Báo cáo y học: "Cerebellum-specific and age-dependent expression of an endogenous retrovirus with intact coding potential" pdf

... upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Cerebellum-specific and age-dependent expression of an endogenous retrovirus with intact coding potential Retrovirology ... This study was conceived and managed by KC. DGG and TI participated in scientific discussions. KHL and MH performed the experiments and KHL g...

Ngày tải lên: 13/08/2014, 01:21

... = 6) and less than 1% (N = 2) of patients, respectively. Seven patients had mixed infections: 1a and 2 in 4 cases, 1a and 1bin 2 cases and 1a and 4 in one case. The viremia levels for HBV and ... determined by ELISA tests and HBV DNA by real-time PCR. HBV serological markers were found in 43% and 44% of patients and controls, respectively. However, the serological and...

Ngày tải lên: 12/08/2014, 01:21

... made substantial contributions to conception and design, and to the analysis and interpretation of the data. TRM and GWC handled acquisition of data. All authors contributed to the manuscript ... Biologic change deferred in light of concerns for new/worsened comorbidity 10 - Clinically stable or improved and patient/physician satisfied, but DAS and DAS change did no...

Ngày tải lên: 25/10/2012, 10:45

... CD4+CD25 bright and (c) CD4+CTLA-4+ cells, and CD4+ lymphocytes synthesizing (b) TGF-β+ or (d) IL-10 was assessed in peripheral blood by flow cytometry before (day 0), and at days 30 and 90 of Rituximab ... the activation and differentiation of B cells, and the production of high affinity auto-antibodies [5,7]. Thus, it is very likely that the hyperactivity of B cells...

Ngày tải lên: 09/08/2014, 08:22

... University of Medicine, Department of Rheumatology and Clinical Immunology (Berlin, Ger- many), Rheumatology Clinic Dr. Gürtler (Neuss, Ger- many) and Laboratory Medicine, Immunology, University Hospitals ... guideline for this autoantibody specific- ity. When anti-CENP-A and anti-CENP-B was combined the specificity significantly increased and the sensitivity remained almost uncha...

Ngày tải lên: 12/08/2014, 14:21

... research Minireview Temporal and spatial patterning of an organ by a single transcription factor Diya Banerjee and Frank J Slack Address: Department of Molecular, Cellular and Developmental Biology, Yale University, ... Biology 2005, 6:205 Figure 1 An outline of the experimental strategy used by Mango and colleagues [8,9] to identify regulatory motifs that specify temporal...

Ngày tải lên: 14/08/2014, 14:21

... article Highly efficient genetic transduction of primary human synoviocytes with concentrated retroviral supernatant Jianmin Yang, Michael S Friedman, Huimin Bian, Leslie J Crofford, Blake Roessler and ... pathways involved in syn- ovial pathophysiology by overexpression of biologically rel- evant transgenes and dominant negative inhibitors in FLS. The limited expansion potential o...

Ngày tải lên: 09/08/2014, 03:24

... identical and 91% similar amino acids to human YKL40, and was only 48% identical to human YKL39. In spite of intense primer design and PCR analysis, it was not possible to obtain any fragments for YKL39 ... mean and standard deviation of each variable were computed. The median and interquartile range were also calculated. A two-way analysis of variance was used to control for...

Ngày tải lên: 09/08/2014, 06:22

... expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus Anthony P Manderson 1,2 , ... cytometry analysis was performed. Three- colour analysis of the splenic and thymic cell populations did not highlight any significant abnormalities (Table 1). Most importan...

Ngày tải lên: 09/08/2014, 07:20

... [27] and in bovine nasal and human articular Figure 3 Profiling gelatinase gene expression and gelatinolytic activity in resorbing cartilageProfiling gelatinase gene expression and gelatinolytic ... readily available, and this explant cul- ture system provides a rapid, reproducible, and reliable model system to study the mechanisms of cartilage degradation and as such has...

Ngày tải lên: 09/08/2014, 08:22