Báo cáo khoa học: "Live and let die: asymmetric dimethylarginine and septic shock" potx

... Cardiovascular biology of the asymmetric dimethylarginine: dimethylarginine dimethylaminohydrolase pathway. Arterioscler Thromb Vasc Biol 2004, 24:1023-1030. 11. Böger RH: Asymmetric dimethylarginine (ADMA): ... generation and the pathophysiology of sepsis. Potential interrelation of nitric oxide (NO) generation by inducible nitric oxide synthase (iNOS) and by asymmetric dimet...

Ngày tải lên: 13/08/2014, 03:20

... levels of NT-proBNP reported during septic shock. Secondly, cardiac dysfunction during sepsis is complex and can be associated with left and right as well as systolic and diastolic dysfunctions [10,11]; ... value for the presence of cardiogenic shock [2]. In septic shock patients, several studies have reported very high levels of BNP and NT-proBNP [4-7] and have suggested that N...

Ngày tải lên: 13/08/2014, 03:20

... were pooled and dialyzed against a sodium acetate buffer (200 mm, pH 4.0). XBS and XAN All purified XBS, XAN and mutant variants were free from protein impurities as verified by SDS ⁄ PAGE and silver ... affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases Sven Cuyvers, Emmie Dornez, Mohammad N. Rezaei, Annick Pollet, Jan A. Delcour and Ch...

Ngày tải lên: 14/02/2014, 19:20

... [19], and 50- and 20-fold decreased inhibi- tion by indinavir and SQV [17,18]. Unlike Ile50, Ile54 does not directly interact with APV, but mutations of Ile54 are frequent in APV resistance and ... mechanisms of resistance and help in the design of new inhibitors. Results APV inhibition of PR and mutants The kinetic parameters and inhibition constants of APV for PR WT and the...

Ngày tải lên: 18/02/2014, 04:20

... a-defensin-1 and a-defensin-2 stimulate the proliferation of lung fibroblasts. a-defensin-1 and a-defensin-2 also increased collagen-I mRNA (COL1A1) levels and protein contents of colla- gen-I and active ... total b-catenin and collagen-I and cell proliferation in lung fibroblasts. Lung fibroblasts HFL1 were incubated with or without a-defensin-1 and a-defensin-2 (2.5 l M) in the p...

Ngày tải lên: 18/02/2014, 06:20

... intra- cellular and extracellular compartments: HepG2 cells were incubated for 6 h under normoxic and hypoxic conditions in the absence and presence of pyruvate (1 m M). Intracellular and extracellular ... electrophoresis, which allows detection of single-strand and double-strand breaks. Cells cultivated in Petri dishes (25 mm in diameter) were suspended in 0.5 mL of NaCl ⁄ P i , a...

Ngày tải lên: 18/02/2014, 16:20

... association rate constants are similar between NP and MP and between HP and HPO in accordance with the similar shapes and sizes between NP and MP and between HP and HPO. The different K d values are proportional ... both DHNP and DHMP. The initial DHNP and DHMP concentrations for these data were 29.7 and 0.3, 19.8 and 0.2, 9.9 and 0.1 l M, respectively. Data 4, 5, 6, 9...

Ngày tải lên: 19/02/2014, 00:20

... analysis of ligand binding to C-LytA. (A) Con- formational changes induced by ligands on C-LytA monitored by near-UV CD with no ligand added (—) and upon addition of ligands: s, d, 2.5 and 20 m M ... min. Experimental con- ditions depended on the enzyme, and were set as follows: 37 °C and pH 6.9 for LytA; 30 °C and pH 6.0 for LytC; and 30 °C and pH 6.9 for Pce. The specific activ...

Ngày tải lên: 19/02/2014, 05:20

... Rad51 is thought to bind single-stranded tails produced at DSB sites, and to form a helical nucleoprotein filament. The single-stranded DNA (ssDNA) and double-stranded Keywords DNA binding; DNA repair; ... 6, 10, 14, 18, 22, 26, and 30), 2 l M (lanes 3, 7, 11, 15, 19, 23, 27, and 31), and 4 lM (lanes 4, 8, 12, 16, 20, 24, 28, and 32). Y. Matsuo et al. Roles of the HsRad51 L1 and...

Ngày tải lên: 19/02/2014, 06:20

... the cytokinin content of 7- and 14-day-old plants. pH optimum and substrate specificity of barley CKX The effect of pH on the activity of recombinant HvCKX2 and CKXs from grain, root and leaf extracts of ... both mature grains and developed seedlings. Transcripts of four TaCKX ge nes (TaCKX2, TaCKX4, TaCKX5 and TaCKX6) were observed in an mRNA pool collected after the infection of...

Ngày tải lên: 19/02/2014, 16:20