Báo cáo khoa học: "The diagnosis of adrenal insufficiency in the critically ill patient: does it really matter" pps

... Because these criteria are based on limited data, it is likely that these diagnostic thresholds will be refined with time. However, it is important to stress that the diagnosis of adrenal insufficiency in ... adrenal insufficiency in critically ill patients should not be made on the basis of laboratory criteria alone. Competing interests The author declares tha...

Ngày tải lên: 13/08/2014, 03:20

... examined microscopically with or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at ... a role in the regulation of adipose functions associated with obesity. Results miR-27 inhibits adipogenic differentiation In order to investigate the role of miRNAs...

Ngày tải lên: 18/02/2014, 08:20

... quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254. 40 Laemmli UK (1970) Cleavage of structural proteins during the assembly of ... assistance interactions to the developing charge of the r-complex o-nitro group [33]. The comparison of the crystal structure of the rat M1- 1 GST in complex wit...

Ngày tải lên: 15/03/2014, 09:20

... FEBS the involvement of multiple domains of FPR in recogni- tion of the agonist fMLF, including the first, second, and third extracellular loops. The TMs in FPR are also implicated in contributing ... amino acids in the first extracellular loop and the flanking second and third TM (Fig. 1). It is hypothesized that these nonconserved residues may determine the specifi...

Ngày tải lên: 16/03/2014, 18:20

... running in opposite direc- tions. The monomer association involves the ATP-using C-terminal domains interacting near the base of that side of the wedge outside; the N-terminal domains form the ... domain and then rebinding to a second mobile lipoyl domain faster than releasing from the singly held state [21]. Each of the lipoyl domains of E2 is concentrated within t...

Ngày tải lên: 17/03/2014, 09:20

... decrease in the catalytic activity when the allosteric site is occupied by the inhibitor, in comparison with the parental enzyme NADP-ME3 (Table 1). In the case of ME3.2 ¢, the inhi- bition by ... the percentage of activity in the presence of the effectors in relation to the activity measured in the absence of the metabolites, for each of the re...

Ngày tải lên: 23/03/2014, 04:20

... straight line, indicating that p-amindinobenzamidine is a c ompetitive inhibitor for the t rypsinogen autoactivation reaction. From the slope and intercept of the straight line, the kinetic parameters ... shows the effect of increasing inhibitor concentration on the kinetic parameters of trypsinogen autoactivation. The dominant effect of the inhibitor concentration app...

Ngày tải lên: 23/03/2014, 13:20

... of point mutations in the binding domain of a-2-C on the binding to c¢-2 To elucidate whether single amino acids in the binding domain of a-2-C were particularly important for the formation of ... a-subunit contains the carb- oxyltransferase domain in its N-terminal portion and the biotin-binding domain in its C-terminal portion. The c-subunit plays a profound ro...

Ngày tải lên: 23/03/2014, 13:20

... localization of endocrine cells in the principal pancreas of Silurus asotus and Siniperca scherzeri have not yet been reported. In addition, the localization of these endocrine cells within the pancreatic islets ... that the principal pancreatic islets of the two species of teleostean fishes, having similar feeding habits, contained insulin-, glucagon, somatostatin- an...

Ngày tải lên: 07/08/2014, 14:23

... summarizes the expression of Bcl-2 by cell phenotype. The intensity of Bcl-2 staining in neurons in EAE was weaker than in neurons in the normal and CFA- immunized groups. It suggests that the decreased ... normal rat spinal cord (Fig. 2A). In EAE lesions, Bcl-2 immunoreactivity was found in some inflammatory cells in the perivascular cuffing, rather than in th...

Ngày tải lên: 07/08/2014, 15:20