Báo cáo y học: " Regulation of primate lentiviral RNA dimerization by structural entrapment" ppt

... Central Page 1 of 16 (page number not for citation purposes) Retrovirology Open Access Research Regulation of primate lentiviral RNA dimerization by structural entrapment Tayyba T Baig, Christy L Strong, ... hours of culture [52], the majority of their genomic RNAs may have been matured by slow-acting dimerization site(s), which may explain why most of their SL1 m...

Ngày tải lên: 13/08/2014, 05:21

... everyday practice, because the emergency management of UAE is only seldom undertaken by an ENT department. Indirect laryngo- scopy, a more straightforward method for the evaluation of the larynx, ... management of hereditary angioedema. Allergy Asthma Proc 2009, 30(3):338-42. 41. Farkas H, Gyeney L, Gidofalvy E, Fust G, Varga L: The efficacy of short-term danazol prophylaxis in here...

Ngày tải lên: 08/08/2014, 21:20

... exclusively but, rather, by a set of different proteins that are structurally related [1]. The promoter regions of many eukaryotic genes contain GC-rich sequences [2] and some of the most widely distributed ... identification by Bigey et al.ofmany Correspondence to K. K. Yokoyama, Gene Engineering Division, Department of Biological Systems, BioResource Center, Tsukuba Institute, RI...

Ngày tải lên: 22/02/2014, 07:20

... responsible for the hyperacute vascular rejection occurring in pig-to-primates organ trans- plantation. The synthesis of the aGal epitope is catalyzed by the enzyme a1,3-galactosyltransferase (a1,3GalT). ... the Prime-a-gene labeling system (Promega). Double-positive clones were purified by secondary and tertiary r ounds of screening and genomic DNA inserts were purified using poly(ethy...

Ngày tải lên: 08/03/2014, 16:20

... study down -regulation of the RAS–ERK signalling p athway and other functions of RAS. Down -regulation of the RAS– ERK pathway may be a critical step in the process of end- stage megakaryocyte ... ngÆmL )1 TPO. (A) Platelets were lysed b y the addition of denat- urating lysis buffer. Proteins of whole cell lysate were resolved by 10% SDS/PAGE and analysed by Western blottin...

Ngày tải lên: 08/03/2014, 16:20

... phosphatases in the regulation of yeast SAPK pathways, then fo cus on the properties of the protein phosphatases implicated in the mammalian SAPK systems. REGULATION OF SAPK SIGNAL PATHWAYS BY PROTEIN PHOSPHATASES ... phosphorylation of conserved tyrosine and threonine residues within the catalytic domain. This phosphorylation is mediated by dual specificity protein kinases, me...

Ngày tải lên: 17/03/2014, 23:20

... cells by single step method of Chomczynski & Sacchi [36] using trizol reagent. The integrity and quality of purified RNA were con- trolled by 1% agarose gel electrophoresis and measure of the ... by relative quantitative RT-PCR as described previously in [24]. Glyp-1, glypican-1; synd-1, syndecan-1; synd-4, syndecan-4. (A) Agarose gel of one representative experiment. (B) D...

Ngày tải lên: 17/03/2014, 23:20

... ADP-ribosylated by diphtheria toxin [25]. ADP-ribosylation inhibits the activity of eEF2. Phosphorylation of eEF2 inhibits its activity, in translo- cation and in poly(U)-directed polyphenylalanine synthesis [26,27], ... the phosphorylation of the valyl-tRNA synthetase that associates with eEF1A/B. The available evidence suggests that phosphorylation of eEF1A/B and of valyl- tRNA...

Ngày tải lên: 23/03/2014, 21:20

... Thr70, the sites most profoundly affected by rapamycin, may be regulated by nutrients through the mTOR pathway. REGULATION OF 4E-BP1 BY AMINO ACIDS In a number of kinds of mammalian cells, amino ... primarily by 1-leucine in isolated adipocytes. Am. J. Physiol. 44, C1232–C1238. 109. Lynch, C.J. (2001) Role of leucine in the regulation of mTOR by amino acids: revelation...

Ngày tải lên: 23/03/2014, 21:20

... under- standing of the mechanism of hypoxia-induced NFκB activity. The fact that the inhibitory action of hydroxylases is at the level of the IKK complex through suppression of catalytic activity means ... the level of the IKK complex. NFκB is also activated by ultraviolet light [14,15], by oxidative stress [16], by shear stress [17] and by other mechanisms. NF κκ B, hypox...

Ngày tải lên: 09/08/2014, 01:22