... Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary Corresponding address: Andrew E. Czeizel Foundation for the Community Control of Hereditary Diseases, 1148 Budapest, ... characteristics of the study population, etc. In Hungary the total prevalence of congenital abnormalities was 66.83 per 1000 informative offspring in...
Ngày tải lên: 02/11/2012, 11:12
... Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have the following features: (a) the ability to deliver transgenes in a highly efficient ... applied to humans. The purpose of this paper is to consider the potential for applying the available genetic modification (GM) technologies to the goal of...
Ngày tải lên: 03/11/2012, 10:01
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... the sequences of 1CEV and 1RLA and pasted into the structural alignment. The alignment was then corrected by hand. Since the sequences of the two arginases and agmatinase greately differ in the ... in the case of E. coli agmatinase, of the loop indicated by the letter a. Fig. 5. Scheme of the binuclear manganese cluster and the localization...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
... J. Biochem. 268) q FEBS 2001 Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2 C -methyl-D-erythritol 2,4-cyclodiphosphate in plants Monika Fellermeier 1 , Maja Raschke 1 , ... (2000) Studies on the nonmevalonate pathway: conversion of 4-(cytidine 5 0 -diphospho)-2-C-methyl-D-erythritol to its 2-phos- pho derivative by 4-(cytidi...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... raises the possibility that any one or a combination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity to fractionate lipid emulsions into relatively ... apolipoprotein E3 and E4 to emulsions (Eur. J. Biochem. 269) 5941 Differences in the binding capacity of human apolipoprotein E3 and...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf
... very close to that of the mouse Muc4 (Table 1). The size of intron 1 of the human MUC4 has been estimated to be 15 kb by restriction mapping [12] and to be at least 20 kb by our analysis of the ... in mucin, contained only by the mouse submandibular small mucin [26]. The consensus sequence of the Muc4 tandem repeat is very close to that of SMC....
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: "Redundancy Ratio: An Invariant Property of the Consonant Inventories of the World’s Languages" pdf
... span a much larger range for the vowel inventories than for the consonant inventories. The significance of the difference in the nature of the distribution of RRs for the vowel and the conso- nant ... measure of redun- dancy is almost an invariance over the consonant inventories of the world’s languages. The observa- tion is important since it can s...
Ngày tải lên: 17/03/2014, 04:20
Báo cáo khoa học: Crystal structure and solution characterization of the activation domain of human methionine synthase doc
... measure of the fluorescence intensity in the absence of the activation domain, E 0 is the concentration of the FMN domain, L denotes the concentration of the activation domain added to the sample, and ... proteolytic removal of the N-terminus during purification. Analysis of the interaction between MS activation domain and the FMN domain of...
Ngày tải lên: 23/03/2014, 09:21
Báo cáo y học: "Comprehensibility, reliability, validity, and responsiveness of the Thai version of the Health Assessment Questionnaire in Thai patients with rheumatoid arthritis" potx
... article Comprehensibility, reliability, validity, and responsiveness of the Thai version of the Health Assessment Questionnaire in Thai patients with rheumatoid arthritis Manathip Osiri 1 , Jeerapat Wongchinsri 2 , ... domains). The grip and walking domains of the Thai HAQ also had weak correlations with the number of swollen joints, number...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Longitudinal evaluation the pulmonary function of the pre and postoperative periods in the coronary artery bypass graft surgery of patients treated with a physiotherapy protocol" ppt
... G, Salica A, Frati G, Sani G: Respiratory dysfunction after coronary artery bypass grafting employing bilateral internal mammary arteries: the influence of intact pleura. Eur J Cardiothorac Surg ... postoperative periods in the coronary artery bypass graft surgery of patients treated with a physiotherapy protocol. Journal of Cardiothoracic Surgery...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Successfully treated synchronous double malignancy of the breast and esophagus: a case report" pot
... breast carcinoma. Here, we report an extremely rare case of a patient having carci- noma of the esophagus and the breast at the same time. In this case, the histopathology of the breast tumor was an ... nodes. Significant lymphadenopathy was seen along the celiac trunk and the lesser curvature of the stomach along the gastric artery. The para-aortic...
Ngày tải lên: 11/08/2014, 12:20
Báo cáo y học: "Changes in the mechanical properties of the respiratory system during the development of interstitial lung edema" ppt
... similar model of mild pulmonary edema[20]. Therefore, this study provides the first data concerning modifications in the overall mechanical properties of the respiratory sys- tem in vivo during interstitial ... Contributed in the design of the study, in writing the manuscript, in the design and development of the experi- mental set-up and the da...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: "Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients with systemic sclerosis" pdf
... they are clinically advisable. This study summarises our results in defining a diagnostic approach and analysing the charac- teristics of patients with alveolitis with the aim of identi- fying ... Research Open Access Research Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients...
Ngày tải lên: 12/08/2014, 18:22
Báo cáo y học: " Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness" ppsx
... statistical analyses were done using StatView software (SAS Institute Inc., Cary, NC, USA). Data were analyzed using one-way analysis of variance tests. Data are presented as mean ± standard deviation. ... transport- ers MCT10 and OATP1C1 is increased in the hypotha- lamus of prolonged critically ill rabbits. ã Hypothalamic T3 and T4 levels are not increased in a rabbit model...
Ngày tải lên: 13/08/2014, 19:20
Báo cáo y học: "Polytrauma in the elderly: predictors of the cause and time of death" pdf
... Polytrauma in the elderly: predictors of the cause and time of death Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2010, 18:26 Clement et al. Scandinavian Journal of ... were not analysed in their study. Our study supports this theory identifying those patients with PMC being at an increase risk of inpa- tient mortality that is independent...
Ngày tải lên: 13/08/2014, 23:21