Báo cáo khoa học: "Effects of descending positive end-expiratory pressure on lung mechanics and aeration in healthy anaesthetized piglets" docx
... and overdistension of healthy lungs under general anaesthesia. The correspondences and contrasts between E rs and the distributions of lung aeration, and partic- ularly the distribution of lung ... significant). Figure 2 Median lung aeration distribution during positive end-expiratory pressure (PEEP) titrationMedian lung aeration distribution during positiv...
Ngày tải lên: 13/08/2014, 03:20
... cuts One lobe of the thyroid gland of each rat was obtained and fixed in 4% paraformaldehyde overnight and stained using hematoxylin-eosin (H&E). Histological cuts were examined under standard ... III (Positive control). Conclusion: Both a significant increase of TSH and decrease of T4 can be induced as early as day 40 after a low dose of I 131 in rats. Restore of n...
Ngày tải lên: 11/08/2014, 08:20
... separated bands, TLC plates were dipped into a charring solution consisting of 0.63 g of MnCl 2 Æ4H 2 O, 60 mL of water, 60 mL of methanol and 4 mL of concen- trated sulfuric acid, briefly dried and ... arginine at the extreme N-terminus, is targeted for degradation by the enzymes of the N-end rule. A pro- tein–protein interaction therefore results in nongrowth on medium la...
Ngày tải lên: 18/02/2014, 13:20
Báo cáo khoa học: Effect of 5-lipoxygenase inhibitor MK591 on early molecular and signaling events induced by staphylococcal enterotoxin B in human peripheral blood mononuclear cells doc
... inhibitors on SEB-induced TNF-a induction The investigation then focused on analyzing the effect of the same set of inhibitors on TNF-a induc- tion (Table 1). The observed induction in SEB trea- ted ... mass of 40–44 kDa and are activated by the phosphorylation of both threonine and tyrosine residues conserved in the threonine-glutamate-tyrosine motif [10]. P38kinases ar...
Ngày tải lên: 30/03/2014, 04:20
báo cáo khoa học: " Overview of the VA Quality Enhancement Research Initiative (QUERI) and QUERI theme articles: QUERI Series" docx
... stakeholders within and outside the VA. With those aims in mind, QUERI Centers are responsible for monitoring, understanding, evaluating, and acting upon both emerging clinical research findings and implementa- tion ... findings into clini- cal actions. For instance, since 1946, VA has conducted multi-site clinical trials and has maintained a network of regional support centers th...
Ngày tải lên: 11/08/2014, 16:21
Báo cáo y học: "Effects of simulated altitude (normobaric hypoxia) on cardiorespiratory parameters and circulating endothelial precursors in healthy subjects" potx
... main limitations of all studies based on circulating EPCs enumeration consist in the lack of a uniform immunophenotype definition of EPCs and therefore of an experimental method to discrim- inate ... high-altitude hypoxia and exercise is able to switch on the endothelial colony-forming unit capacity [22]. Conclusion In conclusion, the cellular and molecular data indicate...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo khoa học: " Use of intranasal mupirocin to prevent methicillin-resistant Staphylococcus aureus infection in intensive care units" docx
... with signs of infection in accordance with the definitions of the Centers for Disease Control and Prevention. c Defined as imported if they tested positive within 48 hours of admission, and as ... Monte A, Massarutti D, Proietti A, Grazia Troncon M, Lesa L, Zussino M: Reduction in gram-posi- tive pneumonia and antibiotic consumption following the use of a SDD protocol in...
Ngày tải lên: 12/08/2014, 22:21
Tài liệu Báo cáo khoa học: Effects of sequestration on signal transduction cascades docx
... response of the active fraction to a change of the kinase concentration as a function of the concentra- tions of the two forms ([T] and [T*]) and the elastici- ties of the enzymes by the following ... Solid line: the case of kinase sequestration, dotted line: no kinase sequestration. Grey lines indicate the stimu- lus (i.e. kinase concentration), scaled by 0.1 in (A). Effect...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production pot
... effectiveness of compound 4 on PRMT1 inhibition was dependent upon the substrate used, with methylation of GST–GAR being more responsive to inhibition than histone 4. A histone 4 and an arginine- rich and ... activity and IL-2 secretion [6]. Addi- tionally, arginine methylation regulates cytokine gene transcription in T helper (Th) cells through arginine methylation of the NFA...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Epoxidation of benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 in reconstituted membranes Effects of charge and nonbilayer phase propensity of the membrane pot
... of r eductase and NADPH proving the conclusion that the observed effects are indeed related to lipid-ind uced conformational changes of CYP1A2. So far we discussed only the effect of lipids on ... the activation of the CYP1A1-catalyzed epoxidation reaction of 7,8-diols a nd the enhanced nonbilayer phase propensi ty in membranes containing PtdEtn. Effect of lipids on the st...
Ngày tải lên: 08/03/2014, 10:20