Báo cáo y học: "APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA" pps
Báo cáo y học: "APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA" pps
... respectively. These results indicated that purifying selection pressure was operating against genomes that had inactivating mutations in the gag gene. The observation that a few of the viral RNA-derived sequences ... mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA Rebecca A Russell 1 , Michael D Mo...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "DNA double strand break repair enzymes function at multiple steps in retroviral infection" pptx
... cells. GATGACT TAGCACT TCAGATC CGCCGGG GTCAAGG TTTGAAG TAACTTT ACTTGGG GGACACA GACAGAG GATGTCA GGGCACG TTCAACC CAGGAAT AGCCTGG GCCACCC AGAAGGA GCTGGCA AAGGAAA CTACCAT AACACAC GGGGGAA AGATTAA CTATTAT AGAACCA ACTCAGA AAATTGA TCCTACT ATTAATT GGTATTT CCTCTTT AAAAATG t t t tt tt tt tt tttg tttgg ttacaattcactcttctttcatctaaactcaacatcg g at tgatt aaagcat acacgtgaggc gttttag ataaca a ag c t t ttt...
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: "An MRI study on the relations between muscle atrophy, shoulder function and glenohumeral deformity in shoulders of children with obstetric brachial plexus injury" ppt
... Subluxation was related to both infraspinatus and subscapularis atrophy. There was no relation between atrophy of muscles and passive external rotation. Muscle atrophy was not related to the Mallet ... children with a mean age of 7.7 years, both skeletal deformities and passive external rotation are related to infraspinatus and subscapularis muscle atrophy [7]. Another study f...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Canakinumab (ACZ885, a fully human IgG1 anti-IL-1b mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)" ppsx
... confir- mation of the efficacy of canakinumab in children with this rare disorder and suggest that the safety profile of canakinumab in pediatric patients is similar to that in adults. Safety data for canakinumab ... signs, hematology blood chemistry and urinalysis, and assays for anti-canakinumab antibodies using a binding BIA- core ® assay (Biacore International AB,...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: " APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication" pot
... 5'-ATCCAAGACG- GAATTCGTTTTCCTGATTCTGGAG-3'. The UBA2 gene fragment was amplified from plasmid pcDNA3.1- HHR2 3A by PCR. The 5' primer used was 5'- ATCCAAGACGGAATTCACGCCGCAGGAGAAA- GAAGCTATAG-3'; ... protein band because it only reacts to certain batches of anti-APOBEC3G antibody. To elimi- nate this background, the protein intensity of APOBEC3G-UBA2 and APOBEC3...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury" pps
... mechanical and histological data, statistical analysis, and writing of the manuscript. FFC contributed to animal preparation, performance of exper- imental work, preliminary data analysis, and drafting ... RMs. The increase in different inflammatory mediators after RMs in hypervolemia cannot be explained by increased atelectasis and/ or cyclic opening and closing of collaps...
Ngày tải lên: 13/08/2014, 20:22
Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"
... conditions vary between 28% and 54%. Eosinopenia was a sepsis marker in our study. The study by Gil and colleagues in a department of internal medicine showed that an inflammatory syndrome associated ... and participated in the acquisition of data and the study design. JB participated in the acquisition of data. NM helped to draft the manuscript, and participated...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"
... use of alkalinization, hy- dration and rasburicase at 0.10 mg/kg for 3-5 days maintains the same efficacy. [25] Anyway, we may have favourable issues by changing the dose of ras- buricase, according ... monophosphate (GMP), the purinic nucleotides useful for DNA and RNA synthesis, and inosine that will be degraded into hypoxanthine and xanthine and finally into uric ac...
Ngày tải lên: 31/10/2012, 14:59
Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"
... C-terminal epitope of Vgf. Unoccupied binding sites on the plates were blocked by incubation with casein. Samples and standards were applied in duplicate and incubated overnight at 4°C. Following ... Acad Sci USA 2006; 103(39): 14584-14589. 16. Yamaguchi H, Sasaki K, Satomi Y, Shimbara T, Kageyama H, Mondal MS, Toshinai K, Date Y, Gonzalez LJ, Shioda S, Takao T, Nakazato M,...
Ngày tải lên: 03/11/2012, 10:52