Báo cáo y học: " The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion" potx
Báo cáo y học: " The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion" potx
... that this glycan protects the CD4BS against antibodies. Conclusion: The carbohydrate at position 386 is not essential for protein folding and function, but is involved in the protection of the CD4BS ... purposes) Retrovirology Open Access Research The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein fold...
Ngày tải lên: 13/08/2014, 06:20
Báo cáo y học: "The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro" pdf
... antagonist WIN62577 inhibited ASMC IL-13-induced proliferation and ASMC migration in vitro and therefore may be a new therapeutic option in asthma. Introduction Asthma is a chronic inflammatory disease ... activate the neurokinin (NK)-1 and NK-2 receptors, leading to potent effects on a irway smooth muscle tone and secretions, bronchial circulation, and inflammatory and...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro" potx
... antagonist WIN62577 inhibited ASMC IL-13-induced proliferation and ASMC migration in vitro and therefore may be a new therapeutic option in asthma. Introduction Asthma is a chronic inflammatory disease ... In this experiment, we demonstrated tha t NK-1R antagonist WIN62577 had the effect of inhi- biting ASMC migration in vitro, indicating that WIN62577 may contribute to the...
Ngày tải lên: 11/08/2014, 06:23
Tài liệu Báo cáo Y học: The effects of low pH on the properties of protochlorophyllide oxidoreductase and the organization of prolamellar bodies of maize (Zea mays) pot
... presented in Fig. 12B, is very similar to that for the photoconverted enzyme, indicating that it is the conform- ational changes that predominate in both cases. Minor differences were seen in the rates ... shift in the absorption maximum of the photoconverted enzyme occurring under these conditions to be inhibited by ATP and by the protein phosphatase inhibitor N...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: The porcine trophoblastic interferon-c, secreted by a polarized epithelium, has specific structural and biochemical properties potx
... potential glyco- sylation sites present on the IFN-c polypeptide core. They could differ in the rate and site of glycosylation, considering the 22 500-Da band as bi-glycosylated and the 18 000-Da band ... latter isoform being glycosylated on N16. As expected, the correspondance between the measured masses and observed M r in SDS/PAGE is quite good for nonglycosyl...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: "The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanase" docx
... gain new insight into the effect of the drug on the regulation of 5-LOX, one of the main enzymes involved in the synthesis of LTB 4 by chondrocytes [4,24]. Figure 2 Cathepsin K gene expression ... local action on chondrocytes and the synthesis of catabolic factors and, second, by being an important upregulating factor in the synthesis of IL-1β by OA synovium. This...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "The association between patellar alignment on magnetic resonance imaging and radiographic manifestations of knee osteoarthritis" ppsx
... Arthri- tis Foundation, and by an Arthritis Foundation Clinical Sciences Grant. The study sponsor was not involved in study design, in the collection, analysis, and interpretation of data, in the ... design and coordination of the study, read the MRIs, and prepared the manuscript. YZ participated in the design of the study. JN performed the statistical a...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseases" ppsx
... permitted in START as long as they did not have conditions or concomitant medications that were prohibited by the product labeling. Data from the Ankylosing Spondylitis Study for the Evaluation of ... REMICADE Therapy (START) (n = 1083), the Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy (ASSERT) (n = 279), and the Infliximab Multinatio...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "The effects of infliximab therapy on the serum proteome of rheumatoid arthritis patients" pptx
... analysis showing canonical pathways of the 39 differentially expressed proteins after infliximab treatment in the responder group. The pathways are indicated on the y- axis. The x-axis indicates ... respondersIngenuity pathway analysis of proteins displaying alterations in expression patterns following infliximab treatment in patients deemed to be respond- ers. (See Results...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "The effect of CpG-ODN on antigen presenting cells of the foal" ppt
... the observations with the top line indi- cating the upper quartile, the middle line showing the median value, and the lower line indicating the lower quartile. The lines extending from the box ... tissues. Therefore, the combination of cell surface marker expres- sion, using the monoclonal antibodies available for the horse species, and the expression of cytoki...
Ngày tải lên: 11/08/2014, 10:23