Báo cáo y học: " Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis" doc

... 1 Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis Paul D. W. Kirk 1‡ , Aviva Witkover 2‡ , Alan Courtney 3 , Alexandra M. Lewin 4 , Robin Wait, ... Eiraku N, Tanaka Y, Usuku K, Weber JN, et al: Low frequency of CD94/NKG2A+ T lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis, but not...

Ngày tải lên: 13/08/2014, 01:21

... glycoprotein secreted in plasma. Its precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin (a1m), a low molecular weight plasma glycoprotein, and an inter-alpha-trypsin ... polymeratization of actin by binding actin monomers, etc. As a part of the actin scavenging system, VDBP binds actin released from cells upon injury; wherein these complexes...

Ngày tải lên: 18/06/2014, 19:20

... proteins are known markers, risk factors, or proteins known to be involved in cardiovas- cular disease; e.g. transthyretin, apoA1, fibrinogen, serum amyloid A protein, haptoglobin, plasminogen, and ... laboratory medicin e now plays a crucial role in identifying risk fac- tors, early events, and conditions triggering plaque rup- ture in coronary heart disease [2,3]. The greatest progres...

Ngày tải lên: 20/06/2014, 03:20

... locus previously identified in a multiplex family study [2]. UBASH3B and UBAC2 encode ubiquitin-associated proteins. The ubiquitin system is best described in targeting misfolded or damaged proteins for ... correctly stated that the numbers with each manifestation make such an analysis very pre- liminary, but several other SNPs have been linked to ocular disease specifically, so these f...

Ngày tải lên: 09/08/2014, 14:22

... statistically significant (P < 0.0001 by analysis of variance). Age and gender changes in plasma cytokines in healthy controls To determine whether plasma cytokines levels were affected by age ... circulating cytokine lev- els are different in healthy males and females and are depend- ent on age. Changes in plasma cytokines in scleroderma patients Circulating cytokine le...

Ngày tải lên: 09/08/2014, 14:22

... plants, inbred lines need be genotyped only once, enabling efficient and cost-effective phenotyping of many traits in multiple environments by a broad research community. Population- and family-based ... cross, giving 25 sets of lines, each set having a common parent. A recent study [9,10] examining flowering time in nearly 1 million plants from around 5,000 NAM recombinant inbred lines...

Ngày tải lên: 09/08/2014, 20:21

... risks. In addition, analyzing TBW by BMI method may f urther impro ve to predict a patient’ s hydration level while ECM contains the metabolically inactive parts of the body components including ... significant reduction in body fat in patients with genotype 3. Inter- esti ngly, majo r alter ations in BMI were not present. We suggest a loss in fatty tissue, which might be compen- sa...

Ngày tải lên: 12/08/2014, 04:20

... genes coding for PCNA, PriS, and Gins15. The functional relevance of this cluster encoding proteins conserved in Archaea and Eukarya is strongly supported by statistical analysis. Interestingly, the ... LSIN cluster in all archaeal lineages, we did not find any publication reporting a direct link between S27E, L44E, aIF-2, and Nop10. A genetic study in yeast pointing toward a role of S...

Ngày tải lên: 14/08/2014, 08:21

... fatigue and malaise were found in 12-14% of the cases, asymptomatic hyper-CK-emia in 9%, and definite myopathy in 0.5% of the patients taking telbivudine [2]. In the instruction leaflet the manufacturer ... [4]. In a study on 1370 patients with hepatitis B asymptomatic hyper-CK-emia was more common in patients receiving telbivudine than lamivudin e [5]. Accor ding to the GLOBE-stu...

Ngày tải lên: 12/08/2014, 02:20

... inducing cytokine synthesis in airway epithelial cells [50], mono- cytes [51], and T lymphocytes [52], as increasing the release of SLPI from respiratory epithelial cells [53], and Respiratory Research ... either by being inactivated by increased salt concentration in secretions of CF airways or by being absent from the ASF owing to alteration of the secretory apparatus caused by the dysf...

Ngày tải lên: 12/08/2014, 18:20