Báo cáo khoa học: " Nitric oxide inhibition rapidly increases blood pressure with no change in outcome in cardiogenic shock: the TRIUMPH trial" pptx

... medicine is all about. Furthermore, the tilarginine- induced increase in systolic blood pressure leads to questions about the use of systolic blood pressure as a surrogate endpoint to predict outcome ... outcome in CS. Overall, treatments targeting the inflammatory cascade, especially the inhibition of the NO pathway, remain as deceiving in MI as in sepsis. T...

Ngày tải lên: 13/08/2014, 03:21

... min 8 min 11 min 14 min 17 min 23 min 32 min 41 min 50 min 59 min 74 min 90 min 110 min 140 min 180 min A B Fig. 1. Spectral changes during the reaction of nitrite with carp hemoglobin at different ... min 11 min 14 min 17 min 23 min 32 min 41 min 50 min 59 min 68 min 77 min deoxyHb mixture of HbNO and metHb 450 500 550 600 650 700 0.0 0.5 1.0 1.5 2.0 2.5 Wavelength (nm) 0 min 2 min 5 min...

Ngày tải lên: 16/03/2014, 06:20

... NONOate family [39] inversely correlates with the magnitude of the observed inhibition of the phosphory- lation of EGFR in intact cells. NONOates, in contrast with other NO • donors such as SNAP ... signal-regulated protein kinases 1 and 2; JNK1/2, c-Jun N-terminal kinases 1 and 2; MAPK, mitogen-activated protein kinase; MEK, MAP/ERK kinase; NOIPP-58, nitric oxide- induce...

Ngày tải lên: 17/03/2014, 03:20

... whether Utp25p binds directly to the snoRNA U3 or associates via interaction with the proteins Sas10p and Mpp10p remains to be addressed. The fact that no known RNA-binding motifs can be distinguished ... C-terminal portion, divergences in the remaining sequence of the protein would render hUtp25p nonfunctional and ⁄ or unstable in yeast. To analyze the possibility that t...

Ngày tải lên: 22/03/2014, 21:21

... material Competing interests The authors declare that they have no competing interests in this study. Authors' contributions GZ and AS participated in the design of the study and performed the statistical analysis ... radiochemotherapy with vinorelbine plus cisplatin or carboplatin in patients with locally advanced non-small-cell lung cancer (NSCLC) and an increase...

Ngày tải lên: 09/08/2014, 08:23

... address this issue. In our large single-institution study, we report the clinical outcome and pattern of failure of 3D-CRT without ENI in treating NSCLC after staging with PET scanning. Methods Patient ... treated at our institution with definitive radiation therapy with or without concurrent chemotherapy (CHT). All patients were treated with 3D-CRT, including nodal regions de...

Ngày tải lên: 09/08/2014, 09:22

... central venous blood samples were obtained, along with measurement of cardiac indices using the thermodilution technique. The group found excellent correlation between Cv–a CO 2 and Mv–aCO 2 , with ... regarding the indications, timing and technique for tracheostomy seems to have been raging ever since the procedure itself was first described in ancient Egypt [1]. The topic...

Ngày tải lên: 12/08/2014, 22:22

... purpose-built routine written in MatLab (Mathworks). The lung contours, including the mediastinum, were traced manually to define the region of interest. The presence of hyperinflation (-1,000 ... areas at the expense of hyperinflating otherwise normally aerated areas, in non-dependent lung regions, suggesting that the hidden effect of PEEP is the overdistension of some alve...

Ngày tải lên: 13/08/2014, 03:20

... synthase. The increased activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased and effective recycling of citrulline to arginine in anoxia, making nitric oxide ... provide increased substrate for arginase (50). No significant changes in the activity of arginase in the anoxic group indicate that there is no enhanced utili- zation...

Ngày tải lên: 26/10/2012, 09:07

... generated with the help of the MFOLD program [33] shows that the 5¢-GUC 665 -3¢ target sequence is not involved in hydrogen bonding. However, the availability of the 5¢-CUC 825 -3¢ triplet, which is the ... factors including their intracellular concentration, an effective export from the nucleus to the cytoplasm, a colocalization of the ribozyme with the target RNA a...

Ngày tải lên: 08/03/2014, 08:20