Báo cáo y học: "Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model" pptx

... Access Research Activation and detection of HTLV -I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model Takashi Ohashi*, Mika Nagai, Hiroyuki Okada, Ryo Takayanagi ... Ohashi T, Hanabuchi S, Kato H, Koya Y, Takemura F, Hirokawa K, Yoshiki T, Tanaka Y, Fujii M, Kannagi M: Induction of adult T-cell leukemia-like lym...

Ngày tải lên: 13/08/2014, 05:21

... growth factor beta inhibitory Smads 6 and 7 are expressed in human adult normal and osteoarthritic cartilage in vivo and are differentially regulated in vitro by interleukin-1beta. Arthritis Rheum ... publications that FGF-2 stimulates catabolism and/ or anti-anabolism by inducing cartilage degrading enzymes (e.g., MMP1, MMP13) and proteoglycan loss in articular carti...

Ngày tải lên: 12/08/2014, 17:22

... patients and control individuals, and examined whether TGF-β 1 activation was associated with clinical phenotype, in particular inflammatory disease activity, cumulative organ damage and early atherosclerosis. Materials ... SLE patients and control individuals within the context of inflammatory disease activity, cumulative organ damage and early atherosclerosis. An Activation I...

Ngày tải lên: 09/08/2014, 08:22

... appear to have repair capacity in animals and humans, especially in young individuals [2,3,5- 8]. Repair of full thickness JSDs involves coordination of pat- terning and tissue maturation that ... and injured (B) articular cartilage 6 days after the operation. The asterisk indicates the site of injury (occupied by debris). The dashed line indicates the margin of the inju...

Ngày tải lên: 09/08/2014, 08:22

... 3 Profiling gelatinase gene expression and gelatinolytic activity in resorbing cartilageProfiling gelatinase gene expression and gelatinolytic activity in resorbing cartilage. Bovine nasal cartilage ... 37°C, and one unit of inhibitory activity inhibits two units of collagenase by 50%. Gelatinase activity in the culture supernatants was assayed by gelatin zymography. Sampl...

Ngày tải lên: 09/08/2014, 08:22

... participated in study design, acquisition of data, analysis and interpretation of data, statistical analysis, and manuscript preparation. NA participated in acquisition of data, analysis and interpretation ... interpretation of data, statistical analysis, and manuscript preparation. JMP and JPP participated in study design, analy- sis and interpretation of data, a...

Ngày tải lên: 09/08/2014, 10:22

... detection of expression levels and coding-sequence variation in a single analysis pipeline will be beneficial for patient- sample analysis. We have implemented our method in a software called SplitSeek. ... gene fusionsinanRNAsampleinacompletelyunbiased way. We also want to emphasize the possibility of find- ing insertions, deletions, and o ther types of genetic rearrangem...

Ngày tải lên: 09/08/2014, 20:21

... of 7 Plasma levels of pro and anti-inflammatory cytokines Plasma levels of IL-6, TNF -a and IFN-g were significantly higher in patients; t he levels of the anti-infl ammatory cytokines IL-10 and ... plasma levels of anti-inflammatory and inflammatory cytokines including interleukin-6 (IL- 6), IFN-g, IL-10 and transforming growth factor-beta (TGF-b) in p atients with p...

Ngày tải lên: 11/08/2014, 03:20

... Virology Section, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0460, USA Email: Jia Hai ... study and wrote the manuscript. Acknowledgements Work in Kuan-Teh Jeang's laboratory is supported in part by intramural funding from NIAID, NIH; and by the intramural AIDS...

Ngày tải lên: 13/08/2014, 05:22

... assembly by Nakabayashi and Sasaki [75] at the parameter values considered in this study exhibits a characteristic time delay on the order of 100 min. A simple improvement is the delayed initiation of ... Furthermore, as implicated by the synthesis rate of its inactive form, Smac*, and correspond- ingly its target XIAP, plays a vital role in achieving the correct activ...

Ngày tải lên: 13/08/2014, 16:21