Báo cáo y học: "Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model" pptx
Tài liệu Báo cáo Y học: Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum pdf
... Biochem. 269) 6061 Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum Surza L. G. Rocha1, Bruno Lomonte3, Ana G. C. Neves-Ferreira1, ... physicochemicaland biological properties of DM64, an antimyotoxic protein from opossum serum. DM64 is an acidic protein showing15% glycosylation and with a molecular mass of 63 659 Dawhen analysed ... deglycosylationDM64 was chemically deglycosylated with anhydroustrifluoromethanesulfonic acid (TFMS) using the GlycoFreekit k-500 from Oxford GlycoSystems, USA and submittedto SDS/PAGE. Human...
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Báo cáo khoa học: Different roles of two c-tubulin isotypes in the cytoskeleton of the Antarctic ciliate Euplotes focardii Remodelling of interaction surfaces may enhance microtubule nucleation at low temperature doc
... compilation ê 2008 FEBS Different roles of two c-tubulin isotypes in the cytoskeleton of the Antarctic ciliate Euplotes focardii Remodelling of interaction surfaces may enhance microtubule nucleation ... transition state in cold thermal regimes.How do the unique features of the E. focardii c-tubu-lins enhance microtubule nucleation by the c-TuRCcomplex at low temperature, and what do these changesimply ... in the nucleation of cellular microtubules. In the present study, we report the characterization of c-tubulin from the psychrophilic Antarctic ciliate Eupl-otes focardii. In this organism, c-tubulin...
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Báo cáo Y học: Defective translocation of a signal sequence mutant in a prlA4 suppressor strain of Escherichia coli doc
... obtain a prlA4 derivative of strain CE1224, a Tn10 marker was introduced close to the prlA4 allele in strain NT1004 by P1 transduction using strain CAG12071 as thedonor and selection for tetracycline-resistant ... anti-bodies directed against leader peptidase and analysis bySDS/PAGE and autoradiography.Proteinase K-accessibility experimentsCells of prlA4 mutant strain NT1004, carrying plasmidpNN8, were grown ... peptidase already appeared to beaccessible to proteinase K in spheroplasts of both the wild-type and the prlA4 mutant strain (Fig. 4A) . The intactness of the spheroplasts was confirmed by the inaccessibility...
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Báo cáo Y học: Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme pptx
... very weak binding.5194 L. Holland et al. (Eur. J. Biochem. 26 9) Ó FEBS 20 02 Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme Linda ... N-Terminally flag-tagged full-length MCM2(1–8 92) (lanes 1 and 5), MCM2(1 23 0)V203E/F204L (lanes 2 and 6), MCM2(1 23 0)L192P/R193G (lanes 3 and 7), and MCM2(1 23 0)wt (lanes 4 and 8) were expressed in 29 3 ... acids169 21 2 to the interaction between MCM2 and RNA pol II holoenzyme. DISCUSSIONMCM2 interacts with pol II holoenzyme We have previously shown that several MCM proteinscopurified with pol II holoenzyme...
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Báo cáo y học: "γ Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity" potx
... demonstrated in the analysis of the role of IFN-γ in models of autoimmunity. Early attemptsto define the role of IFN-γ in autoimmunity by the adminis-tration of IFN-γ or neutralizing antibodies ... simplistic, especially as it pertains to the role of IFN-γ. Keywords: arthritis, autoimmunity, cytokines, IFN-γ Commentary Paradoxical roles of IFN-γγ in models of Th1-mediated autoimmunityEdward F Rosloniec1,2,3, ... role of IFN-γ in CIA by theadministration of IFN-γ or neutralizing antibodies specificfor IFN-γ yielded conflicting results [15–19], probablybecause of variations in timing, sites and means of...
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Báo cáo y học: "Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts" doc
... by Th2 cells were affected strongly by both U-0126 and PSI and weakly by the JNK inhibitor (Fig-ure 6a,c). Finally, IP-10 mRNA levels induced by Th1 cells were decreased by U-0126 and PSI, and ... preferen-tially by Th1 cells and IL-8 mainly by Th2 cells, whereas MCP-1 is induced equally by both subsets. This illustrates thecapacity of fibroblasts to activate flexible patterns of chemok-ine production ... effects of the same quality and magni-tude as those induced by polarized T cells. For instance, IL-8was not induced by any of the Th1 and Th2 cytokines, but wasstrongly induced by Th2 and to...
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Báo cáo y học: "Possible roles of Epstein-Barr virus in Castleman disease" potx
... localization by hematoxylin-eosinstain, immunohistochemistry, polymerase chain reaction and In- situ hybridizationResults: Hyaline-vascular type was diagnosed in 18 cases, plasma cell type in 1 and ... WC: Precision of genotyping of Epstein-Barr virus by polymerase chain reac-tion using three gene loci (EBNA-2, EBNA-3C, and EBER):predominance of type A virus associated with Hodgkin's dis-ease. ... mixed type in 1 case. All of them were positive for Epstein-Barr virus confirmed by PCR. For tumors thatEBER (Epstein-Barr early region) signals mainly localized in the germinal centers have increasedvascularity...
