... Cd4(Scys)11cluster in the a domain being adamantane-like in structure.Thus, the Cd4 a domain observed from many mamma-lian species is characterized by a derivative-shaped CDsignal and a distinct NMR ... of the a domain of nativehuman metallothionein 1a but also includes aminoacids not found in the native protein. The four diva-lent metal ions are labeled as 1, 5, 6 and 7 in accor-dance with ... Irvine, CA, USA), zincsulfate (Caledon Laboratory Chemicals, Georgetown,Canada), ammonium formate buffer (Sigma-Aldrich,Oakville, Canada), ammonium hydroxide (BDH Chemi-cals ⁄ VWR, Mississauga,...