Báo cáo y học: "RNA interference: a multifaceted innate antiviral defense Ajit Kumar" ppsx
Báo cáo y học: "RNA interference: a multifaceted innate antiviral defense Ajit Kumar" ppsx
... BioMed Central
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Retrovirology
Open Access
Commentary
RNA interference: a multifaceted innate antiviral defense
Ajit Kumar
Address: Department of ... Importantly, Wu et al., [35] argue that a given
miRNA hairpin may generate more than one product.
Therefore, the designation of a particular sequence for a
given miRNA may not...
Báo cáo y học: "RNA interference: more than a research tool in the vertebrates'''' adaptive immunity" ppsx
... complexity and the dynamic interplay of cellular regulation. As plants and
invertebrates lack the protein-based adaptive immunity that are found in jawed vertebrates, the
ability of RNA silencing ... Medical Research and Public Health, Melbourne, Australia and
2
Department of
Biochemistry and Molecular Biology, Monash University, Clayton, Australia
Email: Johnson Mak* - mak@burnet.edu.au
*...
Báo cáo y học: "RNA interference has a role in regulating Drosophila telomeres" potx
... telomerase
TTAGGG
TT[T /A] GGG
TTAGG
Human
Tomato
Silk moth
HeT -A
TA RT
Ta hre
(A)
n
gag
3’ UTR
Approximately 6 kb
Approximately 12 kb
Approximately 10 kb
(A)
n
gag
pol
3’ UTR
5’ UTR
5’ UTR
(A)
n
gag
pol
3’ UTR5’ UTR
(b)
(a)
evidence ... study was HeT -A, a transposable element dedicated to
telomere maintenance in Drosophila, not a parasitic
invader. Savitsky and colleagues [2]...
Báo cáo y học: "RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells" pps
... siRNA (ASsiRNA) and negative control
(NCsiRNA) were 5’ GCUAUGACGUCAUUGCCU Att 3’
(sense), 5’ UAGGCAAUGACGUCAUAGCtt 3’ (anti-
sense) and 5’ GUUUGACUCUCCAAACGGUtt 3’
(sense), 5’ ACCGUUUGGAGAGUCAAACtt ... Medicine,
National Taiwan University, Taipei, Taiwan.
3
Department of Pharmacy,
National Taiwan University Hospital, Taipei, Taiwan.
4
National Center of
Excellence for Clinical Trial and Resea...
Báo cáo y học: "RNA interference against polo-like kinase-1 in advanced non-small cell lung cancers" doc
... 61:850-862.
14. Ochiya T, Takahama Y, Nagahara S, Sumita Y, Hisada A, Itoh H, Nagai Y,
Terada M: New delivery system for plasmid DNA in vivo using
atelocollagen as a carrier material: the Minipellet. Nat Med
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5:707-710.
15.
Song ... liver
metastases of lung cancer. Mol Cancer Ther 2008, 7:2904-2912.
52. Nogawa M, Yuasa T, Kimura S, Tanaka M, Kuroda J, Sato K, Yokota A,
Segawa H,...
Báo cáo y học: "RNA interference for CFTR attenuates lung fluid absorption at birth in rats" doc
... 5'-
GATCCGTTACACTATTAACAACAAATTCAAGAGATTT-
GTTGTTAATAGTGTAATTT TTTGGAAA-3', pSi-4, reverse:
5-AGCTTTTCCAAAAAATTACACTAT-
TAACAACAAATCTCTTGAATTTGTTGTTAATAG
TGTAACG-3'. We also used the same negative control,
pSi-0.
Respiratory ... 5'-
GCTTTTCCAAAAAATGGAGAGATGAAGAAATAT-
TCTCTTGAAATATTTCTTCATCTCTCCACG-3'; pSi-C
2
,
forward 5'-
ATCCGAAAGTATATGTACCAAGATTCAAGAGATCTTGG-...
Báo cáo y học: "RNA interference pinpoints regulators of cell size and the cell cycle" doc
... scale. For
example, the data generated can be analyzed and presented
in various ways to highlight the different phenotypic effects
(see the supplementary data accompanying [9]).
The Taipale lab ... the data manually, Bjorklund et al. [9] found that
dsRNA-mediated RNAi against eight other components of
the insulin/Tor pathway gave weak but detectable pheno-
types. Surprisingly though, they ......
Báo cáo y học: "RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals" docx
... 2003, 21:379-386.
4. Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura
M, Nishida H, Yap CC, Suzuki M, Kawai J, et al.: Antisense tran-
scription in the mammalian transcriptome. Science ... 2005,
309:1564-1566.
5. Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N,
Oyama R, Ravasi T, Lenhard B, Wells C, et al.: The transcriptional
landscape of the mammalian genome....
Báo cáo y học: "Intramuscular Olanzapine – a UK case series of early cases" ppsx
... injections
of olanzapine, lorazepam or placebo in treating acutely agi-
tated patients diagnosed with bipolar mania. J Clin Psychophar-
macology 2001, 21:389-397.
9. Kay SR, Sevy S: Pyramidical model ... bushe_chris@lilly.com; Mark Taylor - Mark.Taylor@glacomen.scot.nhs.uk;
Mathew Mathew - mathew@vmmathew.fsnet.co.uk
* Corresponding author
Abstract
Background: Clinical trials assessing effi...
Báo cáo y học: "Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice" ppsx
... commercially
available ELISA kits (R&D Systems, Minneapolis, MN,
USA) according to m anufacturer’sprotocol.Thesame
cytokines were also measured in plasma.
Presentation of data and statistical analysis
All ... FG, Szabo C,
Salzman AL: Flagellin, a novel mediator of Salmonella-induced epithelial
activation and systemic inflammation: I kappa B alpha degradation,
induction of nitric oxide s...