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Báo cáo y học: "Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis" ppsx
... immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysisHooi-Ming Lee1, Hidehiko Sugino1, Chieko Aoki2, Yasunori ... response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis. Arthritis Research &Therapy 2011 13:R89.Submit your next manuscript ... mononuclear cells (PBMC) from RA patients, either by comparingthem with PBMC from healthy individuals or from patients with other autoimmune diseases [1,3]. Of greater interest to us is the accumulating...
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Báo cáo y học: "Defective response of CD4+ T cells to retinoic acid and TGFb in systemic lupus erythematosus" ppt
... defective, eitherbecause there are too many memo ry T cells or they arerefractory to RA inhibition. Interestingly, the CD25-Tregs were also expanded by the combination of RA and TGBb, and these ... regulatory T cells, including that of CD25-Tregsthatwehavefoundtohave lost their regulatory functions (this study). Thisrepresents a novel mechanism of auto-reactive T cellregulation that needs ... factorbeta) TGFb and retinoic acid (RA) in systemic lupus erythematosus (SLE) patients.(a) Treg expansion by RA in the presence of 1 ug/ml of TGFb was negatively correlated with the percentage of...
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Báo cáo y học: "Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non-allergic individuals using 2-dimensional gel electrophoresis and mass spectrometry" potx
... purposes)Respiratory ResearchOpen AccessResearchPsoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non -allergic individuals using 2-dimensional gel electrophoresis and ... 5.3 Proteins in bold are newly identified in NLF.Table 1: Identified proteins in nasal lavage fluid from allergic and non -allergic individuals. (Continued)Western blot analysis of NLF from ... Tagesson C, Lindahl M: Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and pep-tide mass fingerprinting. Proteomics...
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Báo cáo y học: " Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis" pdf
... AccessReview Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesisMasaya Higuchi* and Masahiro FujiiAddress: Division of Virology, Niigata University Graduate ... ubiquitin-editingenzyme A20. The TAX1BP1-A20 deubiquitinase complexis a negative regulator of NF-κB activity induced byinflammatory cytokines; Tax1 can disrupt this inhibitorycomplex to thereby trigger ... that HTLV-1 Tax1 and HTLV-2 Tax2 havemany shared activities, but the two proteins have a limited number of significantly distinct activities,and these distinctions appear to play key roles in HTLV-1...
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Báo cáo y học: "Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model" pptx
... associated with an accumu-lation of these same cells in infected lymphatic tissues,suggesting that Tregs either redistribute to infected tissues,proliferate there, or both [36,55]. Tregs at the ... ‘helper’ T( Th)cells,sinceCD4+ T- cell help is required for both the induction of neutralizingantibodies by mature B cells and for the maintenance of effective cytotoxic T cell (CTL) responses. In the ... CD8+CTLs [39,60-62] thus, prolonging the recovery from acuteFV infection, and allowing the establishment of a chronicinfection. The interplay of different subsets of CD4+ T cells in FV infection...
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Báo cáo y học: "Therapies, School of Biological and Biomedical Sciences, Griffith University, Brisbane 4111, Australia. †The Institute for Molecular Biosciences" pptx
... *Eskitis Institute for Cell and Molecular Therapies, School of Biological and Biomedical Sciences, Griffith University, Brisbane 4111, Australia. †The Institute for Molecular Biosciences, ... thelocation and association of Irak and its targets.Alternate splicing of the Mapk and Pik3 pathways alter inflammatory signaling in macrophagesThe Kyoto Encyclopaedia of Genes and Genomes ... overexpressed isoforms 1 and 3 of Mapk14 in RAW264.7 cells to evaluate the impact of these proteins on inflammatory activation and survival of macrophages (Figure 7). Overexpression of isoform 3 led...
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Báo cáo y học: "Distinct patterns of SSR distribution in the Arabidopsis thaliana and rice genomes" pptx
... 3).Conclusion The SSRs show distinct patterns of distribution among differ-ent regions of the genes in both Arabidopsis and rice genomes. The amounts of differences in the SSRs between the two genomes ... comparison of the SSR densities (for SSRs of period 1 to 10) in the coding (exon) regions of Arabidopsis and rice. Comparison of intron SSR densitiesFigure 3Comparison of intron SSR densities. ... nucle-otides (oftentimes defined as being between 1 and 6 base-pairs (bp)) in DNA sequences. They can be found in anygenome (both eukaryote and prokaryote) and in any region(protein coding regions and...
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Báo cáo y học: "Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions" ppsx
... R80ResearchDevelopmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regionsStewart MacArthurÔ*Ơ, Xiao-Yong ... being with the D-VBroad, overlapping patterns of binding of transcription factors to the genome in blastoderm embryosFigure 3Broad, overlapping patterns of binding of transcription factors to ... map analysis of binding of transcription factors to CRMs In Figure 12a a CRM is defined as being bound by a transcrip-tion factor if it was overlapped by at least 300 bp by one of thefactor's...
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Từ khóa: báo cáo khoa học y họcbáo cáo y họcbáo cáo y học cổ truyềnbáo cáo y tế học đườngmẫu báo cáo y tế học đườngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP