Báo cáo y học: "Subunit-specific mutational analysis of residue N348 in HIV-1 reverse transcriptase " docx

... granted by the Ethics Committee of the London School of Hygiene & Tropical Medicine and by the Ministry of Health of the Republic of Trinidad & Tobago. All participants provided informed ... study. Pregnancy outcome: statistical analyses The majority of the analyses described here are pregnancy based. Women were excluded from this analysis if they were aged younger than...

Ngày tải lên: 09/08/2014, 10:22

... also included a YlXRN1 mutant in our analysis. In hybridization studies, we observed a higher intensity of the bands corresponding to intron-retained transcripts in NMD - mutants only. No such increase ... use of alternative promoters. The fre- quency of AS in Y. lipolytica is not very high, particularly if intron retention is excluded from the analysis (1.8% of intron-co...

Ngày tải lên: 09/08/2014, 20:22

... karyotypes by choosing only the first well-defined karyotype it contained. In case of multiple karyotypes from the same patient (’case’ in the Mitelman Database), only one karyotype was taken into ... defined according to tissue morphology and organ. Karyotypes belonging to classes with small representation (< 50 karyotypes) in the remaining dataset were omitted from analysis, res...

Ngày tải lên: 09/08/2014, 23:20

... millimeters in the dromedary and 6 millime- ters in the whale [6]. Gray makes it a point to indicate that the membranous semicircular canal often fills the bony channel, leaving little in the way of perilymphatic ... the legions of individuals may all be a part of a single evolutionary spec- trum. In fact, individual differences in Darwin's view rep- resent the current da...

Ngày tải lên: 13/08/2014, 16:20

... in this study, including ribosomal proteins, proteins involved in energy metabolism, and proteins involved in rRNA processing. These authors also measured a general increase in mRNA stability ... decay in Plasmodium falciparum. We found that, globally, rates of mRNA decay increase dramatically during the asexual intra- erythrocytic developmental cycle. During the ring stage of t...

Ngày tải lên: 14/08/2014, 07:22

... kinase, and protein kinase), containing two, three, and two instances, respectively. In the general motif analysis we identified motifs containing purely noninteracting edge types. It is possible ... cases of genetically nonin- teracting loci. This causes the topology of the network (the simple presence or absence of an edge of any type linking each pair of nodes) to be determin...

Ngày tải lên: 14/08/2014, 08:20

... Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China. ¥ China Agriculture University, 2 West Yuanmingyuan Street, Beijing 10094, China. # College of Life Sciences, Sun Yat-sen ... Unkown WEI10 MDYZ Yush AF48687 MDYZ TCH AF486862 MDYZ QP AF486865 MDYZ X AF486859 URYZ BM2 UMYR QP442 MDYZ QP4014 MDYZ YIMH42 DRYR ERHL AF486861 MDYZ HUZU2 UMYR YMH AF486868 DRYR ABA15...

Ngày tải lên: 14/08/2014, 08:20

... for only 22 amino acids, including the amino acids selenocysteine and pyrroly- sine whose incorporation into protein requires the reassign- ment of the UGA and UAG stop codons, respectively [1,2]. This ... constraint imposed by the mRNA decoding machinery on those ORFeomes, is not yet clear and we are currently inves- tigating this. In any case, this diagonal line in the codon con- text...

Ngày tải lên: 14/08/2014, 14:21

... Currently, it seems that measurement of EVLW using the transpulmonary thermodilution method routinely in clinical practice may have limited value in young children. Lemson and colleagues’ study, ... accurately determined using this scoring system.  e authors are to be commended for completing this study. Overall there are many challenges in the use of this method to measure E...

Ngày tải lên: 13/08/2014, 21:21

... proteins work is unclear. FEM-1 contains ankyrin repeats [8], which often mediate interactions with other pro- teins. In vitro assays show that it binds FEM-2 [9]. FEM-2 is a PP2C-type protein ... coordinated by a secreted protein, HER-1, that binds to and inactivates the receptor protein TRA-2 (reviewed in [7]). Three intracellular proteins, FEM-1, FEM-2, and FEM-3, help transmit this in...

Ngày tải lên: 14/08/2014, 16:21