Báo cáo khoa học: "The low-dose ACTH test in the ICU: Not ready for prime time" ppsx

Báo cáo khoa học: "The low-dose ACTH test in the ICU: Not ready for prime time" ppsx

Báo cáo khoa học: "The low-dose ACTH test in the ICU: Not ready for prime time" ppsx

... insufficiency in patients with septic shock, including the 250 µg ACTH stimulation test (standard or “high- dose” test) , the 1 µg ACTH stimulation test ( low-dose test) , measurement of random cortisol ... test in the ICU: Not ready for prime time Makito Yaegashi 1 and Arthur J. Boujoukos 2 1 Clinical Fellow, Department of Critical Care Medicine, Unive...

Ngày tải lên: 13/08/2014, 02:24

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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... longer incubation periods. Interestingly, the interruption of TAG synthe- sis preceded the appearance of toxic effects, supporting the notion that it constitutes the initiating event in the process ... divided in two phases according to the intensity and the duration of the stress. An initial adaptive response culminates in the temporary inhibition of protein synthesis...

Ngày tải lên: 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc

Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc

... take into account the variability of the length of the complete domain, the length of the N-terminal fragment was definned as the length of the amino acid sequence preceding the next domain in the ... autonomously. Therefore, we ProDom, N−terminus ProDom, C−terminus Length of the N terminus in % of the deleted domain Length of the C terminus in % of the deleted...

Ngày tải lên: 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx

Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx

... carbinolamine intermediate; III, iminoquinone intermediate; IV, product Schiff base intermediate; V, aminoquinol intermediate. In the oxidative half-reaction the ami- noquinol intermediate is ... XhoI site in the 3¢-end. The amplification product was cloned into the TA cloning vector PCR4-TOPO (Invitrogen, Carlsbad, CA) for sequencing and then subcloned into vector pCDNA II (In...

Ngày tải lên: 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

... of PDZ binding on the interactions of the Grb4-SH2 domain with the ephrinB2(301–333)-pY304 peptide. (A) The PDZ- binding curves are for the fluorescein-labeled peptides including eph- rinB2(301–333) ... determining the binding specificity towards phosphopeptides. For example, the b-sheet structure after the EF3 segment in the Src SH2 does not exist in the Grb4 SH2...

Ngày tải lên: 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc

... Aarhus, Denmark Intrinsic factor (IF) is the gastric protein that promotes the intestinal uptake of vitamin B 12 . Gastric IF from animal sources is used in diagnostic tests and in vitamin pills. However, ... significantly lower for the plant source. In addition, the purification technique for IF from plants was simpler due to expression of the protein in the unsaturated...

Ngày tải lên: 21/02/2014, 00:20

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Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx

Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx

... and mine it very deeply, not necessarily discovering every aspect of the domain but requiring that the various aspects be integrated with one another to produce a coherent whole. Even in the ... its worth by the number of papers published and panels held on the subject. Indeed, it has been so deeply mined that the thought "Oh, no! Not another panel on natural l...

Ngày tải lên: 21/02/2014, 20:20

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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc

Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc

... suggesting that these cyclin-dependent kinase inhibitors are important in the regulation of adipocyte number. The S-phase kinase-associated protein (Skp)1–Cullin- F-box protein (SCF) ubiquitin ligase ... progression in mam- mals is governed at each phase of the cell cycle by various complexes of cell-cycle-related molecules, including cyclins, cyclin-dependent kinases, their inhib-...

Ngày tải lên: 06/03/2014, 01:20

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Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx

Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx

... survival was not markedly compromised by the inhibition of PI3K signaling with LY294002 in a fully supplemented medium and within the tested time period (Fig. 3B, D). QDs induce the formation of LDs in ... stopper into each flask with a syringe, and the flasks were then shaken gently for 24 h at room temperature. The filters were then removed and placed into scintillation vials...

Ngày tải lên: 07/03/2014, 00:20

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Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx

Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx

... induced in the HMG box seems very interesting. Indeed, the bend determined by Raman for the free SRE fos in solution is roughly similar to that formed in SRE fos in the crystal of its complex with the ... and a linear form keeping the same average conformations. Thus, an increase in temperature displaces the equilibrium, increasing the amplitude of motion around t...

Ngày tải lên: 07/03/2014, 09:20

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