps

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 4 pps

... Protein Molecular mass (kDa) IFN-a 20–27 TNF-a 52* EGF 6 IFN-b 20 GM-CSF 22 NGF 26 IFN-g 20–25 G-CSF 21 Insulin 5.7 IL-2 15–20 EPO 36 hGH 22 IL-1 17.5 TPO 60 FSH 34 IL-12 30 35 IGF-1 7.6 LH 28.5 *Biologically ... (e.g. receptors for IL-8, IL-9 and IL-10). Many contain two polypeptide components (including IL -3 , IL-4 and IL-5 receptors), while a few contain three or mo re polypeptide...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 5 doc

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 5 doc

... factors (CSFs) and platelet-derived growth factor (PDGF) Cell type Interleukins produced Macrophages IL-1, IL-6, IL-10, IL-12 Eosinophils IL -3 , IL-5 Vascular endothelial cells IL-1, IL-6, IL-8 Fibroblasts ... cytokines (including IL-2, -4 , -5 , -6 , -7 , -1 1, -1 5 and CSFs) also play important co- stimulatory roles in the maturation of the range of blood cells. Its g...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 7 ppt

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 7 ppt

... Nature 37 1, 35 1 35 4. Docherty, K. (1997). Gene therapy for diabetes mellitus. Clin. Sci. 92(4), 32 1 33 0. Drucker, D. (2002). Biological actions and therapeutic potential of the glucagon-like peptides. ... between days 40 and 130 of gestation. 33 6 BIOPHARMACEUTICALS Box 8.6. The androgens and oestrogens The androgens and oestrogens represent the major male and female sex...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 8 ppsx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 8 ppsx

... Opin. Pediat. 14(1) 23 33 . Goodey, A. (19 93) . The production of heterologous plasma proteins. Trends Biotechnol. 11, 430 – 433 . Kingdon, H & Lundblad, R. (2002). An adventure in biotechnology: the ... Haematol. 111(2), 38 7 39 6. Wright, G. et al. (1991). High level expression of active human a-1-antitrypsin in the milk of transgenic sheep. Bio/ Technology 9, 830 – 834 . Anticoagula...

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BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 10 ppsx

BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 10 ppsx

... 257–8 IL-1 232 –5 IL-1a 232 3 IL-1Ra 234 IL-1b 232 3 IL-2 224, 225 32 IL -3 235 –6, 257–8 IL-4 224, 236 –8 IL-5 241 3 IL-6 238 –40 IL-10 224 IL-11 240–1 IL-12 244–6 IL- 13 224 IL-18 224 International ... 31 8 insulin-dependent diabetes mellitus 30 4, 30 5 insulin glargine 31 5, 31 8 insulin-like growth factors (IGF-1 and IGF-2) 278, 279–85, 298, 32 5, 32 7, 33 1 Insulin Lispr...

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