Báo cáo y học: " Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes" ppsx

... removes the DNA-binding domain in the amino-terminus of p65/RelA by cleavage at a sequence near a caspase-3 cleavage site, leaving a carboxy-terminal fragment that contains two potent transactivation ... purposes) Retrovirology Open Access Research Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα a...

Ngày tải lên: 13/08/2014, 05:21

... laboratory work, interpre- tation of data and manuscript writing. AZ contributed to patient characterization, acquisition of data and statistics. TS contributed to the original idea, interpretation ... interpretation of data and man- uscript writing. JW contributed to interpretation of data, statis- tics and manuscript writing. IG contributed to patient characterization, acqui...

Ngày tải lên: 12/08/2014, 11:22

... activate the MAPK pathway. MAP kinases and STAT3 are rapidly activated within 10 min in response to Hyper-CNTF, the phase of activation lasting for at least 30 min before returning to near basal levels ... MAPK activation by Hyper-CNTF in transfected BAF/3 cells Downstream signal transduction pathways were analyzed by studying the activation level of JAK/STAT and MAP kinase signal...

Ngày tải lên: 22/02/2014, 07:20

... oral tolerance test results. 16 Interestingly, and similarly to patients with aspirin-exacerbated respiratory disease (AERD), in patients with acute urticaria induced by distinct NSAIDs (both with and without ... inflammatory processes, and there is some evidence that they may act as mediators in urticaria. Their intradermal injection elicits a wheal and flare reaction eithe...

Ngày tải lên: 08/08/2014, 21:20

... conceived the study, and participated in its design, acquisition, analysis and interpretation of data, and in the drafting of the manuscript. OO participated in its coordi- nation, statistical analysis ... Abstract Background: The aim of this study is to evaluate the effect of a psychiatric label attached to an apparently normal person on the attitude of final year me...

Ngày tải lên: 08/08/2014, 23:21

... which an admix of inflammatory and scarring tissue damage is often present. On the other hand, MSCs may also actively participate in initiating AD [3], they have the potential to favour spread of melanoma ... potential synergy and interdisciplinary collaboration. As pointed out by the director of the institute, Marc Feldmann, following the rapidly growing activity in the past fe...

Ngày tải lên: 09/08/2014, 08:23

... GCATCGTAGGTCTGTCCTG 364 MMP-3 S: GAAAGTCTGGGAAGAGGTGACTCCAC AS: CAGTGTTGGCTGAGTGAAAGAGACCC 284 Osteocalcin S: CATGAGAGCCCTCACA AS: AGAGCGACACCCTAGAC 310 [48] Alkaline phosphatase S: TGCAGTACGAGCTGAACAG AS: ... TGCAGTACGAGCTGAACAG AS: TGAAGACGTGGGAATGGTC 267 Type I collagen α1 chain S: CCGAAGGTTCCCCTGGACGA AS: CGCCCTGTTCGCCTGTCTCA 252 18S S: GAATCAGGGTTCGATTCCG AS: CCAAGATCCAACTACGAGC 279 [29]...

Ngày tải lên: 09/08/2014, 10:20

... vivo assessment. Introduction Although articular cartilage shows durability and the ability to maintain itself, it has limited capacity for repair [1,2]. The repair cartilage that forms as a result of articular injury ... Assessment of rat articular cartilage matura- tion using 50-MHz quantitative ultrasonography. Osteoarthritis Cartilage 2001, 9:178-186. 20. Hattori K, Ikeuchi K, M...

Ngày tải lên: 09/08/2014, 10:21

... 5'-TTTTC- CTTTTGCGGCCGCTCATTAGTTTC- GTATCTTCATTGTCATGTA-3', which appended part of a 15 amino acid linker (SSSSG) 3 at its N-terminus and a stop codon and NotI restriction site at its C-terminus. The ... protein L19-IL10 using the following primer sequences: a backward antisense primer, 5' TAATGGTGATGGTGATGGTGGTTTCGTATCTTCATTGT- CATGTAGGCTTC-3'; and a forw...

Ngày tải lên: 09/08/2014, 14:22

... metazoans/choanoflagellates. In metazoans, but not in choanoflagellates, some cadherins also con- tain an intracellular catenin-binding domain (CBD) that connects intercellular binding via EC domains to intra- cellular ... highlighting that the CRN family, greatly expanded in Phytophthora [28], had already evolved in the last commo n ancest or of P. ultimum and Phytophthora....

Ngày tải lên: 09/08/2014, 20:22