Báo cáo y học: "Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm" pps

... anchor themselves to the target membrane through their hydrophobic segments and then fold back, bringing the viral and cellular membranes together and forcing their merger. However, the pathways of ... Institute of Human Virology, Department of Microbiology and Immunology, University of Maryland School of Medicine, 725 W. Lombard St, Baltimore, MD 21201, USA Email:...

Ngày tải lên: 13/08/2014, 05:21

... entry of free viruses, and the maturation or egress of the virus [8,9]. Glycoprotein K is one of the major glycoproteins encoded by the DEV-gK gene, which is located in the unique long region of ... is the first time to product and purify the rabbit anti-tgK polyclonal antibody. Through the western blot and ELISA assay, the truncated glycoprotein K (tgK) has go...

Ngày tải lên: 12/08/2014, 01:21

... nearly 300 years ago, and the divergence of the four HMPV genotypes likely occurred within the last hun- dred years. de Graaf et al recently reported estimated tMRCA values of ~120 years for the ... to other paramyxovi- ruses. RNA viruses mutate frequently due to the infidelity and lack of proofreading ability of RNA-dependent RNA polymerases [38]. Our data confirm that...

Ngày tải lên: 12/08/2014, 04:20

... approach to the poisoned patient. In my service, the use of the EOU in the care of the poisoned patient had dramatically improved care and reduced length of stay. With a structured approach to these ... suggestive of the diagnosis [10], and its diagnosis and management is well detailed by Boyle's article. Toxicology in Australia In Australian there has been the...

Ngày tải lên: 13/08/2014, 23:20

... orthopedists, and physical therapists. Yet this disorder of the muscle system is routinely ignored in the diagnosis and treatment of these patients. The diagnosis of muscular imbalance with the MMT may offer ... accurately diag- nose the cause of pain in only some 10% of patients [74]. The use of the MMT for the diagnosis of musculoskeletal dysfunction has al...

Ngày tải lên: 13/08/2014, 14:20

... publication to the time of the search were identified. The number of citations per year from the year of publication to the study pe- riod was calculated for each article (citations per year). Statistical ... publication, country of origin, type of cancer, sample size, number of polymorphisms tested and results of the study. Studies were divided into two categ...

Ngày tải lên: 25/10/2012, 10:51

... on the prevalence of hyperopia and myopia. As age increased, the prevalence of hyperopia signif- icantly decreased and the prevalence of myopia in - creased. Based on the definitions of hyperopia ... hyperopia and myopia: as age increased, the prevalence of hyperopia markedly decreased, and that of myopia significantly increased. The prevalence of hyperop...

Ngày tải lên: 25/10/2012, 11:40

... synthesized by chondrocytes and FLS. These cytokines act in various ways in the pathogenesis of OA such as inhibition o f s y nth esi s o f type 2 (articular) cartilage and activation of catabolic ... design of the project and data analysis, and was primarily responsible for writing the manuscript. KVA contributed to the de- sign of the project, patient recruit...

Ngày tải lên: 25/10/2012, 11:40

... A ˚ ke Engstro ¨ m at the Peptide Synthesis and Analysis Laboratory of the Department of Medical Biochemistry and Microbio- logy, Uppsala University. The SP6 primer 5¢-ATT TAG GTG ACA CTA TAG-3¢ and the three ... other combinations of phosphatases and interme- diary phosphorylated enzymes. Therefore, kinetic data on the dephosphorylation of autophosphorylated ATP-cit...

Ngày tải lên: 21/02/2014, 01:21

... [64] have studied the promoter activity and wound-induction of HRPC and -E types, and of AtPCa and AtPEa. Most remarkably, C2, and only C2, responded strongly to wounding. The AtP38 gene might respond ... a nonglycosylated triplet at position Asn70 [48]. The majority of the peroxidases carry one or two putative glycans. Seven appear to be nonglycosylated. Therefore, t...

Ngày tải lên: 21/02/2014, 01:21