Báo cáo y học: " The HIV RNA setpoint theory revisited" pps
Báo cáo y học: " The HIV RNA setpoint theory revisited" pps
... infec-
tion. For the evolution of viral load, the setpoint theory
was introduced soon after the implementation of HIV
RNA assays [1,2]. Three components describe the setpoint
behaviour after the high ... time
depend on the scale that is used to visualize trends. In reconsidering the setpoint theory for HIV
RNA, we analyzed the evolution of CD4 T-cell count and...
Báo cáo y học: "The HIV-1 Rev/RRE system is required for HIV-1 5’ UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particle" ppsx
... making the
HIV- 1 RNA more amenable to RNA- RNA and RNA-
protein interactions in the cytopla sm, which support
subsequent RNA encapsidation. Nonetheless, the com-
bined effects of the Rev/RRE system ... [20].
Furthermore, the tRNA
Lys
primers may also promote
reverse transcription at a low efficiency from the MLV
PBS (normally primed by tRNA
Pro
) in the heterologous
MLV...
Báo cáo y học: " The retrovirus RNA trafficking granule: from birth to maturity" pot
... as the metabolic
machineries for RNA in the cytoplasm are made by RNA-
binding proteins, some of which mark the RNA before
their exit from the nucleus and modulate RNA fate in the
cytoplasm. The ... of the unspliced 9 kb and
singly spliced 4 kb viral RNAs in the nucleus [93-96]. Only
the fully processed 2 kb viral mRNAs accumulate in the
cytoplasm in the absence...
Báo cáo y học: " The retroviral RNA dimer linkage: different structures may reflect different roles" potx
... is
that involved in the dimer linkage of HIV- 1. The discovery
of the sequences involved, the subsequent description of
the RNA: RNA interaction, and the elucidation of the terti-
ary interaction are ... affect the auto-complementarity of the
sequence.
One of the key differences between HIV- 1 and HIV- 2 rep-
lication is their modes of packaging [32]. Whilst the Gag...
Báo cáo Y học: The mitochondrial-lysosomal axis theory of aging Accumulation of damaged mitochondria as a result of imperfect autophagocytosis ppt
... a
variety of hydrolytic enzymes into the cytosol. Such lysosomal enzymes
may directly activate Bid, pro-caspases, or lytic cytosolic pro-enzymes
such as phospholipase A2, while the latter, together ... ferryl or
perferryl radicals) may be sufficient to jeopardize the stability
of the lysosomal membrane and to induce leak into the
cytosol of lysosomal lytic enzymes. Moderate release o...
Báo cáo y học: "The role of osteoprotegerin in arthritis" ppsx
... eccentrically starting from
the junction zone, where the bone, the cartilage and the
synovial membrane are closely attached to each other
(Fig. 2). Bone is invaded by an inflammatory synovial tissue,
known ... mg/kg/day 6.4 mg/kg/day 3 mg/kg/day
Start Onset of symptoms Onset of symptoms Onset of symptoms
Duration 7 days 35 days 5 days
Effect on inflammation No No No
Effect on cartilag...
Báo cáo y học: "The high-risk surgical patient revisited" docx
... survivor values of cardiac index. Oxygen delivery and oxygen
consumption as resuscitation endpoints in severe trauma. Trauma 1995,
38:780-787.
5. : Pulmonary Artery Catheter Consensus Conference: consensus
statement. ... randomised controlled trial of the
effect of deliberate preoperative increase of oxygen delivery on
mortality and morbidity in high-risk surgical patients. JAMA 1993,
270:2...
Báo cáo y học: "The role of collagenase in emphysema" ppsx
... emphysema. These studies
introduce the concept that cells other then inflammatory
cells may participate in the destruction of the lung in
emphysema.
Conclusion
Our scope of understanding of the ... from type I and III collagen
are widely distributed in the lung. They are present in the
adventitia of pulmonary arteries, the interstitium of the
bronchial tree, the interlobular...
Báo cáo y học: "The role of surfactant in asthma" ppsx
... components.
Lymphocytes
T lymphocyte proliferation and cytokine release is an
important step in the further activation of the adaptive
immune system in asthma. This T-cell response can
induce B lymphocyte ... synthesize lamellar bodies or DPPC.
To conclude, local synthesis of surfactant components in
the airways might indicate the possibility of adaptation and
regulation of the airw...
Báo cáo y học: "The struggle to detect circulating DNA" pps
... Unfortunately, the
authors provide no information on liver function, because
most nucleosomal DNA is efficiently cleared by the liver and
only a small fraction is eliminated by the kidney [8,9]. ... from further degradation by endonucleases [7].
In healthy individuals, the concentration of circulating DNA is
low, because dead cells are removed efficiently from
circulation by phagocyte...