Báo cáo y học: "Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep" pdf

... that occur during the initiation and progression of chronic leukemia such as ATL and B-CLL in human. In the model of BLV-induced leukemia and lymphoid tumors, viral infection and tumor progression ... is linked with the onset of acute leukemia. We propose that in this particular case, the mechanism by which the immune system destroys developing...

Ngày tải lên: 13/08/2014, 05:22

... Annota- tion Tool. Then, the administrator reviews the annotation and is able to edit any attributes of the record. When satisfied with their analysis, the administrator accepts or rejects the anno- tation. ... creation and Community Utilities for regulating the acceptance of the annotations into a community gene set. The yrGATE Annotation Tool can be used withou...

Ngày tải lên: 14/08/2014, 16:21

... [5-8]. The mechanisms influencing the severity of the O3-induced pulmonary reaction and the molecules involved in the modulation of this response are yet to be fully determined. Surfactant protein-D ... importance of SP-D in the protection against the ini- tial O 3 -induced injury and during the resolution of the inflammation is confirmed in SP-D knockout...

Ngày tải lên: 12/08/2014, 16:20

... discharged from the ICU with a tracheostomy, provision of tracheostomy care by an intensivist-led multidisciplinary team may lead to improve- ments in decannulation rates and length of stay. The ... the wards by the multidisciplinary tracheostomy review team. The team consists of an intensivist, an ICU liaison nurse, a physiotherapist, a speech pathologist, and a dieti...

Ngày tải lên: 13/08/2014, 10:20

... use, distribu tion, and reproduction in any medium, provided the original work is properly cited. Endotoxin is one of the most potent known activators of innate immunity and the inflammatory response ... involved in study design and data analysis, and contributed to the manuscript. All authors reviewed and approved the final manuscript. Competing interests ADR...

Ngày tải lên: 14/08/2014, 07:21

... effect of high pro-inflammatory cytokine levels originating in adjacent active arthritis of the hand joints. On the other hand, it may also be partially explained by methodological issues. Firstly, ... in the majority, even in this early stage of the disease. Conclusions In the first year of RA, accelerated hand BMD loss is asso- ciated with progressive joint dam...

Ngày tải lên: 12/08/2014, 14:21

... findings and interpretations. APV was instrumental in the coordination of the study and the performance of data gathering. He carried out the cytokine ELISAs. He was also intimately involved with ... gathering and analysis. He read the final version of the manuscript and agrees with all reported findings and interpretations. JJH was instrumental in data gat...

Ngày tải lên: 14/08/2014, 07:21

... electro- phoresis ⁄ MS and immunohistochemistry in combina- tion, the aim of this study was to investigate the genesis- and metastasis -associated proteins, and to Keywords carcinogenesis; colorectal carcinoma; proteomics; ... role in the progression and metastasis of CRC. In summary, the techniques of proteomic analysis provide a dramatic means of screening f...

Ngày tải lên: 23/03/2014, 03:20

... predo- minantly of sinusoidal-type, containing a rich network of intratumoral microvessels supported by sinusoidal- derived myofibroblasts; while a minority were of portal- type, containing a lower ... inhibitor of promet astatic effects of hepatic inflammation created in the liver microenvironment by tumor-induced IL-18. IL-18 is a proinflammatory c ytokine that increases in...

Ngày tải lên: 18/06/2014, 19:20