Báo cáo y học: "Characterization of the invariable residue 51 mutations of human immunodeficiency virus type 1 capsid protein on in vitro CA assembly and infectivity" docx
Báo cáo y học: "Characterization of the invariable residue 51 mutations of human immunodeficiency virus type 1 capsid protein on in vitro CA assembly and infectivity" docx
... produc-Turbidity assay showing the effects of CAp24 mutations on in vitro CA assemblyFigure 4Turbidity assay showing the effects of CAp24 muta-tions on in vitro CA assembly. Turbidity assay showing the increase ... purposes)RetrovirologyOpen AccessResearchCharacterization of the invariable residue 51 mutations of human immunodeficiency virus type 1 capsid protein on in vitro CA assembly and infectivitySamir Abdurahman 1 , ... formation in vitro, virus replication and virus capsid formation.Results: We extended the above investigation by introducing three different D 51 substitution mutations (D51N, D51E, and D51Q) into...
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Báo cáo y học: "A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α" potx
... shown.NL-vifS 10 000 10 00 10 0 1 100 .1 0. 01 02648Days after infectionp24 ng/mLNL-G 116 EvifS 10 000 10 00 10 0 1 100 .1 0. 01 02648Days after infectionp24 ng/mLNL-4/5SG 116 E6/7S vifS 10 000 10 00 10 0 1 100 .1 0. 01 02648Days ... nucleotide substitution at the 347th position of the CA region, resulting in a G-to-Esubstitution at the 11 6th position of the CA (G 116 E).Analysis of 95 HIV -1 strains in the Los Alamos HIVsequence ... replicative capability in human cellsTo determine whether the single amino acid substitutionat the 11 6th position of the CA improved the replicativecapability of NL-4/5S6/7SvifS in human...
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Báo cáo y học: "Phenotypic and genotypic characterization of Human Immunodeficiency Virus type 1 CRF07_BC strains circulating in the Xinjiang Province of China" pot
... CRF07_BC and subtype B' viruses The number and location of the potential N-linked glyco-sylation sites in the V1–V5 regions in gp120 of the CRF07_ BC and subtype B' viruses were analyzed. ... in the cor-responding regions in China.Comparison of the replication kinetics of the CRF07_BC R5 virus with that of the subtype B' R5 and R5/X4 virusesFigure 7Comparison of the replication ... CRF07_BC and subtype B' viruses(Fig. 3 and 4). There was also a significant difference in the frequency of N-glycosylation sites, including N130, N133,N136, N144, and N186 in the V1/V2 region...
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Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx
... pharmaceuticalproduction. Incubation of ORF6 with N-acetylornithine and arginine to produce N-acetylarginine, followed byincubation with CAS and appropriate cofactors resulted in the formation of 3-hydroxy-N-acetylarginine, ... partial-purification and regulation of key enzymes of the acetyl cycle of arginine biosynthesis in Bacillus stearothermophilus – dual function of ornithine acetyltransferase. J. Gen. Microbiol. 13 9, 393–402.22. ... Presumably, incubation of L-N-acetylor-nithine results in reversible acetylation of the active sitethreonine 18 1 [25] and deacetylation by water cannotcompete with that byL-N-acetylornithine.Some...
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Báo cáo Y học: Hemocyanin from the keyhole limpet Megathura crenulata (KLH) carries a novel type of N-glycans with Gal(b1–6)Man-motifs doc
... overview of the complexity of KLHglycosylation, intact glycoprotein was subjected to automa-ted hydrazinolysis. Resulting glycans were pyridylaminated and analyzed by on- line ESI-MS. Both monitoring ... example, during prolonged captivity of the animals [2], may clearly in uence the molar proportions of the monosaccharide constituents of this glycoprotein.Furthermore, the ratio of KLH1 and KLH2 ... liberation of both N- and O-linkedglycans. In parallel, a total glycan fraction was preparedfrom intact KLH by hydrazinolysis using similar conditions.Pyridylamination of oligosaccharidesChemically...
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Báo cáo y học: "What is the clinical and ethical importance of incidental abnormalities found by knee MRI" docx
... inciden-tal findings. In the non-clinical research setting, any abnormal-ity, even if finally diagnosed as benign, is a matter of medical and ethical concern: the researcher has a duty of care ... identified bone and cartilaginous tumours identi-fied by clinically indicated plain radiographs for non-muscu-loskeletal indications, such as sinus radiography [13 ]. In contrast, many of our participants ... of view 16 cm; 60 partitions; 512 × 19 6 matrix; one acquisition,time 11 minutes 17 seconds; sagittal images were obtained ata partition thickness of 1. 5 mm and an in- plane resolution of 0. 31 ×...
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Báo cáo y học: "Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics" pdf
... Youngmodulus, indicating the speed of sound, the density of amaterial, and the acoustic impedance of a material [4], and presented the Gabor function as the mother wavelet and equations [2]. The signal intensity ... obtain information on the degeneration of human articularcartilage in vivo.It is not easy to calculate the intrinsic physical characteristicsfrom an ultrasonic echo obtained under arthroscopy. ... intensity did not depend on the surface curvature for radii >40 mm, and mainly reflects the condition from the surface of the cartilage to a depth of onewavelength (about 0 .15 0 mm) [5]. The tip of...
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Báo cáo y học: " Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains" pot
... stimulation is tuneddown in the presence of the viral protein [10 -14 ]. Finally,during production of progeny virus, Nef augments the intrinsic infectivity of cell-free HIV particles by a factor 5– 10 ... HIV -1 infectivity and replication without increasing microdomain association of Gag in producer cellsFigure 1 Nef boosts HIV -1 infectivity and replication without increasing microdomain association ... highly sensitive in vitro approach.Besides SM, HIV -1 virions are also highly enriched in the unusual sphingolipid dihydrosphingomyelin (DHSM) and inhibition of sphingolipid synthesis resulted in...
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Báo cáo y học: "Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum" doc
... membrane-spanningdomain of the human immunodeficiency virus type 1 Vpu protein. Virology 19 98, 2 51: 96 -10 7.54. Gottlinger HG, Dorfman T, Cohen EA, Haseltine WA: Vpu protein of human immunodeficiency virus ... immunode-ficiency virus type 1 Vpu protein induces rapid degradation of CD4. J Virol 19 92, 66: 719 3-7200. 21. Bour S, Schubert U, Strebel K: The human immunodeficiency virus type 1 Vpu protein specifically binds ... Vpu. On the basis of these novel findings, a systematic analysis of the role of cytosolic serine, threonine, cysteine and lysine residues in Vpu-mediated CD4 ubiquitination and degradation iswarranted.Our...
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Báo cáo y học: "Insight into the molecular requirements for pathogenicity of Fusarium oxysporum" pdf
... genes are involved in pathogenicity: first, the isolation of the original insertional mutant carrying a muta-tion in or close to the ORF of this gene; and second, the veri-fication of the pathogenicity ... werecomparable to the disease index of the wild -type infection and in all cases significantly different from the disease index of the corresponding pathogenicity mutant (Figure 4). In addition, the reduced ... for the infection process. Inactivation of the global nitrogen regula-tor Fnr1 abolished the expression of nutrition genes normallyinduced during the early phase of infection, and resulted in reduced...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíBT Tieng anh 6 UNIT 2Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