... London) for providing the Lanp clone,which was produced from a cDNA originally providedby Dr A. Matilla (ICH, London), Filippo Prischi for help with the gromacs software, and Dr L Masino for helpful ... regions. Among these, h1and h6 are regular a-helices whereas h2,h3,h4and h5sharefeatures of 310-helices. A search for tertiary structuresimilarity performed by dali [22] indicates ... fide fullrepeat.Residues 147–149, which are truncated in the crystalstructure, form a b-hairpin (b7) with the strand 143–145 (b6). This region shares a remarkable similaritywith U2A¢,...