Báo cáo khoa học: "Prediction of death and prolonged mechanical ventilation in acute lung injury" ppt

... utilization and in establishing protocols for clinical studies of acute lung injury (ALI). We aimed to identify risk factors for a combinedend-point of death and/ or prolonged ventilator dependence and developed ... oxy-genation index were lacking (mean airway pressure and FiO2/PaO2) may have been improving clinically and undergoingweaning attempts.Although our choice of a combined outcome including death and ... distribution, and reproduction in any medium, provided the original work is properly cited.AbstractIntroduction Prediction of death and prolonged mechanical ventilation is important in terms of projecting...

Báo cáo khoa học: "Bench-to-bedside review: Chest wall elastance in acute lung injury/acute respiratory distress syndrome patients" docx

... importance of chest wall elastance in characterizing acute lung injury /acute respiratory distresssyndrome patients and in setting mechanical ventilation is increasingly recognized. Nearly 30% of patients ... of its components and theirinteractions [1]. The common increase in the elastance(decrease in compliance) of the whole respiratory system in acute lung injury (ALI) and in acute respiratory ... causes of pleural pressure increases and the clinical consequences of elevated pleural pressure.Measuring pleural pressure and intra-abdominal pressureThe only method available in clinical...

Báo cáo khoa học: "Computer simulation allows goal-oriented mechanical ventilation in acute respiratory distress syndrome" ppt

... ventilator setting providingnormocapnia at a PPLAT of 30 cmH2O at 40 breaths/min. In spite of the high starting frequency, further gains in terms of amodest but significant reduction in VT could ... breaths/min,which is much higher than usually applied in conventional mechanical ventilation. At RRHIGH and at ASPIDS, PEEPTOTwas 18 and 17 cmH2O. This was efficient in maintaining lung aeration, ... with xylazine (2mg/kg) and anaesthetized with ketamine (15 mg/kg). Duringthe experiment anaesthesia was maintained by the continuousintravenous infusion of fentanyl (60 μg/kg·per hour) and mida-zolam...

Báo cáo khoa học: "Causes of death and determinants of outcome in critically ill patient" pot

... per minute, AVP, epinephrine, norepinephrine, combination of catecholamines, IABP, VADGastrointestinal Normal gastrointestinal function, no bleedingIleus >7 days or bleeding requiring ... <250Renal Creatinine ≤ 2.0 mg/dl Creatinine >2.0 mg/dl; doubling of creatinine in patients with previous compensated renal failureContinuous veno-venous haemofiltrationHepatic Bilirubin <2 ... evaluated.Study endpoints were to evaluate causes of death and riskfactors for death in the ICU, in the hospital after discharge fromICU, and within one year after ICU admission. Causes of death in the ICU...

Báo cáo khoa học: Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans docx

... kDa), c-globulin (158 kDa), ovalbumin(44 kDa), myoglobin (17 kDa) and vitaminB12 (1.35 kDa) standards. (Lower) Fractionscontaining standards and analyzed proteins of (1) GST–mSPS1 and (2) His–mDLP1, ... of pSTVK28. pSTVhDLP1 was digested withBamHI and HindIII and cloned into the same sites of pQE31 to yield pQhDLP1, which was in turn digested withXhoI and HindIII and cloned into the SalI and ... heterologous combinations, namely, mSPS1 and hDLP1 or hDPS1 and mDLP1, generated both Q9 and Q10, indicating both components areinvolved in determining the ubiquinone side chain. Thus, we identiﬁed...

Báo cáo khoa học: "Outcomes of resection and non-resection strategies in management of patients with advanced colorectal cancer" doc

... of stentingwas introduced and developed in the unit during thestudy period and in the future may reduce the need foremergency surgical intervention and stoma formation in patients presenting ... systematicreview examined the role of SEMS in this situation and showed successful palliation in 90% of 336 reported caseswith technical failure reported in 8% of cases and perfora-tion in 4% [12]. In this ... optimise QoL and survival taking into account the side effects and risks of any active intervention. In patients that present requiringemergency surgery, due to perforation or bleeding, thedecision...

Báo cáo khoa học: "Density of CD4(+) and CD8(+) T lymphocytes in biopsy samples can be a predictor of pathological response to chemoradiotherapy (CRT) for rectal cancer" ppt

... response and the characteris-tics of tumor-infiltrating lymphocytes (TIL) in rectaltumors. In this study, we used immunohistochemicalstaining and examined the distribution and cell den-sity of ... RC, we retrospectively examined the density of tumor infiltrating CD4(+) and CD8(+) T cells using immunohistochemical staining of biopsy samples before CRT, and examined the correlationwith tumor ... find-ing is in line with the data in this study, and suggestedthat the maintenance of circulating lymphocytes numbercan recruit many anti-tumor lymphocytes into the irra-diated tumor during...

báo cáo khoa học: "Dysregulation of CXCL9 and reduced tumor growth in Egr-1 deficient mice" doc

... hypothesized that it wasbeing made in situ by some type of invading host-derivedWeight of tumors grown in wild type and knockout miceFigure 1Weight of tumors grown in wild type and knockout mice. ... tumors after 12 days of growth in knockout mice and performed immunofluorescencestaining using antibodies against Mig. We found punctatestaining that colocalized with expression of CD68, whichis ... tumors in vari-ous models. In a mouse model of Burkitt's lymphoma,intra-tumoral injection of Mig protein results in partialnecrosis of the tumor [5]. Likewise, adenoviral delivery of the...

báo cáo khoa học: "Inhibition of angiogenesis- and inflammation-inducing factors in human colon cancer cells in vitro and in ovo by free and nanoparticle-encapsulated redox dye, DCPIP" pptx

... the design planning of allexperiments. PP participated in the design of XTT, CAM and Western experi-ments, assisted in data analysis and interpretation and in writing and revisingthe manuscript. ... assay and GEM assay experiments, assisted in data analysis and inter-pretation and in writing and revising the manuscript. SP and JG carried out theWestern blot experiments. CH and SA assisted in ... anti-angiogenesis and anti-inflammation agents in a human colon cancer HCT116 cell line in vitro, and in induced angiogenesis in ovo.Results: The studies described in this report indicate that (a) DCPIP inhibits...

báo cáo khoa học: " Identification of miRNAs and their target genes in developing soybean seeds by deep sequencing" doc

... of the Insti-tute of Genetics and Developmental Biology, ChineseAcademy of Sciences, in Beijing in May. Seeds from soy-beans 15 days after flowering (DAF) were collected and quicklyfrozeninliquidnitrogen.TotalRNAwasisolated ... (Invitrogen) and 0.25 U/μl RNase Inhibitor (Invitro-gen). The 10 μl reactions were incubated in a BiometraTProfessional Thermocycler in a 96-well plate for 30min at 16°C, 30 min at 42°C and ... correspondingtarget genes and study of their roles will elucidate possi-ble functions of miRNAs and target genes in relevantprocesses of seed development.Figure 8 GO analysis of targets of known and...

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