Báo cáo y học: "Determinants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivo" doc

... boost HIV-1 spread in HIV-1- infected HLAC and identify two inde- pendent protein interaction motifs in Nef that facilitate CD4 + T lymphocyte depletion independently of their effect on HIV-1 replication. Nef ... human lymphoid tissue: correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syn- cytium-inducing phenotype in histocultures...

Ngày tải lên: 13/08/2014, 05:21

... RA and PGIA suggest that certain as-yet-unknown alterations of the immune system exist in both humans and mice. As a continuation of the experiments presented in this study, we are comparing ... colonies/substrains (for example, in body weight, size of littermates, and the composition of intestinal bacterial flora) maintained at different locations by the same vendor. Acc...

Ngày tải lên: 09/08/2014, 01:22

... apoptosis of phagocytes, resulting in either control of intracellular growth of the bacteria or evasion of the immune system [14]. Based on the results of the present study, it is difficult to tell ... by flow cytometryFigure 6 Analysis of the nuclear DNA fragmentation in L. pneumophila-infected A549 cells by flow cytometry. Two days after treatment, A549 cells were treated...

Ngày tải lên: 12/08/2014, 15:21

... assistants to carry out clinical chemistry assays. Both authors read and approved the final version of the manuscript. Competing interests The authors declare that they have no competing interests. Received: ... (5-HPETE), and subsequently into the epoxide intermediate leukotriene A4 (LTA4). Hydrolysis of LTA4 by LTA4 hydrolase leads to the formation of the potent neutrophil che- mo...

Ngày tải lên: 13/08/2014, 14:20

... presence of intrauterine pregnancy, can be an important aid in the diagnosis of HP [1]. Further, visualization of heart activity in both intrauterine and extrauterine gestation confirms the diagnosis ... condition of the patient. The main aim of the surgery should be the preservation of the intrauterine pregnancy with minimal manipulation of the uterus. Medical treatment...

Ngày tải lên: 11/08/2014, 14:20

... recruits at the first stage were due to delays in GP pract ices sending letters out after the notes searches, the short time window of intensive recruitment and that fact th at the start date of the ... intervention and conduct of the trial. Feasibility of recruitment Recruitment into trials for mental health interventions is notoriously difficult [26]. Gaining interest in t...

Ngày tải lên: 11/08/2014, 15:22

... risk profile of the patient at the time of acute MI, the absence of symptoms after the event and the absence of inducible ischaemia during the treadmill exercise test and decided that a non-invasive ... report and accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Competing interests The authors declare that...

Ngày tải lên: 11/08/2014, 19:21

... that the two main techniques used to detect protein-protein interactions, namely yeast two- hybrid and affinity-purification-coupled mass spectrometry are of high quality and of complementary ... use in further experimental investigation. Finally, we were also able to estimate the extent of interlocking between other major regulatory systems such as transcription and the ubiquit...

Ngày tải lên: 14/08/2014, 21:20

... the content of a topic or to interactively expand a topic with newly computed related topics. In the first step, the topic graph is computed on the y from the a set of web snippets that has been collected ... actually labeled with the specific relation that exists between the nodes. In this way the user can explore in an uniform way both new information nuggets and validated back-...

Ngày tải lên: 20/02/2014, 05:20

... forbidden except the designated train- ing corpus. In order to test the performance of the lexical-target templates and meanwhile determine the best iterations over the training corpus, we ran- domly ... and multi- character word respectively. In order to perform POS tagging at the same time, we expand boundary tags to include POS information by attaching a POS to the tail of a bo...

Ngày tải lên: 08/03/2014, 01:20