Báo cáo y học: " Flexible catalytic site conformations implicated in modulation of HIV-1 protease autoprocessing reactions" pps

... catalysis. Keywords: phenylalanine ammonia-lyase; PAL; MIO; site- directed mutagenesis; homology model. Phenylalanine ammonia-lyase (PAL; EC 4.3.1.5) is a very important plant enzyme that catalyses ... for Organic Chemistry, University of Karlsruhe, Germany; 2 Institute for Organic Chemistry, Budapest University of Technology and Economics, Hungary The plant enzyme phenylalan...

Ngày tải lên: 08/03/2014, 23:20

... class="bi x0 y0 w2 h 1" alt =""

Ngày tải lên: 05/08/2014, 10:20

... disease by destroying target tissues through induction of apoptosis of chondrocytes [33]. Alternatively, Fas could contribute to synovial hyperplasia by inducing proliferation of Fas- expressing synovial ... control mice with CIA reveal less inflammation/joint destruction in DBA-lpr/ lpr mice in spite of the same clinical score as that of control mice. The proinflamm...

Ngày tải lên: 09/08/2014, 01:23

... genotype influences TNFα serum levels in SLE patients without antimalarial treatmentCombined IL-10/tumor necrosis factor (TNF)α genotype influences TNFα serum levels in SLE patients without antimalarial ... Deutsch R, Boyle D: Fcgamma receptor type IIIA polymorphisms influence treat- ment outcomes in patients with inflammatory arthritis treated with tumor necr...

Ngày tải lên: 09/08/2014, 07:20

... http://genomebiology.com/2010/11/2/106 Page 2 of 3 The pea aphid life cycle e ecology, physiology and evolution of the hemipteran insect pea aphid (Acyrthosiphon pisum) has been well studied because of its ... published in this issue of Genome Biology [2]. e genome of the pea aphid is the first to be sequenced of the hemimetabolous group of insects, charac...

Ngày tải lên: 09/08/2014, 20:21

... from a random numbers table created by the principal investigator at a centralized location blinded to all company names. Each participating employer is matched to another participating employer inthesamecoalitionbyworkforcesizebeforethe employer ... intent- to- treat models of all available data to evaluate intervention impact on the purchase of depression products using a...

Ngày tải lên: 11/08/2014, 05:21

... literature search, data collection, data analysis, and manuscript prepara- tion. All authors have read and approve of the submitted manuscript. Author Details Department of Medicine, Howard University ... Kluyvera ascorbata bacteremia. Med Clin (Barc) 1997, 108:479. 5. Oteo J, Gómez-Garcés JL, Alós JI: Acute cholecystitis and bacteremia caused by Kluyvera ascorbata in a cirrhoti...

Ngày tải lên: 11/08/2014, 12:20

... Database Any patient, any case, can teach us something www.casesnetwork.com Case report Open Access Unusual Epstein-Barr esophageal infection in an immunocompetent patient: a case report Magdalini ... esophagitis, a rare condition in an immunocompetent host. In this setting, active infection may represent a primary infection or reactivation. Histopatholog...

Ngày tải lên: 11/08/2014, 17:21

... Brain Res 2002, 952:128. 41. Aguilera A, Selgas R, Ruiz-Caravaca ML, Bajo MA, Cuesta MV, Plaza MA, Hernanz A: Effects of recombinant human erythro- poietin on functional and injury endothelial ... of apoptosis occur for days after a mechanical injury has been sustained [36]. Notably, rhEPO administered even 24 hours after injury is very effective in ameliorating injury (Fig. 1). In...

Ngày tải lên: 12/08/2014, 20:20

... body of evidence in support of the theory that mechanical ventilation may sensitize the innate immune system and that, in turn, the innate immune system may sensitize the lungs to the effects of ... been the subject of a number of reviews [9–14]. The spectrum of VILI includes not only air leaks and increases in endothelial and epithelial permeability, b...

Ngày tải lên: 12/08/2014, 20:21

... coronary artery bypass grafting surgeryLongitudinal evaluation of autonomic cardiovascular tests in patients undergoing coronary artery bypass grafting surgery. Longitudinal auto- nomic cardiovascular ... indexes of heart rate variability before and at various intervals after coronary artery bypass grafting Variable Group Preoperative After surgery 3 days 6 day...

Ngày tải lên: 12/08/2014, 20:21

... A, Y, H, or N completely abolishes enzymatic activity [1-4]. In the HIV-1 infected cell, the protease is initially synthesized as part of the Gag-Pol polyprotein precursor, within which the HIV-1 ... different C-terminal flanking sequences could influence the proteolytic activity of the embedded protease by modulating the catalytic site conformation, revealing an additio...

Ngày tải lên: 13/08/2014, 01:21

... enhancing and inhibitory cellular splicing factors induced by infection suggest that regulation of HIV-1 alternative splicing plays a key role in persistent infection in these important viral ... that in infected lymphocytes. However, changes in expression and possibly localisation of cellular splicing factors known to modulate viral alternat...

Ngày tải lên: 13/08/2014, 06:20

... citation purposes) Vol 13 No 3 Research Heliox reduces respiratory system resistance in respiratory syncytial virus induced respiratory failure Martin CJ Kneyber 1,2 , Marc van Heerde 1 , Jos WR Twisk 3 , ... in infants with respiratory failure caused by respiratory syncytial virus infection. J Pediatr 1995, 147:485-490. 21. Jefferson LS, Coss-Bu JA, Englund JA,...

Ngày tải lên: 13/08/2014, 16:20

... properly cited. Quantitative array data description& lt;p>A new classification- based framework is presented that allows quantitative description of microarray data in terms of significance of co-expression ... interactions information Open Access 2006Sangurdekaret al.Volume 7, Issue 4, Article R32 Method A classification based framework for quantitative desc...

Ngày tải lên: 14/08/2014, 16:21