Báo cáo khoa học: "Drotrecogin alfa (activated) in patients with severe sepsis and a high risk of death" ppsx

Ngày tải lên: 13/08/2014, 03:20

... cited. Abstract Introduction We report data from adult and pediatric patients with severe sepsis from studies evaluating drotrecogin alfa (activated) (DrotAA) and presenting with purpura fulminans (PF), ... thromboplastin time; BL, baseline; DrotAA, drotrecogin alfa (activated); ICH, intracranial hemorrhage; PT, prothrombin time; UD, unknown day after infusion. A d...

Ngày tải lên: 12/08/2014, 22:21

... ranks. ADDRESS, ADministration of DRotrecogin alfa (activated) in Early Stage Severe Sepsis; APACHE, Acute Physiology and Chronic Health Evaluation; SD, standard deviation. Table 4 Summary of ... Adminis- tration of Drotrecogin alfa (activated) in Early Stage Severe Sepsis (ADDRESS) Study Group: Drotrecogin alfa (activated) for adults with severe se...

Ngày tải lên: 13/08/2014, 11:22

... 1 patient) received an adjuvant chemoradiation. All patients had an abdominal radical hysterectomy and a pelvic lymphadenectomy. Prior to therapy, a chest X-ray and abdominal ultrasound was performed ... considerable rate of gastrointesti- nal and genitourinary morbidity in patients with cervical cancer undergoing pelvic irradiation [10]. With a plati- num based chemor...

Ngày tải lên: 09/08/2014, 09:20

... observation of increased bacterial translocation in patients with IAH and abdominal compartment syndrome [17] may also apply to patients with SAP. Animal studies have shown an increased rate of bacterial ... The analysis included 44 patients, and IAP measurements were obtained from 27 patients. IAH was found in 21 patients (78%). The maximum IAP in these patients a...

Ngày tải lên: 12/08/2014, 22:22

... drafting, revision, and approval of the manuscript. MM (Mealer) was involved in the collection, analysis, and interpretation of the data; provision of study materials and patients; and approval of the manuscript. ... and drafting, revision, and approval of the manuscript. SE was involved in the collection, analysis, and interpretation of the data; provision of...

Ngày tải lên: 12/08/2014, 20:21

... that remains between the Adminis- tration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) trial [3] and the Recombinant Human Activated Protein C Worldwide Evaluation of ... commentary [2] analyzing current evidence for drotrecogin alfa (activated) (DrotAA) in the treatment of severe sepsis. Agarwal and Nath argue that our meta-analysis...

Ngày tải lên: 13/08/2014, 03:20

... Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) study [1], Abraham and colleagues assessed the role of DrotAA in patients with severe sepsis and low risk ... complete a number of phase IV studies evaluating the use of DrotAA in lower -risk patients with severe sepsis, in children with severe sepsi...

Ngày tải lên: 13/08/2014, 03:20

... 344:699-709. 3. Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL, Francois B, Guy JS, Bruckmann M, Rea-Neto A, et al., for the Administration of Drotrecogin alfa (activated) in Early Stage Severe ... 1 Meta-analysis of PROWESS and ADDRESS patients with APACHE II score (AP) ≥ 25 using output from standard meta-analysis software (Review Manager, Version 4.2). T...

Ngày tải lên: 13/08/2014, 03:20

... some of which are (a) nasals in Tamil (Shanmugam, 1972) and Malayalam (Shanmugam, 1972; Ladefoged and Maddieson, 1996), (b) laterals in Albanian (Lade- foged and Maddieson, 1996), and (c) stops in ... con- centrated at around 0. This indicates that though 3 Binning is the process of dividing the entire range of a variable into smaller intervals and counting the number...

Ngày tải lên: 22/02/2014, 02:20