Báo cáo y học: "Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model" pptx

... Biochem. 269) 6061 Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum Surza L. G. Rocha 1 , Bruno Lomonte 3 , Ana G. C. Neves-Ferreira 1 , ... physicochemical and biological properties of DM64, an antimyotoxic protein from opossum serum. DM64 is an acidic protein showing 15% gly...

Ngày tải lên: 21/02/2014, 01:21

... compilation ê 2008 FEBS Different roles of two c-tubulin isotypes in the cytoskeleton of the Antarctic ciliate Euplotes focardii Remodelling of interaction surfaces may enhance microtubule nucleation ... transition state in cold thermal regimes. How do the unique features of the E. focardii c-tubu- lins enhance microtubule nucleati...

Ngày tải lên: 07/03/2014, 04:20

... obtain a prlA4 derivative of strain CE1224, a Tn10 marker was introduced close to the prlA4 allele in strain NT1004 by P1 transduction using strain CAG12071 as the donor and selection for tetracycline-resistant ... anti- bodies directed against leader peptidase and analysis by SDS/PAGE and autoradiography. Proteinase K-accessibility experiments Cells of prlA4 mutant s...

Ngày tải lên: 08/03/2014, 09:20

... very weak binding. 5194 L. Holland et al. (Eur. J. Biochem. 26 9) Ó FEBS 20 02 Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme Linda ... N-Terminally flag-tagged full-length MCM2(1– 8 92) (lanes 1 and 5), MCM2(1 23 0)V203E/F204L (lanes 2 and 6), MCM2(1 23 0)L192P/R193G (lanes 3 and 7...

Ngày tải lên: 17/03/2014, 10:20

... demonstrated in the analysis of the role of IFN-γ in models of autoimmunity. Early attempts to define the role of IFN-γ in autoimmunity by the adminis- tration of IFN-γ or neutralizing antibodies ... simplistic, especially as it pertains to the role of IFN-γ. Keywords: arthritis, autoimmunity, cytokines, IFN-γ Commentary Paradoxical roles of IFN- γγ in m...

Ngày tải lên: 09/08/2014, 06:22

... by Th2 cells were affected strongly by both U-0126 and PSI and weakly by the JNK inhibitor (Fig- ure 6a,c). Finally, IP-10 mRNA levels induced by Th1 cells were decreased by U-0126 and PSI, and ... preferen- tially by Th1 cells and IL-8 mainly by Th2 cells, whereas MCP- 1 is induced equally by both subsets. This illustrates the capacity of fibroblasts to ac...

Ngày tải lên: 09/08/2014, 07:20

... localization by hematoxylin-eosin stain, immunohistochemistry, polymerase chain reaction and In- situ hybridization Results: Hyaline-vascular type was diagnosed in 18 cases, plasma cell type in 1 and ... WC: Precision of genotyping of Epstein-Barr virus by polymerase chain reac- tion using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated wi...

Ngày tải lên: 10/08/2014, 10:20

... immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis Hooi-Ming Lee 1 , Hidehiko Sugino 1 , Chieko Aoki 2 , Yasunori ... response- related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis....

Ngày tải lên: 12/08/2014, 17:21

... defective, either because there are too many memo ry T cells or they are refractory to RA inhibition. Interestingly, the CD25 - Tregs were also expanded by the combination of RA and TGBb, and these ... regulatory T cells, including that of CD25 - Tregsthatwehavefoundto have lost their regulatory functions (this study). This represents a novel mechanism of auto-reactive T...

Ngày tải lên: 12/08/2014, 17:22

... purposes) Respiratory Research Open Access Research Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non -allergic individuals using 2-dimensional gel electrophoresis and ... 5.3 Proteins in bold are newly identified in NLF. Table 1: Identified proteins in nasal lavage fluid from allergic...

Ngày tải lên: 12/08/2014, 18:22

... Access Review Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis Masaya Higuchi* and Masahiro Fujii Address: Division of Virology, Niigata University Graduate ... ubiquitin-editing enzyme A20. The TAX1BP1-A20 deubiquitinase complex is a negative regulator of NF-κB activity induced by inflammatory cytokines; Tax1 can di...

Ngày tải lên: 12/08/2014, 23:22

... associated with an accumu- lation of these same cells in infected lymphatic tissues, suggesting that Tregs either redistribute to infected tissues, proliferate there, or both [36,55]. Tregs at the ... ‘helper’ T( Th)cells,sinceCD4 + T- cell help is required for both the induction of neutralizing antibodies by mature B cells and for the maintenance of effective cytotoxic T...

Ngày tải lên: 13/08/2014, 01:21

... * Eskitis Institute for Cell and Molecular Therapies, School of Biological and Biomedical Sciences, Griffith University, Brisbane 4111, Australia. † The Institute for Molecular Biosciences, ... the location and association of Irak and its targets. Alternate splicing of the Mapk and Pik3 pathways alter inflammatory signaling in macrophages The K...

Ngày tải lên: 14/08/2014, 16:21

... 3). Conclusion The SSRs show distinct patterns of distribution among differ- ent regions of the genes in both Arabidopsis and rice genomes. The amounts of differences in the SSRs between the two genomes ... comparison of the SSR densities (for SSRs of period 1 to 10) in the coding (exon) regions of Arabidopsis and rice. Comparison of intron...

Ngày tải lên: 14/08/2014, 16:21

... R80 Research Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions Stewart MacArthur Ô *Ơ , Xiao-Yong ... being with the D-V Broad, overlapping patterns of binding of transcription factors to the genome in blastoderm embryos...

Ngày tải lên: 14/08/2014, 21:20