Báo cáo khoa học: "Timing of drotrecogin alfa (activated) treatment in severe sepsis" pps
... 1 of 2 (page number not for citation purposes) Available online http://ccforum.com/content/10/4/419 The effect of the timing of drotrecogin alfa (activated) (DrotAA) treatment on the outcome of ... involved pathogen in these pneumonia patients (seven of 12 cases, 58%). Notably, and in contrast to the analysis of the INDEPTH data, hospital mortality rates were compara...
Ngày tải lên: 13/08/2014, 02:24
... purposes) Vol 10 No 3 Research Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis Jean-Louis Vincent 1 , James O'Brien ... leading cause of death in the intensive care unit, and its incidence is increasing [1,2]. Among the many compounds evaluated for the treatment of severe...
Ngày tải lên: 12/08/2014, 23:23
... role of AP-2a and AP-2e in chondrogenesis. Overview of the differen- tiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin-stained section of ... syndrome has over- lapping features, such as orofacial clefting and occa- sional lip pits, with Van der Woude syndrome, in which disruption of an AP-2a-binding site within an interfero...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx
... & Barter P (2006) Effect of inhibiting cholesteryl transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: in vivo studies in rabbits. Arterioscl Thromb ... be sufficient to inhibit lysosomal degradation of modified proteins. Interestingly, apoB from oxidized LDL has been shown to accumulate in secondary lysosomes in macrophages be...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khóa học: Suppression of b1,3galactosyltransferase b3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans Lydia Mare and Marco Trinchera pdf
... purification of the included volume of the column in (A), large O-glycans (j), obtained as the included volume of the column in (C), and small O-glycans (s), obtained as the included volume of the ... with a linearized plasmid containing a 553-bp fragment of b3Gal-T5 cDNA, that includes the initial 360 bp of the coding sequence and 192 bp of the 5¢ untranslated region of th...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: "Integration of Large-Scale Linguistic Resources in a Natural Language Understanding System" pdf
... automatically. 3 Default Linguistic Information If information about a word is not found in any of our linguistic resources, the NL Engine can guess the required information. An unknown word ... usable interpretation of an input utterance containing an unknown word. 4 LAN Operation Each linguistic server can be used to respond to multiple developers, or to multiple instances o...
Ngày tải lên: 20/02/2014, 18:20
Tài liệu Báo cáo khoa học: Localization of N-linked carbohydrate chains in glycoprotein ZPA of the bovine egg zona pellucida pptx
... expression of the sperm-binding activity of the neutral N-linked chain of ZPB. In ZPC, the triantennary/tetraantennary chains are mainly localized at Asn271 in the C-terminal region [13]. The sperm-binding ... many sulfates are linked to the N-acetyllactosamine repeats of porcine zona proteins [7,24]. The N-linked chains of the bovine zona Fig. 4. Anion-exchange HPLC of N-link...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: Role of the C-terminal extension in a bacterial tyrosinase Michael Fairhead and Linda Thony-Meyer doc
... tyrosinase 320 amino acids Core domain 36–357 Copper binding motif Arg40 Cys84 Tyr349 Tyr347 Copper binding motif Trypsinisedpro-tyrosinase 332 amino acids Core domain 36–370 Copper binding ... motif Arg40 Cys84 Tyr349 Tyr347 Lys370 Ala36 Ala36 Ala36 Val357 Phe518 B Laccase Tyrosinase β -sheet protein Fig. 1. Overview of the tyrosinase gene and surrounding genes in the genome of...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt
... accumulates in cyto- plasmic foci in 5–20% of cells under stress condi- tions (Fig. 5B), suggesting that the N-terminal domain of Lsm1p is sufficient in combination with the Sm and C-terminal domains of ... accumulation for the latter, indicating that in the absence of an N-terminal domain distinct localization is lacking. Finally, the Lsm1p Sm domain by itself (LsmDN1DCp) accu...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity docx
... enzyme. Binding of oxidized FMN to the mutant proteins To characterize the serine mutant proteins in further detail, binding of the oxidized FMN cofactor to the isolated apoproteins was investigated ... double-mutant protein, in contrast to the single-mutant proteins (Ser16Ala and Ser127Ala) is not capable of forming the flavin-derived intermedi- ate. The decay rate of the intermed...
Ngày tải lên: 07/03/2014, 05:20