Báo cáo y học: " Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses" ppt

... Central Page 1 of 11 (page number not for citation purposes) Retrovirology Open Access Research Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic ... containing syncytia in response to focal areas of virus infected cells. Plates were fixed and stained 3 days later and examined for plaques of s...

Ngày tải lên: 13/08/2014, 06:20

... severity of arthri- tis was scored by grading each paw from 0 to 4 based on erythema, swelling and deformity of the joints, resulting in a maximum score of 16. MHC class II–peptide binding assay Lewis ... start of each experiment. This study was approved by the Dutch Committee of Animal Experiments. Induction and clinical evaluation of AA AA was induced by intradermal inje...

Ngày tải lên: 09/08/2014, 03:24

... of cases by the presence of antinuclear antibodies [1]. SSc may affect virtually any organ of the body, includ- ing skin, gastrointestinal tract, lungs, heart, kidneys, and musculoskeletal system. ... Our findings demonstrate the occurrence of selective alterations in A 2B AR density and signalling in SSc. Keywords: adenosine, A 2 adenosine receptors, neutrophils, receptor...

Ngày tải lên: 09/08/2014, 06:22

... examine the characteristics of VDR gene BsmI polymorphisms in patients with SLE and the relationship of polymorphisms to the susceptibility and clinical manifestations of SLE, VDR genotypings of ... between VDR polymorphism and many non-skeletal diseases [20]. Although SLE has features consistent with Th2-type cytokine predominance, both Th1 and Th2 cytokine may be involve...

Ngày tải lên: 09/08/2014, 07:20

... physiological association between osteocal- cin and bone formation. The findings suggest a defect in bone formation that may be explained, in part, by systemic inflamma- tion. Indeed, in one of ... were included in several analysis of covariance models for bone mineral density (BMD) variations (final values minus initial values) to analyze the effect of cofactors (continuous...

Ngày tải lên: 09/08/2014, 10:20

... pulmonary infections are still a dan- gerous consequence of the secondary humoral immune deficiency in CLL, the frequency and severity of the infec- tions in our patient were certainly due to a combined humoral ... detectable hemolysis. In addition, protracted thrombocytopenia Immunophenotype of chronic lymphocytic leukemia of the B-cell-lineage at primary diagnosis in 2002:...

Ngày tải lên: 11/08/2014, 21:22

... have no competing inter- ests. Authors' contributions EP is the senior author and was involved in collecting patient details, reviewing the literature and final proof- reading of the manuscript. ... Turin, Italy and 2 Nuclear Medicine Unit, University of Turin, Corso Bramante, 10126 Turin, Italy Email: Ettore Pelosi* - e.pelosi@irmet.com; Andrea Skanjeti - askanjeti@yahoo.i...

Ngày tải lên: 11/08/2014, 23:21

... pathophysiology. CRA chal- lenge similarly resulted in induction of lung cytokines and chemokines. These included the T H 2 cytokines IL-4 (P < 0.05) and IL-5 (P < 0.05), whose actions include, ... RM, Warmington K, Lincoln P, Chensue SW, Kunkel SL: Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chem- okines in...

Ngày tải lên: 12/08/2014, 15:21

... purposes) acute inflammatory reaction involving numerous neutrophils. Inflammatory infiltrates were observed within the proliferating and thickened synovial lining layer with profound lymphocytic and granulocyte ... disease Skin, joints, keratinocytes Knockout, conditional knockout and gain of function (transgenic) approaches applied to study the role of Jun and Fos proteins dur...

Ngày tải lên: 09/08/2014, 10:22

... c-Jun-N-terminal kinase induced by IL-1β [17].  is resulted in the reduced accumulation of phosphorylated c-Jun and activation protein-1 DNA binding activity, and of activation protein-1-mediated in ... by the activation of synovial tissue lining the joint capsule, which results in the invasion of the cartilage and bone leading to the progressive joint dysfunction [1...

Ngày tải lên: 12/08/2014, 12:20