Báo cáo y học: "HLA-C increases HIV-1 infectivity and is associated with gp120" pot

... fusion assay where CHO and CHO-HLA-C cells, transiently transfected with gp120/gp41 from different primary and laboratory HIV-1 isolates, were fused with TZM-bl cells and fusion quantified by luciferase ... analyzed by co-cultivating cell lines expressing HIV-1 gp120/gp41 from different laboratory and primary isolates with target cells expressing different HIV-1 co-recepto...

Ngày tải lên: 13/08/2014, 05:21

... events by the number of bead events and subsequently multiplying by the TRUCOUNT ® bead concentration. HLA BRB1 genotyping and statistical analysis was per- formed as described previously [27] ... peripheral lymphocytes is plotted on the x axis, and the number of patients in each frequency range is plotted on the y axis. The overlays represent the Gaussian frequency distributions...

Ngày tải lên: 09/08/2014, 03:24

... pubic symphysis and articular cartilage explants was similarly subjected to western blot analysis for collagenase-1 and stromelysin-1. Substrate zymography Enzyme activities were quantified by substrate ... joint (TMJ) disc, and the pubic symphysis. Within the pubic symphysis of several species, the repro- ductive hormone relaxin induces matrix remodeling activity during pregnancy and...

Ngày tải lên: 09/08/2014, 06:22

... randomly selected and matched for sex and age within a range of 5 years. The mean age of the controls was 58.2 years (range 25–79 years), and the distribution of males and females was 26.3% and ... 1858C/T polymorphism and early RA in patients from northern Sweden, related the polymorphism to autoantibodies and the HLA-DR shared epitope, and analysed their association with m...

Ngày tải lên: 09/08/2014, 10:20

... encoded by the ITGAV gene, plays a key role in angiogenesis. Hyperangiogenesis is involved in rheumatoid arthritis (RA) and the ITGAV gene is located in 2q31, one of the suggested RA susceptibility ... heterozygote parents. Table 3 Genotype relative risk analysis for single nucleotide polymorphism (SNP)1 and SNP2 in sample 1 of rheumatoid arthritis trio families Genotype Rheumatoid a...

Ngày tải lên: 09/08/2014, 10:20

... performed data analysis. FC and SDavis were responsible for study design and data analysis and interpretation and SDavison reviewed the final draft. All authors prepared, read and approved the ... relatively large number of study participants, and measurement of CRP by a highly sen- sitive assay. A potential limitation of this study is that hsCRP was only measured on one occasio...

Ngày tải lên: 09/08/2014, 10:23

... patients were younger than 60 years old. Male and female patients were 30 and 44, separately. Twenty nine patients were diagnosed with B symptoms, 50 patients had stage III-IV diseases and 50 patients ... survival, differentiation, and prolife ration (e.g. c-myc, cyclin D1, p21, cyclin E), invasion and metastasis (e.g. matrix metalloproteinase-9 and 2)[19], and angiogenesis (e...

Ngày tải lên: 10/08/2014, 21:23

... co-morbidity with generalized anxiety disor- der, panic disorder, depressive disorders, and bipolar disorder in adults [9]. Asthma is to a similar degree associated with the same anxiety disorders and with bipolar ... comprehensive understanding of this disorder is still lacking. Pelsser, Buitelaar & Savelkoul [22] have advanced the hypothesis that ADHD may be a non-allerg...

Ngày tải lên: 11/08/2014, 15:22

... resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study Miranda L Davies-Tuck 1 , Anita E Wluka 1,2 , Andrew Forbes 1 , Yuanyuan ... surgery (including arthroscopy); a history of any form of arthritis diagnosed by a medical practitioner or a contraindication to MRI, as previously described [33]. The study was approved...

Ngày tải lên: 12/08/2014, 11:22

... nasal polyps by immunohistochemistry In order to determine the phosphorylation status of mTOR in nasal tissues, pmTOR expression was examined by immunohistochemistry (Figure 1A, B, C, D) and pmTOR+ ... chronic rhinosinusitis without nasal polyps (CRSnNP) or with nasal polyps (CRSwNP) [1]. CRSwNP is characterized by polyp formation and mixed types of Th1/Th2 infiltrates and their co...

Ngày tải lên: 12/08/2014, 14:20