Báo cáo y học: " microRNAs in viral oncogenesis" ppt
Báo cáo y học: "MicroRNAs in systemic rheumatic diseases" pdf
... DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol 2010, 184:6773-6781. 51. Zhao S, Wang Y, Liang Y, Zhao M, Long H, Ding S, Yin ... miR-124a binding in the 3’ UTR of cyclin- dependent kinase 2 (CDK2) and monocyte chemo- attractant protein 1 (MCP-1) mRNA. In fact, induction of miR-124a in RA synoviocytes signifi cantly...
Ngày tải lên: 12/08/2014, 17:21
Báo cáo y học: "Osteoimmunology in rheumatic diseases" pptx
... [23]. This link between proinflammatory cytokines and osteoclast formation most likely explains why cytokine-targeted therapy, particularly blockade of TNF, is highly effective in retarding structural damage ... lineage types such as Kupffer cells in the liver or microglia in the brain. It is not fully clear whether some monocytes entering an inflamed joint are already committed to the...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Vasculogenesis in rheumatoid arthritis" pptx
... origin as Lin − /7-aminoactinomycin D (7AAD) − / CD34 + /CD133 + /VEGFR-2 + cells and the number of these cells was indeed higher in RA patients compared with controls. In addition, the colony-forming ... late-outgrowth EPCs of solely heman gioblastic origin may be involved in vascular repair. As this EPC subset may be preferentially involved in the active stage of the disease, i...
Ngày tải lên: 12/08/2014, 11:23
Báo cáo y học: " Claudins in lung diseases" ppt
... cellular integrity, and create hydrostatic pressure differentials maintaining integrity of cystic compartments [31,32]. Additionally, claudin 1 may have a role in right-left patterning of the embryonic ... causing infections are many some of which may act by downregulating claudins or causing their deranged distribution inducing changes in tight junc- tional permeability allowing pathogen...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " Influenza A viral loads in respiratory samples collected from patients infected with pandemic H1N1, seasonal H1N1 and H3N2 viruses" pdf
... Y: In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature 2009, 460:1021-1025. 14. Ison MG: Influenza in hospitalized adults: gaining insight into a significant ... for quantifying viral RNA copy numbers of the contemporary subtype and strain present in the test specimens, with the assumption that the full length in vitro M RNA transcripts clos...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: " Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death" pot
... assays. SL participated in B-LCL phenotyping and staging assay. TS participated in B-LCL phenotyping, staging, and fusion assay. TC participated in staging and fusion assay. AH participated in in ... define the mechanisms underlying the variable intrinsic susceptibility of rhesus monkey PBMC to SIVsmE660 infection. In a cohort of 15 unrelated Indian-origin rhesus monkeys, infectabi...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: "Advances in immunomodulating therapy of HBV infection"
... lamivudine and adefovir dipivoxil. The immunomodulators act by promoting cytotoxic T cell activity for lysis of infected hepatocytes and by stimulating cytokine production for control of viral ... respectively. Interestingly, an increase in virological response over time after the discontinuation of thymosin could be observed (p=0.02) [40]. The doses of thymosin α-1 in this meta-anal...
Ngày tải lên: 02/11/2012, 11:17
Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... intermediate intermediate No intermediate intermediate intermediate yes DNA arrays na intermediate intermediate no high high low yes Indirect methods Viral load na na na yes intermediate low low yes ... generally defined clinically by a rise in serum HBV DNA levels during antiviral therapy. Although HBV DNA assays will eventually detect changes in viral load as a consequence of...
Ngày tải lên: 03/11/2012, 09:41
Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... its (already low) residual electron transfer activity is not maintained by the neighbouring tyrosine, while the W121F /Y1 22F mutant activity may be viewed as a commitment of the tyrosine residue ... potential entry site: mutations in an exposed tyrosine (Y2 26F; see Table 1) and in a histidine (H119N; Table 2) show wild-type kinetics. Biphasic steady-state kinetics Non-linear kinetics ha...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... obtained by analytical ultracentrifugation using the direct binding assay as des- cribed in Experimental procedures. Inset: Linearized plot of the binding data for apoE(263–286) (symbols) shown in ... possessing a similar apparent binding affinity (K d ) for the large lipid particles, are notably distinct in their maximum binding capacities (Table 2). In particular, the binding footpri...
Ngày tải lên: 08/03/2014, 09:20