Báo cáo y học: " Human immunodeficiency virus type 1 specifi

Báo cáo y học: " Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B''''/C Recombinant (CRF07_BC)" pdf

... among the most frequently targeted proteins by CTL in subjects infected with HIV -1, including clades B and C [9 ,10 ,12 ,13 ,29,30]. Such clustering pattern of CTL epitopes in HIV -1 proteins has led to ... can facilitate future HIV -1 vaccine development in China. Background HIV -1 specific cytotoxic T lymphocyte (CTL) responses play pivotal roles in driving HIV -1...

Ngày tải lên : 13/08/2014, 05:22

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Báo cáo y học: " Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles" ppsx

... 7 :11 9 http://www.virologyj.com/content/7 /1/ 119 Page 6 of 11 interface, if it has at least one atom within 5.0 Å distance to any atom. With the exception of R80 many of the selected residues are within the dimer interface. ... 2 010 , 7 :11 9 http://www.virologyj.com/content/7 /1/ 119 Page 9 of 11 ested for several years in evaluating the contribution of auxiliary proteins includ...

Ngày tải lên : 12/08/2014, 04:20

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Báo cáo y học: " Human Immunodeficiency Virus type-1 reverse transcriptase exists as post-translationally modified forms in virions and cells" pdf

... Kinetics of human immunodeficiency virus type 1 (HIV) DNA integration in acutely infected cells as determined using a novel assay for detection of integrated HIV DNA. J Virol 20 01, 75 :11 253 -11 260. 18 . ... activated during early infection, that RT is a substrate for phosphorylation and that phosphorylation may affect RT activity. We therefore investigated whether HIV RT un...

Ngày tải lên : 13/08/2014, 05:21

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Báo cáo y học: " Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains" pot

... microdomains contributes to its enhancement of virion infectivity [18 , 21, 23]. We confirm here that in the context of T lymphocyte infection, Nef does not facilitate recruitment of HIV -1 Gag into ... activity. Nef does not recruit HIV Gag into detergent resistant microdomains in infected MT-4 T lymphocytes To address potential reasons for the Nef-mediated increase in vir...

Ngày tải lên : 13/08/2014, 05:22

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Báo cáo hóa học: " Human Immunodeficiency Virus type 1 in seronegative infants born to HIV-1-infected mothers" doc

... Thus, we cannot attribute positive PCR results to contamination. To detect integrated HIV -1 DNA, 2 µg of DNA were subjected to amplification by Alu-LTR PCR [8], using the Alu primer and HIV -1 ... constructed by the neighbor-joining method and tree was bootstrapped with 10 0 replications. We used the Kimura two-parameter model to calculate sequence varia- tion within the LTR sequences....

Ngày tải lên : 20/06/2014, 01:20

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Báo cáo y học: "Human immunodeficiency virus infection and autoimmune hepatitis during highly active anti-retroviral treatment: a case report and review of the literature" potx

... highly active anti-retroviral treatment (HAART) in patients with HIV infection without evidence of co- infection with hepatitis viruses poses a diagnostic dilemma. This may be due to treatment side ... erythematosus in HIV -infected patients treated with highly active antiretroviral therapy. Int J STD AIDS 2003, 14 :356-359. 13 . Sommer S, Piyadigamage A, Goodfield MJ: Systemic l...

Ngày tải lên : 10/08/2014, 23:21

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Báo cáo y học: "Human immunodeficiency virus seroconversion presenting with acute inflammatory demyelinating polyneuropathy: a case report" pps

... therapy at higher CD4 counts and improved. Our patient's apparent treatment response was unusually rapid, raising the possibility that HAART initiation was coincidental with onset of natural ... 20% remain disabled at one year despite treatment. Outcomes in HIV-positive patients are equiva- lent to those of HIV-negative patients. Early treatment with plasmapheresis or IVIg therapy...

Ngày tải lên : 11/08/2014, 19:21

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Báo cáo y học: "Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS" pdf

... complexed with the transferred strand of proviral DNA is sterically consistent with docking of INSTIs. Both compounds interacted with the two metals within the catalytic cavity. In both cases, the metal-interacting groups ... clinical trials [1, 15 ,16 ]. The anti-HIV -1 potency of INSTIs at least equals that of NNRTIs and PIs [1, 15]. FIV IN was characterized in the last decade...

Ngày tải lên : 13/08/2014, 05:22

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Báo cáo y học: " A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames" ppt

... context of our operational defini- tion of an "immutable CTL epitope" is that SIVtat2ex is a transitional "escape" virus of SIVtat1ex; and that in certain settings SIVtat1ex virus ... virus cannot durably transit to its more fit SIVtat2ex form because the host maintains a potent CTL selection targeted against an epitope within the sec- ond coding exon of Tat. An in...

Ngày tải lên : 13/08/2014, 09:21

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Báo cáo y học: " Human herpes virus 8 replication during disseminated tuberculosis in a man with human immunodeficiency virus: a case report" pdf

... DNA in the PBMCs of all the patients under study. This value was slightly higher in patients with MCD and KS. It is also important to note that two of the 12 patients with asymptomatic HHV-8 infection ... multicentric Castleman's disease needs to be studied further to determine its sensitivity and specificity. Finally, when faced with the dilemma of urgently starting chemother...

Ngày tải lên : 11/08/2014, 17:21

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Báo cáo y học: " Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B''''''''/C Recombinant (CRF07 BC)" pdf

Báo cáo y học: " Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B''''/C Recombinant (CRF07_BC)" pdf

Báo cáo y học: " Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles" ppsx