Báo cáo y học: "Trypanosoma cruzi (Chagas'''''''' disease ag

Báo cáo y học: "Trypanosoma cruzi (Chagas'''' disease agent) reduces HIV-1 replication in human placenta" pps

... modify the placental environment. In fact, many soluble factors, including cytokines and hormones, with regulatory activities are essential for establishing and maintaining pregnancy [45,46]. HIV-1 ... may stimulate HIV-1 replication in different cell types [52,53], although mechanisms are not clearly defined. In our system, a diminished secre- tion of those stimulatory cytokines/...

Ngày tải lên : 13/08/2014, 05:21

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Báo cáo Y học: Effect of the disease-causing mutations identiﬁed in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot

... protein without seriously affecting the substrate binding afﬁnity. Binding analyses using BIAcore system To examine whether the mutation of Gly10 to Leu or Pro affects the substrate binding afﬁnity ... for Tk-G10S. Binding analysis of proteins to RNA ⁄ DNA hybrid Binding of the proteins to the substrate was analyzed using the Biacore X instrument (Biacore, Uppsala, Sweden). Twenty-nine bp [rA...

Ngày tải lên : 17/03/2014, 17:20

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Báo cáo y học: "The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study" pptx

... C-reactive protein; CVD = cardiovascular disease; DAS28 = disease activity score of 28 joints; DMARD = disease- modifying anti-rheumatic drug; ELISA = enzyme-linked immunosorbent assay; HAQ = Stanford ... data from the 10-year follow-up examination, which gave the oppor- tunity of controlling not only for cardiovascular risk factors, including body mass index (BMI) and creatinine levels,...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"

... ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut mucosa to endotoxins [43, 44]. These factors are involved in ethanol-induced ... approach when considering the reported high expression of the ankyrin-repeat oncoprotein (gankyrin) in human hepatocellular carcinoma . Gankyrin binds to the cell-cycle regulator...

Ngày tải lên : 31/10/2012, 15:28

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Tài liệu Báo cáo Y học: Regulated expression and intracellular localization of cystatin F in human U937 cells pptx

... approximately 120 amino acids long and contain at least two disulﬁde bridges. Type 3 cystatins, the kininogens, are larger proteins containing three tandemly repeated type 2-like cystatin domains. Type ... and 88–90 (cystatin C numbering). Recombinant cystatin F expressed in Sf9 insect cells is indeed glycosylated [5]. Compared to other cystatins, cystatin F is an unusually speciﬁc inhibito...

Ngày tải lên : 21/02/2014, 01:21

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Báo cáo y học: "Elucidation of the potential roles of matrix metalloproteinases in skeletal biology" pps

... biological function of the enzyme. Indeed, the null mutation in MMP-2 engineered in mice results in a very mild phenotype, manifested mainly by a decrease in bone length [9]. It has been ... of MMP-2, the clinical phenotype is not yet explained. We still do not know precisely what role MMP-2 plays in human biological processes. In vitro MMP-2 can cleave type I and type IV co...

Ngày tải lên : 09/08/2014, 01:21

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Báo cáo y học: "The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein" doc

... albumin; CICP = carboxy-terminal peptide fragment of col- lagen type I; COX-2 = cyclooxygenase-2; ELISA = enzyme-linked immunosorbent assay; FLAP = 5-lipoxygenase-activating protein; GAPDH = glyc- eraldehyde-3-phosphate ... IL-18- dependent pathway in other cell systems. Indeed, PGE 2 - driven IL-10 synthesis in monocytes/macrophages in vitro has been shown to inhibit LTB 4 production...

Ngày tải lên : 09/08/2014, 08:23

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Báo cáo y học: "Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes" doc

... proliferator-activated receptor γ inhibits interleukin-1β-induced membrane- associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. J Biol Chem 2004, ... of mitogen-activated protein kinases and tyrosine kinases on IL- 1-induced NF-κB activation and iNOS expression in bovine articular chondrocytes. Nitric Oxide 2002, 6:35-44. 40. Liac...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis" ppsx

... found in all the stained RA synovial biopsies. FcγRIIb staining was observed in the synovial lining and sub-lining layers, perivasculary and inside lymphocyte infiltrates (e). (d) No staining ... synovial lining and sub-lining layers and perivasculary. Note the dense staining of FcγRIII in the synovial lining layer. The FcγR stainings were rep- resentative of all other RA tissues st...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "Expression and function of junctional adhesion molecule-C in human and experimental arthritis" pot

... transfer-induced arthritis. JAM-C was expressed by synovial fibroblasts in the lining layer and associated with vessels in the sublining layer in human and mouse arthritic synovial tissue. In human ... was mainly found in the lining layer and was associated with vessels in the sublining layer (Figure 1a,b) in OA and in RA synovial biopsies. JAM-C expression, as quantified...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "Trypanosoma cruzi (Chagas'''''''' disease agent) reduces HIV-1 replication in human placenta" pps

Báo cáo y học: "Trypanosoma cruzi (Chagas'''' disease agent) reduces HIV-1 replication in human placenta" pps

Báo cáo Y học: Effect of the disease-causing mutations identiﬁed in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot