Báo cáo y học: "Human prostate supports more efficient replication of HIV-1 R5 than X4 strains ex vivo" pdf

... rectosig- moid explants supported efficient replication by both R5 and X4 strains, tonsil explants, which displayed low num- bers of CCR5+ cells, were less efficiently infected by R5 strains [40]. ... infection of human prostate in organotypic cultureFigure 3 HIV-1 R5, R 5X4 and X4 infection of human prostate in organotypic culture. RT activity was measured in sup...

Ngày tải lên: 13/08/2014, 05:21

... previously described [20]. Determination of pulmonary function by whole-body plethysmography Whole-body plethysmography (Buxco Electronics Inc. Troy, NY) was used, to monitor the respiratory dynamics of ... At day 4 p.i., NK cell cytotoxicity was assessed by direct ex vivo cytotoxicity of BAL cells against YAC-1 target cells. NK cell activity was significantly higher after infection...

Ngày tải lên: 12/08/2014, 15:20

... cel- lular components of inflamed synovium consist of inflammatory cells, predominantly macrophages, T lymphocytes, and an overgrowth of synovial fibroblasts. RA synovial fibroblasts are key mediators ... associ- ated with delayed-type hypersensitivity. Science 1966, 153:80-82. 24. David JR: Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell...

Ngày tải lên: 09/08/2014, 08:22

... multiple determinants: gene expression and protein length, for instance [34]. Here, we find that a total of approximately 20% of the variability in F op is explained by gene expression (meas- ured by expressed ... frequency of these newly defined optimal codons (hereafter denoted F op ) is more strongly cor- related with the level of gene expression than was the case in previous...

Ngày tải lên: 09/08/2014, 20:20

... facility to complete a four week course of antibiotics. Discussion This case illustrates the importance of an index of suspi- cion for the diagnosis of Lyme involvement of the central nervous system ... the importance of a high index of clinical suspicion in detection of Lyme disease related manifestations in endemic areas. Background Lyme disease is a multisystem inflammatory...

Ngày tải lên: 11/08/2014, 10:22

... oratory trials of a range of different individual and group-based arts therapies. The MATISSE study provides an opportunity to examine the impact of an arts therapy when offered to a wider group of ... P, Farmer A, Harvey I: A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Arch Gen Psychiatry...

Ngày tải lên: 11/08/2014, 16:22

... locus. A. The cytosine methylation profile of ERV mch8 in the cerebellum was compared to the methylation profile of an amalgamation of other brain compartments (cerebral cortex, corpus callosum, ... Takayuki Itoh 2,3 , David G. Greenhalgh 1,3 , and Kiho Cho 1,3 * 1 Department of Surgery, University of California, Davis, Sacramento, CA, USA 2 Department of Neurology, Univer...

Ngày tải lên: 13/08/2014, 01:21

... likely that downmodulation of CD4 has a greater impact on X4 HIV-1 replication than on R5 HIV-1 replication. R5 HIV-1 Nef may therefore have a greater positive effect on viral replication by down-modulating ... thereby protecting infected cells from lysis by anti -HIV-1 cytotoxic T lymphocytes. Moreover, because R5 HIV-1 clones preferentially infect effector memory T...

Ngày tải lên: 13/08/2014, 05:20

... coronary syndromes [45,46]. Heart-type fatty acid binding protein Heart-type fatty acid binding protein (H-FABP) is a small cytosolic protein found in cardiomyocytes responsible for fatty acid ... enzymes, the uses of which were restricted to the diagnosis of acute myocardial infarction (cardiac necrosis). The discovery of new cardiac biomarkers and the increased sensitivity of the as...

Ngày tải lên: 13/08/2014, 10:20

... modulate memory [8]. Other systems could modulate the formation of emotionally motivated memory. For example, opioid receptors are involved in memory modulation, and post-training injections of the ... few years have been the Morris water maze, one-trial inhibitory avoid- ance, and various forms of fear conditioning, all of which closely mimic human situations of daily life. The inh...

Ngày tải lên: 13/08/2014, 11:23