Báo cáo y học: "Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity" pptx

... domain confers antiviral activity and Vif sensitivity to A3A and carries determinants required for the assembly into viral NPC. Results APOBEC3A has no antiviral activity and is insensitive to degradation ... assembly into viral NPCs. Interestingly, addition of the A3G N-terminal domain resulted in the targeting of the chimeric protein to viral NPCs. At the same...

Ngày tải lên: 13/08/2014, 05:22

... mind when reading a mortality survey to determine the validity of the study and the applicability of the findings to their settings. Public health scenario You are a physician working for an international ... which the true mortality rate actually lies. In practice, investigators usually use the 95% CI, the range that includes the true mortality rate 95% of the time. Th...

Ngày tải lên: 25/10/2012, 10:31

... olfactory access to the food item in addition to the auditory effect. It would be interesting to exclude other sensory inputs while evaluating the potential enhancement of eating pleasure by listening ... emotions. Psychosomatic Medicine 1992, 54(4):422-435. 7. Hetherington MM: The physiological-psychological dichotomy in the study of food intake. Proceedings of the Nutritio...

Ngày tải lên: 08/08/2014, 21:20

... properly cited. Abstract Introduction Axial spondyloarthropathy (SpA) is a group of inflammatory diseases, with ankylosing spondylitis as the prototype. SpA affects the axial skeleton, entheses, ... purposes) Introduction Axial spondyloarthropathy (SpA) is a family of polygenic inflam- matory diseases for which the pathophysiology is complex, with much remaining unknown. Ankylosing sp...

Ngày tải lên: 09/08/2014, 14:22

... possible to feel the obstructi ng foreign body within the common iliac artery. Once vascular control was obtained the artery was opened and the bullet removed (Figure 3 and 4). The embolectomy of the ... at the first surgery we were not able to say if the arterial obstruction occurred in the period between the first and second surgery or was missed the first time. In...

Ngày tải lên: 10/08/2014, 23:22

... reported that the incidence of metastases to the spleen ra nged from 0.3% to 4.8%, based on autopsy reports. The pau- city of afferent lymphatics to the splenic parenchyma and the motility of the organ ... 4 making them more likely to be confused with primary splenic tumors such as lymphomas or hamartomas [5]. The location of the primary tumor appears to affect the...

Ngày tải lên: 11/08/2014, 14:21

... Thickened Thickened Cystoscopy Mild inflammation Erythematous patches Mild squamous metaplasia, ulcerated patches Erythematous patches Erythematous patches Biopsy Negative Epithelial denudation, ... complaints, as the timing of the onset of symptoms correlated strongly with the commencement of ketamine use. In addition, the evidence shows our case to be consistent in many ways wit...

Ngày tải lên: 11/08/2014, 21:22

... high local anti-inflammatory activity. The anti-inflammatory effi- cacy of Ciclesonide in these studies was similar to that produced by Fluticasone but with an improved safety profile, thus demonstrating ... in the study of smoking-related inflam- mation. Mice were exposed to smoke for one to three days and the inflammatory response was studied. First he demonstrated the develop...

Ngày tải lên: 12/08/2014, 18:20

... dealing with a crying baby, reducing the risk of injury to the infant by a frustrated parent. How safe is manual therapy for the paediatric patient? Although manual therapy is the treatment identified ... with chiropractors, chiropractic is a profession, not a therapy. Manual therapy is provided by many other types of clini- cians including osteopaths, medical doctors, physiothera-...

Ngày tải lên: 13/08/2014, 14:20

... and the Gasteiger-Marsili formalism [20] was employed to derive the partial charges on the atoms. The AUTOTORS utility, included in the latest version of AutoDock (3.0.5) [26], was used to define ... of RITA and to improve the activity of a new family of potent anti-cancer drugs. Conclusion The aim of the present study was to support the viability of the multi-targ...

Ngày tải lên: 13/08/2014, 23:20