Báo cáo y học: " Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase" doc

... HXB2-43E (5' ACA GAG ATG GAA GAG GAA GGG AAA A- 3', nucle- otides 2664–2688), 43E-RT (5' ACA GAG CTG GAA GAG GAA GGG AAA A- 3', nucleotides 2664–2688) and 43E- RTA (5' ACA TTT ... and thus cannot apparently directly influence ATP binding [41]. Rather M41L may have a more indirect effect on ATP binding perhaps via alteration of van der Waals contacts with F11...

Ngày tải lên: 13/08/2014, 06:20

... CTTTGGTCGACTTATTCCCCCGGATAATAGAT 1411-1575 165 F2-3 TGCAG GGATCCATGAATGACGACCAGTTAGAT GTCGACTTAAGCTAATGGTCCAGTAGA 1531-1731 201 F4 TGCAG GGATCCATGAATGACGACCAGTTAGAT CTTTGGTCGACTTATTCCCCCGGATAATAGAT ... TGCAG GGATCCATGATCTATTATCCGGGGGAA CTTTGGTCGACTTATTCCCCCGGATAATAGAT 1558-1575 18 F13 GATCCATGATCTATTATCCGGGGTAAG TCGACTTACCCCGGATAATAGATCATG 1558-1572 15 F14 GATCCATGTATTATCCGGGGGAATAAG TCGACTTA...

Ngày tải lên: 12/08/2014, 01:21

... and another PCR analysis was performed using the same primers as in the initial analysis. DNA of organs and tissue supernatants was extracted using the QiAamp tissue kit according to the manufacturer's ... Long-dis- tance (LD) PCR using the TaKaRa-Ex PCR system (Takara Bio inc., Otsu, Japan) according to the manufacturer's instructions. An amplification product of approxim...

Ngày tải lên: 12/08/2014, 04:21

... typically activated by inflam- matory cytokines such as TNFα and IL-1, thus playing roles in inflammation as well as in apoptosis. In compar- ison, the non-canonical NF-κB pathway is activated by lymphotoxin ... Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi- Dori, Niigata 951-8510, Japan and 3 Department...

Ngày tải lên: 12/08/2014, 23:22

... Hashimoto T, Nakamura Y, Nakamura F, Shirakura T, Adachi J, Goto N, Okamoto K, Hasegawa M: Protein phylogeny gives a robust estimation for early divergences of eukaryotes: phylogenetic place of a mitochondria-lacking ... only protein in nature known to contain the unusual amino acid, hypusi ne [N ε -(4-amino-2-hydroxybutyl) lysine], derived from a modification of lysine by sper...

Ngày tải lên: 12/08/2014, 01:21

... [2-8] and participate in maintaining joint inflammation, degradation of extracellular matrix (ECM) com- ponents, and invasion of cartilage and bone [2,4] as well as fibrosis of the affected joints ... of telomerase subunits in malignant glioma [18] as well as protein tyrosine kinases and phosphatases in human basophils in asthma and inflammatory allergy [19]. The lat...

Ngày tải lên: 09/08/2014, 10:23

... project. A wing disc cDNA library derived from fifth instar B. mori C108 larvae was kindly provided by Dr Kawasaki (University of Utsunomiya, Japan). A total of 1000 clones were s elected at random and ... UDP- glycosyltransferase. The UDP-glycosyltransferases ( UGTs) are a superfamily of enzymes that p lay a central role in the detoxication and elimination of a wide ra...

Ngày tải lên: 22/02/2014, 04:20

... present in at least two affected family mem- bers. One of these developed breast cancer and died at a very young age, and in fact one half-sister of the proband also died of lung cancer at a very young ... Mexican origin. The index case was a 23-year-old female diagnosed with breast carci- noma of the left breast with combined histological fea- tures of lobular carcino...

Ngày tải lên: 09/08/2014, 04:21

... SLE. Figure 2 Assay performance characteristics of the anti-SmD3 peptide (SMP) assayAssay performance characteristics of the anti-SmD3 peptide (SMP) assay. (a) Intra-assay and interassay variability, (b) ... (b) linearity, and (c) receiver operating characteristic analysis. The intra-assay and inte- rassay variability, expressed as coefficient of variation in percentage (CV%)...

Ngày tải lên: 09/08/2014, 06:22

... necrosis factor receptor-associated factor 6 5'-AGA CAA GAC CAT CAA ATC CGG GAG 3'-TCC AGG GCT ATG AAT CAC AAC AGG c-Fos 5'-CAG GAG ACA GAC CAA CTA GA 3'-TTC ACG GAC AGA TAA GGT ... GGA ATC CTG AAA CTC AGA 3'-TCC CGT TGC AGA CGT AGA AAC TGA Integrin αv 5'-TCC CAT CAG TGG TTT GGA GCA TCT 3'-TCC GAC AGC CAC AGA ATA ACC CAA Integrin β3 5'-TGC CTC AAC AAT ....

Ngày tải lên: 09/08/2014, 08:22