Báo cáo y học: " Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR" pdf

Báo cáo y học: " Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR" pdf

Báo cáo y học: " Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR" pdf

... Central Page 1 of 13 (page number not for citation purposes) Retrovirology Open Access Research Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR Rachel Van Duyne 1 , ... Abstract Background: The rate of transcription of the HIV-1 viral genome is mediated by the interaction of the viral protein Tat with the LTR...
Ngày tải lên : 13/08/2014, 05:20
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Báo cáo Y học: A critical motif for oligomerization and chaperone activity of bacterial a-heat shock proteins pot

Báo cáo Y học: A critical motif for oligomerization and chaperone activity of bacterial a-heat shock proteins pot

... determined by the Bradford assay. All protein concentrations reported in this study are expressed in terms of protomers. Chaperone activity assay Chaperone activity was determined by the citrate synthase (CS) ... point mutations within the N- and C-terminal regions and analyzed them by gel filtration, citrate synthase assay and coaffinity purification. Truncation of more than the...
Ngày tải lên : 31/03/2014, 21:21
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Báo cáo y học: " Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study" pdf

Báo cáo y học: " Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study" pdf

... It appears that the degree of systemic inflammation in COPD is independent of the level of airway neutrophils. There are multiple mechanisms by which neutrophils may be recruited into the airways. Thus, ... hospitalization). At baseline, the patients were asked about the frequency of exacerbations in the previous year. The number of exacerbations during the year afte...
Ngày tải lên : 12/08/2014, 11:22
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Báo cáo y học: "Subtype-associated differences in HIV-1 reverse transcription affect the viral replication" ppt

Báo cáo y học: "Subtype-associated differences in HIV-1 reverse transcription affect the viral replication" ppt

... requency of polymorphisms was calcu- lated as a mean of the number of mutations per nucleo- tide for each viral genome. Analysis of synonymous versus nonsynonymous mutations relative to the initial HIV-1 ... structures in the finger subdomain of RT [28]. Our analysis of the poten- tial effect of the detected AA changes in the RT poly- merase domains of B and C...
Ngày tải lên : 13/08/2014, 01:20
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Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx

Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx

... Among G6PD-deficient erythrocytes, aged cells are the most sensitive to haemolysis, because of age-dependent decay of the activity of several enzymes, including G6PD, and antioxidant systems. There is further ... next evaluated the effects of such treatment on isoaspartate formation, by measuring the levels of mem- brane protein methyl esters by the in situ methylation...
Ngày tải lên : 08/03/2014, 22:20
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Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"

Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"

... detailed haemodynamic assessment by transpul- monary thermodilution technique (PiCCO system). Surpris- ingly, none of the measured angiogenic factors correlated with any of the haemodynamic parameters ... affinity to the extracellular domain of the Tie2 receptor, which is almost exclusively expressed by endothelial cells. Binding of the agonist Ang-1 to the Tie2 receptor p...
Ngày tải lên : 25/10/2012, 10:31
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Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"

Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"

... our study the basic retrospective measure of frequency was used ’How many workdays in total have you been sickness absent within the last 12 months?’ According to the majority of the found ... and potentially prevent early disability pen- sion, we performed analysis for 4174 employees be- tween 18 and 45 years of age at study entry. 2. Methods The study is based upon the...
Ngày tải lên : 26/10/2012, 10:03
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Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients

Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients

... Introduction Cystatin C (Cys-C) is a non-glycosylated cationic protein of 13.3 kDa, belonging to the cystatin superfamily of cysteine protease inhibitors [1, 2]. Cys-C is produced by all nucleated ... summary, the usefulness of Cys-C was compared with Cr in terms of the estimation of the steady-state serum trough concentrations of digoxin in Japanese patients. The...
Ngày tải lên : 31/10/2012, 17:08
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Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx

Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx

... phosphorylation activity of the CK2 a subunit [39]. The functional homology of the Stellate protein with the CK2 b subunit rises the f ormal possibility t hat the Stellate protein may take part in the ... other b subunits shown in ou r yeast two- hybrid system experiments, it is reasonable to suppose a possibility of a replacement of one b subunit by another i n the...
Ngày tải lên : 21/02/2014, 15:20
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Tài liệu Báo cáo Y học: Studies into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases pot

Tài liệu Báo cáo Y học: Studies into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases pot

... we also noted the level of activity found in many of the chimeric enzymes. Many of the changes we made resulted in chimeric enzymes with substantially lower activity than the wild-type parents. ... activity to hydroxy- lase activity. The reciprocal experiment allowed the conver- sion of a hydroxylase to a desaturase [26]. The objective of our work was to examine...
Ngày tải lên : 21/02/2014, 15:20
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