Báo cáo y học: " HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome" pps

... imp7 facilitates nuclear trafficking of DNA and that HIV-1 exploits imp7 to maximize nuclear import of its DNA genome. Lentiviruses other than HIV-1 may have evolved to use alternative nuclear import receptors ... Central Page 1 of 18 (page number not for citation purposes) Retrovirology Open Access Research HIV-1 exploits importin 7 to maximize...

Ngày tải lên: 13/08/2014, 05:21

... to the cystatin superfamily of cysteine protease inhibitors [1, 2]. Cys-C is produced by all nucleated cells and is secreted into the blood at a constant rate [1, 2]. Cys-C is freely filtered ... 289 (7) : 871 – 878 . 20. Hori R, Miyazaki K, Mizugaki M, Ogata H, Goto M, Ichimura F, Yasuhara M, Tanigawara Y, Hashimoto Y, Koue T, Mimaki T, Tanaka K, Okumura K, Gomita H, Higuchi S. Es...

Ngày tải lên: 31/10/2012, 17:08

... conver- sion of a hydroxylase to a desaturase [26]. The objective of our work was to examine the substrate specificity of A. thaliana and B. napus FAE1 KCSs and to study the determinants of fatty acyl chain ... Chimeras of D 6 -fatty acid and D 8 -sphingolipid desaturases. Biochem. Biophys. Res. Commun. 279 , 77 9 78 5. Ó FEBS 2002 Substrate specificity of FAE1 KCSs (Eur. J....

Ngày tải lên: 21/02/2014, 15:20

... drugs. Background Psychotic depression is a clinical subtype of major depres- sive disorder and is characterized by psychosis accompa- nied by relatively severe depressive symptoms that include psychomotor impairment, ... because of the risk of EPS by antipsychotic drugs. More detailed dou- ble-blind studies should be performed to clarify the role of sigma-1 receptors in the efficac...

Ngày tải lên: 08/08/2014, 23:21

... significantly higher incidence in women (6.9; 95% CI = 5.0 to 8.8) than in men (0.5; 95% CI = 0.0 to 1.2) [88]. The prevalence of dry eyes or dry mouth and of primary Sjögren’s syndrome among 52- to 72 -year-old ... population of keratoconjunctivitis sicca was 14.9% (95% CI = 7. 3% to 22.2%), of xerostomia 5.5% (95% CI = 3.0% to 7. 9%), and of autoimmune sialoadenitis a...

Ngày tải lên: 09/08/2014, 14:20

... ≥1:2,560 Total patients Diffuse cytoplasmic only 0 1 7 15 23 Diffuse cytoplasmic + nucleolar 0 4 4 20 28 Diffuse cytoplasmic + nucleolar + others 0 3 2 3 8 Diffuse cytoplasmic + others 2 8 11 22 43 Total ... Hanyang University Medical Center, 133 -79 2 Seoul, Republic of Korea Corresponding author: Think-You Kim, tykim@hanyang.ac.kr Published: 15 June 2009 Arthritis Research & Therapy...

Ngày tải lên: 09/08/2014, 14:21

... 60,846 ,73 8.1 37. 1 Upstream of ZNF581 Yes 16 60,856, 978 .7 23.4 Upstream of U2AF2 Yes 17 60, 878 ,268.6 125.4 60, 878 ,250.5 -18.1 18.1 Upstream EPN1 Yes 18 60, 878 ,368 .7 105.4 60, 878 ,386.5 17. 8 17. 8 Upstream ... 60,838,196 60,846,664 60,846 ,79 4 60,8 57, 070 60, 878 ,251 60, 878 ,250 60, 878 ,292 60, 878 ,366 60, 878 ,3 87 60, 878 ,388 61,5 17, 979 61,518,050 61,518,051...

Ngày tải lên: 09/08/2014, 20:21

... number of genes significantly higher in liver ( 47% ) and kidney (53%). By contrast, the standard nor- malization (to the total number of reads as originally used in [6]) result s in the majority of ... ) * * log () 2 2 TMM w gk r M gk r gG w gk r gG M Y gk N k k r gk r         where               log ; , 2 Y gr N r w N k Y gk N k Y gk N r Y gr N r Y...

Ngày tải lên: 09/08/2014, 20:21

... gametophyte (pollen) development is dominated by the activity of MIKC*-group genes (blue) and the development of the female gametophyte (embryo sac), embryo and seed is mainly controlled by type ... deacetylation of histones at its locus, the reduction of repressive histone methylations and increase of activat- ing histone methylations at VRN1 lead to activa tion of this...

Ngày tải lên: 09/08/2014, 20:22

... evascu- larisation. The physiologic basis of extra-anatomic bypass reveals that inflow in the donor artery is the key factor that determines the haemodynamic effects of extra-anatomic bypass. If the inflow ... Nashef Journal of Cardiothoracic Surgery 2010, 5 :73 http://www.cardiothoracicsurgery.org/content/5/1 /73 Page 3 of 4 Case 2 A 49-year-old female smoker presented with a two-y...

Ngày tải lên: 10/08/2014, 09:22